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DAPI chloride

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Identification
Molecular formula
C16H20ClN5O4
CAS number
28718-90-3
IUPAC name
N,N-diethyl-2-[2-(2-morpholin-4-ium-4-ylethyl)-5-nitro-benzimidazol-1-yl]ethanamine;chloride
State
State

At room temperature, DAPI chloride is in a solid state. It is typically handled in powdered form in laboratory environments.

Melting point (Celsius)
184.00
Melting point (Kelvin)
457.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
350.82g/mol
Molar mass
350.8150g/mol
Density
1.3600g/cm3
Appearence

DAPI chloride appears as a yellow crystalline powder. It is provided typically in a solid form that can be dissolved in water to form a fluorescent stain used to bind to DNA in laboratory settings.

Comment on solubility

Solubility of N,N-Diethyl-2-[2-(2-Morpholin-4-ium-4-ylethyl)-5-nitro-benzimidazol-1-yl]ethanamine; Chloride

The solubility of N,N-diethyl-2-[2-(2-morpholin-4-ium-4-ylethyl)-5-nitro-benzimidazol-1-yl]ethanamine; chloride is influenced by several factors owing to its complex structure. As a quaternary ammonium compound, it generally exhibits good solubility in polar solvents. Here are some key details to consider:

  • Solvent Compatibility:
    • This compound is expected to be highly soluble in water due to ionic interactions involving the chloride ion.
    • It may also dissolve well in alcohols and other polar organic solvents.
  • Effect of pH:
    • Its solubility can vary with changes in pH, especially in solutions where the ionization state of the morpholine group might affect solvation.
  • Temperature Dependence:
    • Typically, an increase in temperature may enhance solubility in most solvents.

In general, the combination of the hydrophilic amine and morpholino moieties contributes to the overall solubility characteristics of this compound. This is a vivid example where the interplay between structure and solvent environment determines the solubility behavior of the chemical compound.

Interesting facts

Interesting Facts About N,N-Diethyl-2-[2-(2-Morpholin-4-ium-4-ylethyl)-5-nitro-benzimidazol-1-yl]ethanamine; Chloride

N,N-Diethyl-2-[2-(2-morpholin-4-ium-4-ylethyl)-5-nitro-benzimidazol-1-yl]ethanamine; chloride is a fascinating compound, particularly in the field of medicinal chemistry. Here are some intriguing insights:

  • Complex Structure: This compound features a remarkable combination of functional groups, including a benzimidazole, which is known for its potential biological activity and is widely used in pharmaceuticals.
  • Biological Significance: The presence of nitrogen and a morpholine ring suggests potential applications in developing new antimicrobial and anti-cancer agents, showing promise as a lead compound in drug discovery.
  • Ionization: The chloride ion plays a crucial role in the solubility of this compound, influencing its pharmacokinetics and interactions within biological systems.
  • Multifunctionality: With its ability to engage in various types of chemical interactions, this compound exemplifies the importance of multifunctionality in drug design.
  • Research Applications: Scientists are actively studying compounds like this for their potential utility in targeting specific biological pathways, contributing to advancements in precision medicine.

As you explore compounds of this nature, remember the words of renowned chemist Marie Curie: "One never notices what has been done; one can only see what remains to be done." This statement rings true in the ever-evolving landscape of chemical research, highlighting the importance of understanding complex compounds and their potential therapeutic roles.

In summary, N,N-diethyl-2-[2-(2-morpholin-4-ium-4-ylethyl)-5-nitro-benzimidazol-1-yl]ethanamine; chloride is not just a compound but a rich field of study that may lead to significant breakthroughs in health and medicine.

Synonyms
Benzimidazole, 1-(2-diethylaminoethyl)-2-(2-morpholinoethyl)-5-nitro-, hydrochloride
1-(2-Diethylaminoethyl)-2-(2-morpholinoethyl)-5-nitrobenzimidazole hydrochloride
19809-12-2
RefChem:325817