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Mebendazole

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Identification
Molecular formula
C16H16N2O3
CAS number
31431-39-7
IUPAC name
N,N-diethyl-2-[2-(2-morpholinoethyl)benzimidazol-1-yl]ethanamine
State
State

Mebendazole is usually found in a solid state as a powder at room temperature.

Melting point (Celsius)
288.00
Melting point (Kelvin)
561.10
Boiling point (Celsius)
574.20
Boiling point (Kelvin)
847.40
General information
Molecular weight
265.35g/mol
Molar mass
265.3490g/mol
Density
1.2307g/cm3
Appearence

Mebendazole is typically found as a white to light yellow powder. It is practically insoluble in water and slightly soluble in methanol and ethanol.

Comment on solubility

Solubility of N,N-diethyl-2-[2-(2-morpholinoethyl)benzimidazol-1-yl]ethanamine

The solubility of N,N-diethyl-2-[2-(2-morpholinoethyl)benzimidazol-1-yl]ethanamine can be influenced by several factors, including temperature, pH, and the presence of different solvents. This compound, characterized by its complex structure, exhibits unique solubility properties:

  • Solvent Compatibility: It is likely to be more soluble in organic solvents such as alcohols and DMSO due to its hydrophobic characteristics.
  • Water Solubility: Its solubility in water may be limited, primarily due to the presence of the biaromatic component which tends to be hydrophobic.
  • pH Influence: The solubility could be affected by the pH of the solution, as ionization of the amine group may enhance solubility in aqueous environments.

As a general guideline, compounds with large nonpolar regions, like this one, often show lower solubility in polar solvents compared to nonpolar solvents. Therefore, it is essential to understand the environmental conditions when assessing solubility.

In conclusion, while specific solubility data for N,N-diethyl-2-[2-(2-morpholinoethyl)benzimidazol-1-yl]ethanamine is not readily available, a careful examination of the factors mentioned above can provide insights into its potential behavior in various solvents.

Interesting facts

Interesting Facts about N,N-Diethyl-2-[2-(2-Morpholinoethyl)benzimidazol-1-yl]ethanamine

N,N-Diethyl-2-[2-(2-morpholinoethyl)benzimidazol-1-yl]ethanamine, often referred to in the scientific community by its more complex name, is a compound that presents intriguing aspects of chemistry. It belongs to the class of benzimidazoles, which are noteworthy for their versatility and utility in medicinal chemistry. Here are some key points to consider:

  • Pharmacological Significance: Compounds like this are often investigated for their potential antitumor and antimicrobial properties, showing promise in the development of new therapies.
  • Structural Diversity: The structure of this molecule highlights the importance of morpholino groups which are frequently used in drug discovery due to their ability to enhance solubility and bioavailability.
  • Mechanisms of Action: Benzimidazole derivatives have been found to interact with a variety of biological targets, including enzymes and receptors, making them crucial contributors to the understanding of drug-target interactions.
  • Research Potential: The unique combination of ethyl groups and the benzimidazole moiety suggests a wide range of potential applications in both pharmaceutical and agricultural chemistry, hinting at new pathways for innovation.

As chemistry students or scientists delve into the world of organic compounds, they often discover that compounds like N,N-Diethyl-2-[2-(2-morpholinoethyl)benzimidazol-1-yl]ethanamine not only contribute to our understanding of chemical properties but also pave the way for advancements in healthcare and technology. The study of such compounds fosters a deeper appreciation for the complexity of molecular interactions and their implications in various fields.