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Ebastine

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Identification
Molecular formula
C32H39N3O2
CAS number
90729-43-4
IUPAC name
N,N-diethyl-2-[2-(4-methoxyphenyl)benzimidazol-1-yl]ethanamine
State
State

Ebastine is typically in a solid state at room temperature.

Melting point (Celsius)
75.00
Melting point (Kelvin)
348.15
Boiling point (Celsius)
428.00
Boiling point (Kelvin)
701.15
General information
Molecular weight
469.61g/mol
Molar mass
469.6060g/mol
Density
1.1000g/cm3
Appearence

Ebastine is a white to slightly yellowish crystalline powder. It has a characteristic odor and is soluble in common organic solvents like ethanol.

Comment on solubility

Solubility of N,N-diethyl-2-[2-(4-methoxyphenyl)benzimidazol-1-yl]ethanamine

N,N-diethyl-2-[2-(4-methoxyphenyl)benzimidazol-1-yl]ethanamine, often referred to in the literature for its complex structure, displays interesting solubility characteristics that can be influenced by various factors. Understanding its solubility behavior is important, particularly in pharmaceutical development.

Key Factors Influencing Solubility:

  • Polarity: The presence of both the diethyl amine group and the benzimidazole moiety can affect solubility in polar versus non-polar solvents.
  • Interactions: Hydrogen bonding capabilities and dipole-dipole interactions can enhance solubility in specific solvents.
  • Temperature: As with many organic compounds, solubility may increase with temperature, allowing for better dissolution in a solvent.
  • pH Levels: The ionization of the amine group can significantly impact solubility, especially in aqueous solutions.

In summary, while N,N-diethyl-2-[2-(4-methoxyphenyl)benzimidazol-1-yl]ethanamine demonstrates moderate solubility in organic solvents, its behavior in water may be more variable based on pH and temperature conditions. Consequently, for practical applications, conducting solubility tests under specific conditions is essential to fully grasp its potential usability in various formulations.

Interesting facts

N,N-Diethyl-2-[2-(4-methoxyphenyl)benzimidazol-1-yl]ethanamine

This intriguing compound, known as N,N-Diethyl-2-[2-(4-methoxyphenyl)benzimidazol-1-yl]ethanamine, showcases the fascinating world of benzimidazole derivatives, which have garnered significant interest in medicinal chemistry.

Here are some key points about this compound:

  • Potential Applications: Compounds like N,N-diethyl-2-[2-(4-methoxyphenyl)benzimidazol-1-yl]ethanamine are often studied for their potential as antitumor agents, offering a promising avenue for cancer research.
  • Structure-Activity Relationship: The diverse functional groups in this compound enable chemists to explore the relationship between structure and biological activity, paving the way for novel drug design.
  • Mechanism of Action: Research suggests that benzimidazole derivatives may interact with specific biological targets, such as enzymes and receptors, showcasing their potential as therapeutic agents.
  • Natural Occurrence: Interestingly, several naturally occurring compounds share structural characteristics with benzimidazoles, which may influence their biological properties and therapeutic potential.

In the context of drug development, the synthesis and evaluation of compounds like this can provide invaluable insights into new treatment modalities. As the field of pharmaceutical chemistry continues to evolve, compounds like N,N-diethyl-2-[2-(4-methoxyphenyl)benzimidazol-1-yl]ethanamine exemplify the intersection of creativity and science, leading to innovations that could transform patient care.

Synonyms
2-(p-Anisyl)-1-(2-diethylaminoethyl)benzimidazole
5322-99-6
BENZIMIDAZOLE, 1-(2-(DIETHYLAMINO)ETHYL)-2-(p-METHOXYPHENYL)-
1-(2-(Diethylamino)ethyl)-2-(p-methoxyphenyl)benzimidazole
DTXSID90201307
DTXCID50123798