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Orphenadrine

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Identification
Molecular formula
C18H23NO
CAS number
83-98-7
IUPAC name
N,N-diethyl-2-(2-methylphenoxy)ethanamine
State
State

Orphenadrine is typically solid at room temperature.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
361.00
Boiling point (Kelvin)
634.15
General information
Molecular weight
269.39g/mol
Molar mass
269.3850g/mol
Density
1.0052g/cm3
Appearence

Orphenadrine is typically encountered as colorless crystals or a white or almost white crystalline powder. Its appearance is in line with many organic compounds used in pharmaceuticals.

Comment on solubility

Solubility of N,N-Diethyl-2-(2-methylphenoxy)ethanamine

N,N-Diethyl-2-(2-methylphenoxy)ethanamine is an interesting compound with a highly variable solubility profile, largely influenced by its molecular structure. Understanding the solubility characteristics of this compound is vital for its applications in various chemical processes.

Key Factors Influencing Solubility

  • Polarity: The presence of both hydrophobic (diethyl groups) and hydrophilic (ethanamine group) sections results in a balanced polarity.
  • Temperature: Solubility often increases with temperature; thus, heating can enhance its solubility in suitable solvents.
  • Solvent Choice: This compound tends to be more soluble in organic solvents such as ethanol and acetone compared to water due to its hydrophobic components.
  • pH Variability: The solubility can be affected by the pH of the solution, especially since it contains a basic amine group.

In summary, while N,N-diethyl-2-(2-methylphenoxy)ethanamine may exhibit moderate solubility in water, it is significantly more soluble in organic solvents. As a chemical scientist, it is essential to consider both the environmental factors and the solvent compatibility when working with this compound to achieve the best results in laboratory applications.

Interesting facts

Interesting Facts about N,N-Diethyl-2-(2-methylphenoxy)ethanamine

N,N-Diethyl-2-(2-methylphenoxy)ethanamine is an intriguing compound known for its use as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Here are some interesting insights about this compound:

  • Pharmaceutical Relevance: This compound plays a crucial role in the development of medications, often related to neurological and psychiatric conditions. Its structure suggests potential interactions with neurotransmitter receptors, making it a valuable asset in drug discovery.
  • Agrochemical Applications: Beyond pharmaceuticals, N,N-diethyl-2-(2-methylphenoxy)ethanamine is also employed in the formulation of agrochemicals, contributing to the development of herbicides and pesticides that enhance agricultural productivity.
  • Structure-Activity Relationship (SAR): The unique arrangement of the diethyl and aromatic groups in the molecule provides researchers with a fascinating opportunity to study the structure-activity relationships. Understanding how slight modifications to the structure can affect biological activity is critical in medicinal chemistry.
  • Safety and Handling: As with many organic compounds, it is essential to handle this chemical with care. Safety protocols include working in well-ventilated areas and using appropriate personal protective equipment to ensure safe handling.
  • Research Potential: Continuous research into this compound's properties may unveil new therapeutic potentials or applications in materials science, thereby broadening its significance in both academic and industrial fields.

In summary, N,N-diethyl-2-(2-methylphenoxy)ethanamine exemplifies how a relatively obscure organic compound can have far-reaching implications across diverse fields such as medicine and agriculture. Its varied applications and ongoing research ensure its place in the chemistry community.

Synonyms
N,N-diethyl-2-(2-methylphenoxy)ethanamine
CBMicro_020796
Oprea1_707802
SCHEMBL8360708
CCG-8535
AKOS002774500
BIM-0020779.P001
AB00086090-01