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N-Desmethyldiazepam

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Identification
Molecular formula
C15H20N2O2
CAS number
91173-88-5
IUPAC name
N,N-diethyl-2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethanamine
State
State

The compound is in a liquid state at room temperature, exhibiting some viscosity typical of amine derivatives.

Melting point (Celsius)
32.00
Melting point (Kelvin)
305.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
246.33g/mol
Molar mass
246.3050g/mol
Density
1.0200g/cm3
Appearence

N,N-diethyl-2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethanamine typically appears as a colorless to pale yellow liquid. Its specific characteristics can vary depending on the purity and exact formulation of the material.

Comment on solubility

Solubility of N,N-diethyl-2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethanamine

The solubility of N,N-diethyl-2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethanamine can be characterized by several factors influenced by its chemical structure. This compound is moderately soluble in organic solvents but exhibits limited solubility in water. Here are key points to consider:

  • Polar vs. Non-Polar Solvents: The presence of the isoxazole ring and the methoxyphenyl group suggests an interaction with polar solvents, yet its overall hydrophobic alkyl chains may hinder water solubility.
  • Temperature Effects: As with many organic compounds, solubility can increase with temperature, making it more viable in heated organic solutions.
  • pH Influence: The ionic state of the amine group can change with variations in pH, potentially affecting solubility; in acidic conditions, protonation may lead to increased solubility in aqueous environments.

In practice, solubilizing agents or co-solvents might be necessary for effective dissolution, particularly in aqueous formulations. Understanding the solubility profile of this compound is crucial for its applications in drug design and formulation, where optimal bioavailability depends significantly on the solubility characteristics of the compound.

Interesting facts

N,N-Diethyl-2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethanamine

N,N-Diethyl-2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethanamine, often referred to within theoretical and practical realms of chemistry for its intriguing structure and potential applications, is a fascinating compound worth exploring. Here are some interesting points about it:

  • Unique Structure: This compound features an isoxazole ring fused with a phenyl group containing a methoxy substituent, presenting unique chemistry that merits attention for its reactivity and interaction with biological systems.
  • Psychoactive Potential: Compounds with similar structures are often studied in neuropharmacology for their potential effects on the central nervous system. The diethylamine moiety may contribute to activities that modulate neurotransmitter systems.
  • Pharmaceutical Relevance: The structural attributes of N,N-diethyl-2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethanamine allow it to serve as a template in drug design. Researchers often use such compounds to investigate therapeutic potentials, particularly in areas like pain management or mood disorders.
  • Research Applications: This compound can be a valuable target for synthesis in academic and medicinal chemistry laboratories looking to develop new pharmaceuticals or to study the mechanisms of active compounds.
  • Analytical Interest: The complexity of its structure allows for various analytical techniques to be employed, including NMR spectroscopy and mass spectrometry, to investigate its properties and behaviors in different environments.

With such a rich tapestry of potential applications and research opportunities, compounds like N,N-diethyl-2-[3-(4-methoxyphenyl)isoxazol-5-yl]ethanamine not only stimulate the curious minds of chemists but also open avenues for innovative solutions in medicinal chemistry. As stated by renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This sentiment resonates deeply in the exploration of compounds like this one, where every aspect invites further investigation.