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Indofloramine

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Identification
Molecular formula
C14H19FN2
CAS number
856692-99-4
IUPAC name
N,N-diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine
State
State

At room temperature, Indofloramine is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
366.15
Boiling point (Kelvin)
639.30
General information
Molecular weight
246.32g/mol
Molar mass
246.3190g/mol
Density
1.2328g/cm3
Appearence

Indofloramine appears as a solid white to off-white crystalline powder.

Comment on solubility

Solubility of N,N-Diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine

N,N-Diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine, with the chemical formula C14H19FN2, is a compound belonging to the class of amines and indole derivatives. The solubility of this compound can be influenced by several factors:

  • Polarity: Due to its amine functional group and other polar characteristics, N,N-diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine is expected to have some level of polarity, which can enhance its solubility in polar solvents.
  • Hydrogen Bonding: The presence of nitrogen in the amine group allows for potential hydrogen bonding interactions, which can further affect solubility in water and other protic solvents.
  • Alkyl Chains: The diethyl groups contribute hydrophobic characteristics, which may hinder solubility in highly polar solvents but improve solubility in organic solvents.

In summary, while it is likely that N,N-diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine shows better solubility in organic solvents (like ethanol or methanol), it may have limited solubility in water due to its hydrophobic segments. This property is crucial for various applications, as it affects the bioavailability and transport of the compound in biological systems.

Interesting facts

Exploring N,N-Diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine

N,N-Diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine is a fascinating compound that falls within the realm of psychoactive substances. As a chemist or a curious learner, you might find the following aspects of this molecule particularly intriguing:

  • Structural Characteristics:
    This compound features an indole ring, which is a key component in many biologically active compounds. The addition of a fluorine atom enhances its pharmacological properties, making it a subject of interest in medicinal chemistry.
  • Psychoactive Potential:
    The indole structure is related to several well-known psychedelics. Although research on this specific compound is limited, it may exhibit significant effects on the central nervous system, akin to its structural relatives.
  • Fluorine's Role:
    The incorporation of fluorine can lead to increased lipophilicity and metabolic stability. Such modifications often enhance the compound's bioavailability, allowing for more effective interactions within biological systems.
  • Synthetic Pathways:
    The synthesis of this compound involves multiple steps, highlighting the versatility of synthetic organic chemistry. The precise methods utilized can influence yield and purity, critical factors in the study of pharmaceutical compounds.
  • Research Implications:
    Understanding the behaviors of compounds like N,N-diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine can pave the way for new therapeutic strategies, especially in the treatment of mood disorders and other psychological conditions.

As you delve deeper into the world of chemical compounds, remember that each molecule offers a unique story, filled with potential discoveries and applications. The study of N,N-diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine is a perfect example of how chemistry intersects with neuroscience, offering endless possibilities for future research.

Synonyms
6-Fluoro-N,N-diethyltryptamine
2836-69-3
6-Fluorodiethyltryptamine
0ZD2XR6YPV
1H-Indole-3-ethanamine, N,N-diethyl-6-fluoro-
UNII-0ZD2XR6YPV
N,N-Diethyl-6-fluoro-1H-indole-3-ethanamine
UNII-LY55HN88U7
N,N-diethyl-2-(6-fluoro-1H-indol-3-yl)ethanamine
CHEMBL444612
N,N-diethyl-2-(6-fluoro-1H-indol-3-yl)ethan-1-amine
6-FDET; 6-fluoro N,N-DET; ?6-fluoro N,N-Diethyltryptamine
6-Fluor- Diathyltryptamin
DTXSID301345652
BDBM50094672
PD099220
HY-169440
Diethyl-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-amine