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Amitriptyline

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Identification
Molecular formula
C20H23N
CAS number
50-48-6
IUPAC name
N,N-diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]indol-5-yl)ethanamine
State
State

Amitriptyline is typically found in a solid state at room temperature and is often used in various medicinal formats including tablets and capsules.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
391.00
Boiling point (Kelvin)
664.15
General information
Molecular weight
277.41g/mol
Molar mass
277.4140g/mol
Density
1.0075g/cm3
Appearence

Amitriptyline, in its raw form, commonly appears as a white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of N,N-Diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]indol-5-yl)ethanamine

The solubility of N,N-diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]indol-5-yl)ethanamine in different solvents can be a critical factor in its application and utility. The compound presents interesting solubility characteristics that can influence its behavior in various chemical environments. Below are key points regarding its solubility:

  • Solvent Polarity: This compound is likely to show varying solubility depending on the polarity of the solvent used. Generally, non-polar solvents may dissolve such organic compounds better than polar solvents.
  • Aqueous Solubility: Its tendency to dissolve in water may be limited due to its complex structure which could hinder interaction with water molecules, making it less soluble in aqueous solutions.
  • Organic Solvents: It is expected that organic solvents like ethanol, methanol, or chloroform might enhance solubility, allowing the compound to dissolve more readily.
  • Temperature Effect: Increasing the temperature might improve the solubility of this compound in certain solvents by promoting molecular motion.

In summary, while the precise solubility of N,N-diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]indol-5-yl)ethanamine may require experimental verification, understanding solvent interactions and environmental conditions are crucial for its effective utilization.

Interesting facts

Interesting Facts About N,N-Diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]indol-5-yl)ethanamine

N,N-Diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]indol-5-yl)ethanamine, often referred to within scientific communities as a complex amine compound, is a fascinating subject of study in the field of organic chemistry. Here are some intriguing facts about this compound:

  • Structural Complexity: The compound features a unique polycyclic structure, which includes a cyclohepta[b]indole moiety. This type of structure is notable for its implications in medicinal chemistry, as similar compounds often exhibit significant biological activity.
  • Research Interest: Owing to its structural components, N,N-diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]indol-5-yl)ethanamine has garnered attention for potential applications in pharmacology, particularly in psychopharmacology due to its potential interactions with neurotransmitter systems.
  • Pharmacological Properties: Compounds that share structural similarities with this amine have been researched for their effects on the central nervous system. **Preliminary studies** suggest possible uses as mood enhancers and anti-anxiety agents.
  • Synthetic Challenges: The synthesis of such compounds can be quite challenging, requiring careful selection of reagents and conditions to ensure proper formation of the complex ring structure while maintaining high yields.
  • Quote to Remember: As with many similar compounds, "The potency of a compound often lies hidden within its intricate architecture," emphasizing the importance of molecular design in drug development.

This compound not only represents a significant challenge from a synthetic perspective but also holds promise for future applications in various fields including pharmacology and medicinal chemistry. Through ongoing research and exploration, scientists continue to unveil the potential of such unique and complex compounds.