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Antazoline

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Identification
Molecular formula
C17H23NO2
CAS number
91-75-8
IUPAC name
N,N-diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)ethanamine
State
State

At room temperature, Antazoline is typically in a solid state. In its pure form, it is a crystalline powder that can be handled relatively easily. It is often used in a salt form where it may dissolve in water or other solvents.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.20
Boiling point (Celsius)
574.70
Boiling point (Kelvin)
847.90
General information
Molecular weight
293.39g/mol
Molar mass
293.4070g/mol
Density
1.0622g/cm3
Appearence

Antazoline appears as a white or slightly yellowish crystalline powder. It is typically odorless and has a slightly bitter taste. This compound is often used in its hydrochloride salt form for medicinal purposes, where it may present as a fine crystalline powder.

Comment on solubility

Solubility of N,N-Diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)ethanamine

The solubility of N,N-diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)ethanamine can be influenced by several factors, making it an intriguing compound to study. The intricate structure plays a significant role in determining its solubility characteristics. Below are some key points to consider:

  • Polarity: The presence of polar groups in the molecule tends to increase solubility in polar solvents, whereas non-polar regions can facilitate solubility in non-polar solvents.
  • Hydrogen Bonding: If the compound can form hydrogen bonds, it may show increased solubility in water.
  • Temperature: Solubility can often increase with temperature, making heat a crucial factor in dissolution.
  • pH Dependence: The solubility may vary with changes in pH, especially for amines, which can become protonated and change their solubility profile.

It is important to note that the solubility of this compound in common solvents has not been extensively documented. Experimental evaluations are essential to fully understand the solubility behavior of this unique chemical entity. As such, it becomes imperative to conduct solubility testing in various conditions to achieve a detailed understanding:

  1. Testing in aqueous solutions to ascertain water solubility.
  2. Experimenting with organic solvents to determine non-polar solubility.
  3. Assessing the impact of additives that may aid in solubilization.

In summary, the solubility of N,N-diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)ethanamine remains a subject of research interest, inviting further experimentation and study.

Interesting facts

Exploring N,N-Diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)ethanamine

N,N-Diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)ethanamine, a compound with a fascinating structure, is of considerable interest in the field of medicinal chemistry. This compound is characterized by its complex bicyclic structure, which includes elements typical of quinoline derivatives.

Key Facts:

  • Versatility in Applications: This compound has potential applications in the development of pharmaceuticals, particularly in treating neurodegenerative diseases due to its structural properties that may enhance interactions with neurological targets.
  • Structure-Activity Relationship (SAR): The unique cyclohepta[b]quinoline ring system may provide insights into the relationship between molecular structure and biological activity. Understanding the SAR can guide modifications that enhance efficacy and reduce side effects.
  • Research and Development: Ongoing research in synthetic and medicinal chemistry often focuses on compounds like this to discover novel therapeutic agents. Investigating analogs and derivatives can lead to breakthroughs in new drug development.
  • Interesting Functional Groups: The presence of diethylamine and ether functionalities creates potential for diverse interactions, influencing both solubility and reactivity, which are critical in drug design.

This compound exemplifies the intricate balance of molecular complexity and biological relevance, highlighting the importance of structural variety in drug design. As researchers continue to explore compounds like N,N-diethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)ethanamine, the hope for innovative treatments becomes increasingly tangible.