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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N,N-diethyl-4-hydroxy-3-methoxy-benzamide
State
State

At room temperature, Lidocaine is typically in a solid state.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
221.30g/mol
Molar mass
221.2970g/mol
Density
1.0990g/cm3
Appearence

Lidocaine appears as a white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of N,N-diethyl-4-hydroxy-3-methoxy-benzamide

N,N-diethyl-4-hydroxy-3-methoxy-benzamide, characterized by its unique structure, displays interesting solubility properties that can be crucial for its applications.

Generally, the solubility of this compound can be influenced by several factors:

  • Polarity: The presence of both the diethylamine and the hydroxy group tends to increase polarity, potentially enhancing solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxy group (-OH) can engage in hydrogen bonding, making the compound more soluble in protic solvents.
  • Solvent Interaction: As a benzamide derivative, N,N-diethyl-4-hydroxy-3-methoxy-benzamide may exhibit good solubility in organic solvents such as ethanol and methanol.
  • Temperature Effect: Increasing temperature often increases the solubility of organic compounds, suggesting that elevated temperatures may favor solubility in suitable solvents.

Overall, while the exact solubility values can vary based on conditions, it is important to note that “the solubility of a compound is a crucial aspect of its behavior and utility in different chemical environments.” Understanding its solubility can guide researchers and practitioners in selecting appropriate solvents for reactions, formulations, or extractions.

Interesting facts

Interesting Facts about N,N-Diethyl-4-hydroxy-3-methoxy-benzamide

N,N-Diethyl-4-hydroxy-3-methoxy-benzamide, often referred to in scientific discussions as DEHMB, is a compound that showcases the fascinating interplay between organic chemistry and pharmacology. Here are some intriguing insights into this compound:

  • Structure and Function: The molecular design of DEHMB features a benzamide backbone with modifications that enhance its biological activity. The presence of both hydroxy and methoxy groups allows for unique interactions with biological receptors.
  • Pharmacological Potential: Compounds like DEHMB are often investigated for their potential therapeutic properties. They may exhibit a range of biological activities, including anti-inflammatory and analgesic effects.
  • Synthetic Routes: From a synthetic perspective, the preparation of DEHMB involves classic organic reactions. Chemists may utilize intermediates from simpler compounds to construct its complex structure, making it a valuable teaching case in synthesis labs.
  • Applications in Research: DEHMB serves as a versatile reagent in various studies, helping researchers to explore the mechanisms of drug action and improve drug formulation. Its modification of the benzamide framework allows for numerous derivatives to be synthesized.
  • Safety and Handling: As with many organic compounds, proper safety precautions must be followed when handling DEHMB. Understanding its toxicological profile is crucial for ensuring safe use in laboratory settings.

This compound not only highlights the beauty of molecular structure but also emphasizes the significance of functional groups in dictating the behavior of chemical substances. As research progresses, compounds like N,N-diethyl-4-hydroxy-3-methoxy-benzamide may unveil new pathways for drug discovery and innovative therapeutic solutions.

Synonyms
ETHAMIVAN
Etamivan
Vanillic acid diethylamide
304-84-7
Emivan
Vandid
Analepticon
Etamivanum
Simaron
N,N-Diethylvanillamide
Cardiovanil
Corivanil
Diethamivan
Diethylvanillamide
Ventilone
Romecor
Sevanil
Benzamide, N,N-diethyl-4-hydroxy-3-methoxy-
N,N-Diethyl-4-hydroxy-3-methoxybenzamide
Cardiovamil
Sevinal
Diethylamide de vanillique
Vanillic acid N,N-diethylamide
Vanillinsaeure-diaethylamid
Etamivan [INN]
Vanillamide, N,N-diethyl-
3-Methoxy-4-hydroxybenzoic acid diethylamide
Clairvan
NSC-406087
M44O63YPV9
DTXSID3023007
ETHAMIVAN [MI]
ETHAMIVAN [USAN]
NSC406087
ETAMIVAN [MART.]
ETAMIVAN [WHO-DD]
MLS000028445
N,N-diethyl-4-hydroxy-3-methoxy-benzamide
DTXCID103007
Ethamivan;N,N-Diethylvanillamide
CHEBI:92675
2-METHYL-4-DIETHYLAMIDE-PHENOL
NCGC00015397-02
NCGC00015397-06
CAS-304-84-7
SMR000058359
ETAMIVAN (MART.)
Etamivanum [INN-Latin]
SR-01000003047
Ethamivan [USAN:USP]
Vanillinsaeure-diaethylamid [German]
EINECS 206-157-3
NSC 406087
BRN 2694478
UNII-M44O63YPV9
AI3-20163
2xdl
Prestwick_909
Vandid (TN)
Vanillamide,N-diethyl-
N, N-Diethylvanillamide
Opera_ID_522
Ethamivan (USAN/INN)
Prestwick0_000500
Prestwick1_000500
Prestwick2_000500
Prestwick3_000500
Lopac-E-0137
Lopac0_000459
BSPBio_000399
4-10-00-01481 (Beilstein Handbook Reference)
MLS001146918
SCHEMBL119823
SPBio_002320
BPBio1_000439
CHEMBL1229908
vanillic acid N,N-diethyl amide
R07AB04
HMS1569D21
HMS2094A19
HMS2096D21
HMS2231D12
HMS3261K20
HMS3369J14
HMS3713D21
Pharmakon1600-01505994
HY-B1096
Tox21_110135
Tox21_110136
Tox21_500459
WLN: 2N2 & VR DQ CO1
BDBM50482752
NSC759302
AKOS003382844
Tox21_110135_1
CCG-204551
CS-4684
DB08989
LP00459
NSC-759302
SDCCGSBI-0050444.P003
NCGC00015397-01
NCGC00015397-03
NCGC00015397-04
NCGC00015397-05
NCGC00015397-07
NCGC00015397-08
NCGC00015397-10
NCGC00015397-15
NCGC00023704-03
NCGC00023704-04
NCGC00261144-01
BP-12587
MS-23252
Benzamide,N-diethyl-4-hydroxy-3-methoxy-
SBI-0050444.P002
DB-047788
EU-0100459
N,N-Diethyl-4-hydroxy-3-methoxybenzamide #
NS00002944
N,N-diethyl-4-hydroxy-3-(methyloxy)benzamide
D04080
E 0137
F85239
EN300-7522809
Q5402414
SR-01000003047-2
SR-01000003047-5
BRD-K38055836-001-03-9
BRD-K38055836-001-21-1
206-157-3
2DL