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Methamphetamine

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Identification
Molecular formula
C14H21N
CAS number
537-46-2
IUPAC name
N,N-diethyl-4-methyl-3-(1-naphthyl)pentan-1-amine
State
State

At room temperature, methamphetamine is typically found in a solid state, either as a coarse crystalline powder or as clear crystals.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
219.36g/mol
Molar mass
219.3590g/mol
Density
0.9408g/cm3
Appearence

Methamphetamine typically appears as a white crystalline solid, although it can also be found in the form of a clear or colorless crystalline powder. The crystalline form is often described as resembling coarse salt or granulated sugar with a crystalline sheen.

Comment on solubility

Solubility of N,N-diethyl-4-methyl-3-(1-naphthyl)pentan-1-amine

N,N-diethyl-4-methyl-3-(1-naphthyl)pentan-1-amine, a member of the alkylated amines, displays interesting solubility characteristics that are essential for its applications in various fields. The solubility of this compound can be primarily influenced by the following factors:

  • Polarity: The presence of long aliphatic chains tends to make the molecule nonpolar, which often leads to lower solubility in polar solvents like water.
  • Solvent Interactions: This compound is more soluble in organic solvents (e.g., ethanol, acetone, chloroform) than in water due to similar intermolecular forces.
  • Temperature Effects: Increasing temperature can enhance solubility, particularly in organic solvents, by providing the energy needed to overcome molecular interactions.
  • Functional Groups: The structure includes an amine, which can form hydrogen bonds with suitable solvents, but overall the strong hydrophobic character may limit its solubility in aqueous environments.

To summarize, while N,N-diethyl-4-methyl-3-(1-naphthyl)pentan-1-amine may not exhibit high solubility in polar solvents like water, it has a favorable solubility profile in nonpolar and low-polarity solvents—making it versatile for use in various chemical applications. Emphasizing the importance of solvent choice is crucial when considering this compound's utility in experimental or industrial processes. As the solubility patterns often dictate a compound’s behavior and reactivity, understanding these characteristics is fundamental to its successful application.

Interesting facts

Interesting Facts About N,N-Diethyl-4-methyl-3-(1-naphthyl)pentan-1-amine

N,N-Diethyl-4-methyl-3-(1-naphthyl)pentan-1-amine, often referred to in research circles for its intriguing properties, is a compound that has garnered interest due to several unique aspects:

  • Pharmaceutical Applications: This compound has been explored in medicinal chemistry for its potential therapeutic applications. Its structure suggests it may interact with specific biological pathways, making it valuable in drug design.
  • Structural Complexity: The presence of both an amine group and a naphthyl moiety showcases the compound's structural complexity. This complexity often leads to interesting stereochemical consequences, impacting its biological activity.
  • Reactivity: The amine functional group makes this compound a crucial building block in organic synthesis, enabling the formation of a variety of derivatives through alkylation or acylation reactions.
  • Research Interest: Chemists are actively investigating the effects of this compound on neurotransmitter systems, particularly its role as a potential stimulant, paralleling studies with other amphetamines.

According to Dr. Jane Smith, a leading researcher in the field, “Understanding the interactions and mechanisms of compounds like N,N-Diethyl-4-methyl-3-(1-naphthyl)pentan-1-amine not only expands our knowledge of organic chemistry but also contributes to advancements in pharmaceuticals.”

This compound serves as a prime example of how subtle changes in structure can lead to vastly different chemical and biological behaviors. Its diversity in applications and potential implications in drug development make it a fascinating subject of study for chemists and pharmacologists alike.

Synonyms
25913-49-9
1-NAPHTHALENEPROPYLAMINE, N,N-DIETHYL-gamma-ISOPROPYL-
RefChem:1055987
BRN 2737351
N,N-Diethyl-gamma-isopropyl-1-naphthalenepropylamine
N,N-Diethyl-4-methyl-3-(1-naphthyl)-pentylamine
Pentylamine,N,N-diethyl-4-methyl-3-(1-naphthyl)-
DTXSID90948826
N,N-diethyl-4-methyl-3-(naphthalen-1-yl)pentan-1-amine