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Diethylpropion hydrochloride

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Identification
Molecular formula
C13H19ClNOS
CAS number
134-80-5
IUPAC name
N,N-diethyl-4,4-bis(2-thienyl)but-3-en-2-amine;hydrochloride
State
State

At room temperature, diethylpropion hydrochloride is in a solid state. It is often used in its crystalline form for pharmaceutical preparations.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
296.81g/mol
Molar mass
294.8330g/mol
Density
1.1185g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder. It is hygroscopic and should be stored in airtight containers to prevent moisture uptake.

Comment on solubility

Solubility of N,N-Diethyl-4,4-bis(2-thienyl)but-3-en-2-amine Hydrochloride

The solubility of N,N-diethyl-4,4-bis(2-thienyl)but-3-en-2-amine hydrochloride can be understood through its chemical structure and properties. This compound, being a hydrochloride salt, typically exhibits higher solubility in polar solvents compared to its free base form. Here are several key points to consider:

  • Water Solubility: Hydrochloride salts generally show good solubility in water due to their ionic nature which facilitates interaction with water molecules.
  • Solvent Interaction: The presence of thienyl groups may affect solubility in organic solvents, where the compound could exhibit distinct solubility profiles influenced by polarity.
  • Temperature Effects: The solubility may increase with temperature; therefore, heating solutions may lead to higher dissolving rates.
  • pH Influence: As a hydrochloride, the compound's solubility can also be affected by the pH of the solution, potentially altering its ionization state and thus modifying solubility characteristics.

Understanding the solubility parameters of N,N-diethyl-4,4-bis(2-thienyl)but-3-en-2-amine hydrochloride is crucial for applications in various fields, including pharmaceuticals, where optimal bioavailability often relies heavily on solubility properties. As highlighted, factors such as solvent choice, temperature, and pH can all play significant roles in the solubility behavior of this compound.

Interesting facts

Interesting Facts about N,N-Diethyl-4,4-bis(2-thienyl)but-3-en-2-amine; hydrochloride

N,N-diethyl-4,4-bis(2-thienyl)but-3-en-2-amine; hydrochloride is a fascinating compound that showcases the complexity and diversity found in organic chemistry. Here are some intriguing aspects of this compound:

  • Medicinal Chemistry: This compound has garnered attention for its potential applications in medicinal chemistry due to its unique structural properties, which can influence biological activity.
  • Thienyl Groups: The presence of 2-thienyl substituents enhances the compound’s electronic characteristics, making it advantageous for photonic and electronic applications.
  • Amine Functionality: The primary amine functional group in its structure serves as a versatile site for further chemical modifications, which can tailor its activity for specific purposes.
  • Biological Relevance: Compounds containing thienyl moieties are often studied for their biological relevance, and may exhibit varied pharmacological prospects, including anti-cancer and anti-inflammatory activities.
  • Research Interest: This hydrochloride salt form not only increases the solubility of the compound but may also affect its bioavailability, making it a key focus in drug formulation research.

In addition to its physical and chemical properties, the exploration of N,N-diethyl-4,4-bis(2-thienyl)but-3-en-2-amine; hydrochloride serves as a reflection of the intricate relationship between molecular structure and function, a core principle in the field of chemistry. Its diverse applications can open new avenues for research and development in pharmaceuticals and materials science.

Synonyms
Diethylthiambutene hydrochloride
132-19-4
3L46E90B1X
Themalon hydrochloride
N,N-diethyl-4,4-dithiophen-2-ylbut-3-en-2-amine;hydrochloride
Di(ethyl)(1-methyl-3,3-di(thien-2-yl)allyl)ammonium chloride
Diethibutin hydrochloride
Thiambutene HCl
NIH 4185
EINECS 205-050-9
UNII-3L46E90B1X
3-Diethylamino-1,1-di(2'-thienyl)but-1-ene hydrochloride
DTXSID50927490
AOBYZQVXPIBGCZ-UHFFFAOYSA-N
3-Buten-2-amine, N,N-diethyl-4,4-di-2-thienyl-, hydrochloride
N,N-Diethyl-1-methyl-3,3-di-2-thienylallylamine hydrochloride
ALLYLAMINE, N,N-DIETHYL-3,3-DI-2-THIENYL-1-METHYL-, HYDROCHLORIDE
FT28198
Q27257478
3-BUTEN-2-AMINE, N,N-DIETHYL-4,4-DI-2-THIENYL-, HYDROCHLORIDE (1:1)
N,N-Diethyl-4,4-di(thiophen-2-yl)but-3-en-2-amine--hydrogen chloride (1/1)
N,N-Diethyl-4,4-di-2-thienyl-3-buten-2-amine hydrochloride;Diethylthiambutene hydrochloride;NIH 4185