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N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide

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Identification
Molecular formula
C15H19NO3
CAS number
189135-06-2
IUPAC name
N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide
State
State

At room temperature, it remains in a solid state, usually exhibiting a crystalline form which may also appear as a fine powder.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.20
Boiling point (Celsius)
465.20
Boiling point (Kelvin)
738.40
General information
Molecular weight
261.32g/mol
Molar mass
261.3170g/mol
Density
1.0870g/cm3
Appearence

The compound is most commonly found as a crystalline solid with a slightly beige hue. It can also appear as a white powder, depending on the specific synthesis method.

Comment on solubility

Solubility of N,N-Diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide

The solubility of N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide in various solvents can greatly influence its applications and behavior in chemical processes. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is typically more soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) than in aqueous solutions due to its non-polar characteristics.
  • Polarity Considerations: The presence of the phenyl group and the carboxamide moiety contributes to its overall polarity, which plays a significant role in solubility behavior. While carboxamides are generally polar, the bulky diethyl group can hinder solvation.
  • Temperature Effects: Increased temperature may enhance the dissolution of this compound in organic solvents, leading to higher solubility rates.
  • Applications: Understanding its solubility is essential for effectively utilizing this compound in pharmaceuticals, where solubility directly impacts bioavailability and therapeutic efficacy.

In summary, the solubility of N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide demonstrates a complex interplay between its structural features and solvating environment. Therefore, careful consideration of these factors is paramount when working with this compound!

Interesting facts

Interesting Facts About N,N-Diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide

N,N-Diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide is a fascinating compound with various intriguing properties and applications in the field of chemistry. Here are some noteworthy points:

  • Synthetic Versatility: This compound is notable for its role as a precursor in organic synthesis, particularly in the field of pharmaceuticals where it can lead to the formation of biologically active molecules.
  • Pharmacological Potential: Due to its intricate structure, N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide has attracted attention for potential medicinal applications. Its derivatives may exhibit various biological activities, making it a subject of research in drug design.
  • Chiral Properties: The compound contains multiple stereocenters, which opens avenues for chiral chemistry. This can be significant in the development of enantiomerically pure compounds that are essential for drug activity.
  • Functional Group Diversity: The presence of both a carboxamide and a ketone in its structure provides unique opportunities for reactivity. These functional groups allow for diversification through various chemical transformations, including reactions with nucleophiles and electrophiles.
  • Mechanistic Insights: Studying the reactions involving this compound can shed light on reaction mechanisms in organic chemistry, helping students and researchers understand complex reactivity patterns.
  • Solvent Interactions: The solubility and interactions with solvents can significantly influence its reactions, offering practical insights into solvent effects in organic reactions.

In conclusion, N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-2-carboxamide is more than just a chemical name; it represents a wealth of opportunities for research and application in various fields, especially medicinal chemistry. As stated by renowned chemists, "Every compound has a story to tell," and this one is no exception.

Synonyms
N,N-Diethyl-5-oxo-2-phenyltetrahydro-2-furamide
13390-02-8
2-FURAMIDE, TETRAHYDRO-N,N-DIETHYL-5-OXO-2-PHENYL-
N,N-diethyl-5-oxo-2-phenyloxolane-2-carboxamide
DTXSID60928332