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N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide

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Identification
Molecular formula
C15H19NO3
CAS number
21240-30-8
IUPAC name
N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide
State
State

At room temperature, N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide is a solid. It is not volatile under standard conditions and should be stored away from moisture and light to maintain its stability.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
261.33g/mol
Molar mass
261.3130g/mol
Density
0.9700g/cm3
Appearence

This compound appears as a solid with a crystalline structure, often taking a white to off-white color.

Comment on solubility

Solubility of N,N-Diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide

The solubility of N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide in various solvents is influenced by its unique chemical structure. This compound features a tetrahydrofuran ring, which contributes to its solubility characteristics.

Key Factors Affecting Solubility:

  • Polarity: The presence of both amide and carbonyl functional groups enhances polarity, which can improve solubility in polar solvents.
  • Hydrogen Bonding: The amide group can engage in hydrogen bonding, allowing solubility in protic solvents like water and alcohols.
  • Hydrophobic Interactions: The phenyl group presents a non-polar character, potentially limiting solubility in pure polar solvents but enhancing it in mixed solvent systems.

In practical terms, the compound is expected to be soluble in solvent systems that balance both polar and non-polar characteristics, making it more amenable to organic solvents with similar properties. Overall, understanding the interplay of these various factors is crucial for predicting and maximizing the solubility of N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide in various applications.

Interesting facts

Interesting Facts About N,N-Diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide

N,N-Diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide is a fascinating compound that showcases the intricate nature of organic chemistry. It belongs to the class of amides, which are essential in various biological processes and industrial applications. Here are some compelling aspects of this compound:

  • Pharmaceutical Potential: Compounds like N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide are often explored for their potential therapeutic properties. Researchers investigate such molecules for roles in drug synthesis and development, particularly owing to the versatility provided by the tetrahydrofuran ring.
  • Structural Complexity: The structure of this compound is particularly interesting due to its multiple functional groups, including an amide and a carbonyl. The presence of the phenyl group adds to its reactivity and can influence its interactions with biological targets.
  • Applications in Material Science: Beyond pharmaceuticals, derivatives of tetrahydrofuran are sometimes utilized in the manufacture of polymers and solvents. Their chemical properties often make them suitable for creating advanced materials.
  • In-depth Studies: Scientists are continuously studying similar compounds to understand their mechanisms of action, metabolism, and toxicity. This could lead to new insights in medicinal chemistry and improve drug discovery processes.

In summary, N,N-diethyl-5-oxo-2-phenyl-tetrahydrofuran-3-carboxamide exemplifies the rich tapestry of organic compounds. Its combination of structural features, potential applications in pharmaceuticals, and the ongoing research surrounding its characteristics make it a noteworthy subject in the field of chemistry.

Synonyms
N,N-Diethyl-5-oxo-2-phenyltetrahydro-3-furamide
N,N-diethyl-5-oxo-2-phenyloxolane-3-carboxamide
13390-03-9
3-FURAMIDE, TETRAHYDRO-N,N-DIETHYL-5-OXO-2-PHENYL-
Oprea1_437616
DTXSID20928333
AB00073723-01