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Lysergic acid diethylamide

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Identification
Molecular formula
C20H25N3O
CAS number
50-37-3
IUPAC name
N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
State
State

At room temperature, lysergic acid diethylamide is generally in a solid state. However, due to its common form of distribution for usage, it is often encountered in a liquid state when diluted or on blotter paper.

Melting point (Celsius)
80.50
Melting point (Kelvin)
353.65
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
323.45g/mol
Molar mass
323.4500g/mol
Density
1.2000g/cm3
Appearence

Lysergic acid diethylamide is typically found as a colorless, odorless, and tasteless crystalline substance when in its pure form. However, it is often distributed on blotter paper or in liquid form, which may be colored or have an odor due to other substances.

Comment on solubility

Solubility of N,N-Diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide, with the chemical formula C20H25N3O, presents intriguing characteristics regarding its solubility. As a complex organic compound, its solubility can be influenced by various factors:

  • Polarity: The presence of multiple functional groups in the structure may contribute to a certain degree of polarity, which affects solubility in polar versus non-polar solvents.
  • Hydrogen Bonding: The carboxamide moiety can engage in hydrogen bonding, influencing its ability to dissolve in aqueous solutions.
  • Solvent Dependency: This compound is likely to demonstrate varied solubility in different solvents, being more soluble in organic solvents such as dimethyl sulfoxide (DMSO) compared to water.

In general, compounds with large, complex structures such as this one often exhibit poor solubility in water while being more soluble in organic solvents. As a result, it is crucial to consider the application and environment in which this compound is used to optimize its solubility for specific purposes. Further studies on solubility enhancement techniques could lead to improved applicability in pharmaceuticals or chemical processes.

Interesting facts

Interesting Facts about N,N-Diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

N,N-Diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide is a fascinating compound with a range of intriguing properties and potential applications. Here are some key aspects to consider:

  • Complex Structure: This compound features an intricate molecular structure, which includes a fused indole and quinoline system, providing a unique aromatic character that could contribute to its biological activity.
  • Biological Relevance: Compounds of this class have been studied for their potential pharmacological effects. There is significant interest in indoloquinoline derivatives for their potential as therapeutic agents in treating various health conditions, including cancer.
  • Rational Design: The incorporation of diethyl groups and a methyl substituent suggests that the compound may exhibit enhanced lipophilicity, which is often advantageous in drug design as it may facilitate better membrane permeability and bioavailability.
  • Diversity of Applications: Beyond pharmacology, the properties of this compound could be explored in fields such as materials science, medicinal chemistry, and organic synthesis, owing to its distinctive structure.
  • Research Potential: Given its complex architecture, the compound presents numerous avenues for research. Future studies could investigate mechanisms of action, synthesis pathways, and modifications to further optimize its efficacy.

Understanding compounds like N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide not only enhances our knowledge of organic chemistry but also expands the horizon for innovations in medicinal and applied sciences. As scientists delve deeper into its properties, this compound may unveil more fascinating characteristics, promising exciting advancements in various interdisciplinary fields.

Synonyms
D-Lysergic acid N,N-diethylamide
(+)-Lysergide-d3
(+)-LSD
Lysergsaure diethylamid
d-Lysergic acid dethylamide
Indolo[4,3-fg]quinoline, ergoline-8-carboxamide deriv.
Lysergsaure-N,N-diethylamid
D-LSD-25
CHEMBL4764888
SCHEMBL12401704
BDBM86427
CHEBI:182684
VAYOSLLFUXYJDT-UHFFFAOYSA-N
CAA12678
LFA76538
NSC_3981
CAS_50-37-3
L000352
9,10-Didehydro-N,N-diethyl-6-methyl-ergoline-8-.beta.-carboxamide
Ergoline-8.beta.-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-
Ergoline-8-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-, (8.beta.)-
N,N-Diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, (8.beta.)- #
N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-g]quinoline-9-carboxamide