Skip to main content

Mitoxantrone

ADVERTISEMENT
Identification
Molecular formula
C22H28N4O6
CAS number
65271-80-9
IUPAC name
N',N'-diethyl-N-(1-nitroacridin-9-yl)ethane-1,2-diamine
State
State

At room temperature, Mitoxantrone is a solid. It is used in clinical settings mostly in liquid formulation within medical settings for its efficacy as a chemotherapeutic agent.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
726.10
Boiling point (Kelvin)
999.30
General information
Molecular weight
444.49g/mol
Molar mass
444.5310g/mol
Density
1.4600g/cm3
Appearence

Mitoxantrone is typically a dark blue crystalline solid, often appearing in powdered formulations for clinical use. It is notable for its deep coloration, which is characteristic of many anthracenedione antibiotics.

Comment on solubility

Solubility of N',N'-diethyl-N-(1-nitroacridin-9-yl)ethane-1,2-diamine

N',N'-diethyl-N-(1-nitroacridin-9-yl)ethane-1,2-diamine is a complex organic compound that exhibits a noteworthy solubility profile. Understanding its solubility is crucial for various applications in both research and industrial settings.

Key aspects of the solubility of this compound include:

  • Polar Character: The presence of the amino groups within the ethane backbone can contribute significantly to its solubility in polar solvents. Compounds with similar functionalities often dissolve well in water or methanol, although specific solubility tests should be conducted for precise data.
  • Nonpolar Components: On the other hand, the nitroacridine moiety adds a degree of hydrophobic character, potentially limiting solubility in highly polar environments. "Like dissolves like" is a guiding principle here; thus, this compound may find better solubility in organic solvents such as DMSO or acetone.
  • Temperature Influence: Solubility can also be affected by temperature, where higher temperatures might lead to increased solubility in many solvents.

Due to the molecular structure and the presence of multiple functional groups, the solubility behavior of N',N'-diethyl-N-(1-nitroacridin-9-yl)ethane-1,2-diamine warrants careful examination. Experimental determination of solubility in various media is recommended to gain comprehensive insights into its practical utility.

Interesting facts

Interesting Facts About N',N'-diethyl-N-(1-nitroacridin-9-yl)ethane-1,2-diamine

N',N'-diethyl-N-(1-nitroacridin-9-yl)ethane-1,2-diamine is a fascinating compound that merges elements of organic chemistry with unique properties and potential applications. Here are some intriguing facts worth noting:

  • Structure and Composition: The compound features a complex structure that includes both an acridine moiety and an ethane diamine segment. This combination contributes to its biological activity and interaction with other molecules.
  • Biological Relevance: Compounds like this one are often studied for their potential as anticancer agents, particularly due to the presence of the nitro group which can enhance biological activity.
  • Fluorescent Properties: The acridine scaffold is known for its fluorescence, which can be exploited in various analytical techniques and in the development of fluorescence-based sensors.
  • Synthesis Challenges: The synthesis of this compound involves multi-step reactions, which can present challenges in terms of yield and purity. Each step requires careful optimization to achieve high-quality products.
  • Research Applications: Researchers are actively exploring the mechanisms of action for such compounds in cellular environments, which may lead to groundbreaking discoveries in medicinal chemistry.

In summary, N',N'-diethyl-N-(1-nitroacridin-9-yl)ethane-1,2-diamine exemplifies the intersection of structural complexity and biological activity, making it a compound of great interest in both academic and industrial chemistry.

Synonyms
NCI60_015696
CHEMBL2009054