Skip to main content

Naphazoline

ADVERTISEMENT
Identification
Molecular formula
C16H24N2O
CAS number
835-31-4
IUPAC name
N',N'-diethyl-N-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine
State
State

At room temperature, Naphazoline is a solid, typically encountered in a crystalline powder form. Due to its use in eye drops, it is also prevalent in liquid solution formulations.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
310.48g/mol
Molar mass
310.4640g/mol
Density
1.0400g/cm3
Appearence

Naphazoline typically appears as a white to practically white crystalline powder. It is often available in solution form for use in ophthalmic preparations. The powder is crystalline in structure, highlighting its purity and suitability for pharmaceutical formulations.

Comment on solubility

Solubility of N',N'-diethyl-N-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine

The solubility characteristics of N',N'-diethyl-N-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine (C16H24N2O) are an intriguing aspect of its chemical behavior. Understanding its solubility can provide essential insights into its potential applications and interactions in various environments. Here are several key points to consider:

  • Polarity: The presence of amine functional groups often contributes to the polar nature of the compound, which can enhance solubility in polar solvents such as water.
  • Nonpolar Characteristics: The bulky naphthalene and tetrahydrofuran moieties may impart some nonpolar characteristics, suggesting lower solubility in polar solvents.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents like ethanol or chloroform, where the hydrophobic regions can interact favorably.
  • Temperature Effects: Temperature changes can affect solubility; typically, increased temperature enhances the solubility of solid solutes in liquids.

In summary, while N',N'-diethyl-N-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine is expected to demonstrate moderate solubility profiles across different mediums, further experimental data would be essential for precise delineation of its solubility behaviors under various conditions.

Interesting facts

Interesting Facts About N',N'-diethyl-N-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine

N',N'-diethyl-N-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine is a fascinating compound due to its unique structural components and potential applications. Here are some noteworthy facts:

  • Hybrid Structure: This compound features a hybrid structure, combining a naphthyl group with a tetrahydrofuran moiety. The integration of these two distinct organic structures contributes to its interesting chemical properties.
  • Potential Medicinal Uses: Compounds containing tetrahydrofuran and amine functionalities are often explored for their potential therapeutic benefits. This compound may have implications in drug development, particularly due to its structural similarity to biologically active molecules.
  • Chirality: The presence of multiple chiral centers in this molecule could result in enantiomers with different biological activities. This characteristic necessitates careful consideration during research and synthesis.
  • Research Opportunities: As a relatively complex molecule, N',N'-diethyl-N-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine presents significant opportunities for research in the fields of synthetic chemistry and pharmacology.
  • Impact of Substituents: The naphthyl group can significantly influence the compound’s electronic and steric properties, which may enhance its interactions with other biological molecules, making it an interesting candidate for further exploration.

In summary, N',N'-diethyl-N-[2-(1-naphthyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine stands as a compound of great interest in both academic and research settings, encouraging scientists to delve deeper into its characteristics and potential applications.