Ebastine | Solubility of Things

Identification

Molecular formula

C₃₂H₃₉NO₂

CAS number

90729-43-4

IUPAC name

N',N'-diethyl-N-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine

State

Ebastine is typically found in its solid state as a powder at room temperature. It is stable under normal conditions and is used as an active pharmaceutical ingredient in antihistamines.

Melting point (Celsius)

124.00

Melting point (Kelvin)

397.15

Boiling point (Celsius)

493.15

Boiling point (Kelvin)

766.15

General information

Molecular weight

469.64g/mol

Molar mass

469.6430g/mol

Density

1.0203g/cm³

Appearence

Ebastine is a white to off-white crystalline powder. It is practically insoluble in water, soluble in organic solvents like ethanol or methanol, and freely soluble in acetone.

Comment on solubility

Solubility of N',N'-diethyl-N-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine

The solubility of the compound N',N'-diethyl-N-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine (C₃₂H₃₉NO₂) is influenced by several factors, making it a fascinating subject of study. Considering its complex molecular structure, the solubility can be summarized as follows:

Polarity: The presence of polar functional groups, such as amines and ethers, suggests that the compound may exhibit some degree of solubility in polar solvents like water and alcohols.
Non-polar characteristics: With a significant hydrophobic naphthyl group, solubility in non-polar solvents such as hydrocarbons is likely enhanced.
Temperature Dependence: As with many organic compounds, solubility can be temperature-dependent; higher temperatures often increase solubility in liquids.
pH Influence: The solubility of amines can vary with pH, where increases in acidity may promote protonation, leading to greater water solubility.

In summary, one might say, "solubility is not just a number, but a complex interplay of molecular forces." Understanding the solubility of C₃₂H₃₉NO₂ can provide valuable insights into its applications and behavior in various environments.

Interesting facts

Interesting Facts about N',N'-diethyl-N-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine

N',N'-diethyl-N-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine is a fascinating compound that belongs to a group of molecules considered important in medicinal chemistry and drug design. Here are some intriguing aspects of this complex chemical:

Diverse Structure: The compound features a unique combination of naphthalene and tetrahydrofuran, allowing it to interact with biological systems in intricate ways.
Pharmacological Potential: Due to its structural complexity, compounds like this are often investigated for their potential as therapeutic agents, particularly in treating neurological or psychological disorders.
Synthetic Challenges: The synthesis of such compounds can be quite demanding, requiring advanced organic chemistry techniques to ensure the correct stereochemistry and functional groups are incorporated, which can greatly influence biological activity.
Research Applications: Compounds of this nature are frequently used in medicinal chemistry research, where scientists explore their interactions with various targets, potentially leading to the development of new pharmaceutical agents.

In the words of a renowned chemist, "The beauty of organic synthesis lies not just in the final product, but in the journey of creating complex structures that may hold the key to novel therapies." This compound exemplifies such a journey.

Ultimately, N',N'-diethyl-N-[2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propyl]ethane-1,2-diamine is more than just a molecule; it represents the intersection of creativity and science in the quest for new medicinal therapies.