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Etodolac

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Identification
Molecular formula
C17H21N2O2
CAS number
41340-25-4
IUPAC name
N',N'-diethyl-N-[2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethyl]ethane-1,2-diamine
State
State

At room temperature, Etodolac is in a solid state. It is stable under normal conditions and has a high melting point, characteristic of its solid nature as a compound.

Melting point (Celsius)
145.50
Melting point (Kelvin)
418.70
Boiling point (Celsius)
484.20
Boiling point (Kelvin)
757.40
General information
Molecular weight
287.37g/mol
Molar mass
287.3660g/mol
Density
1.4391g/cm3
Appearence

Etodolac appears as a fine, white to off-white crystalline powder. It is odourless and has a slight solubility in water, which makes it easily distinguishable from other chemical compounds by visual inspection.

Comment on solubility

Solubility of N',N'-diethyl-N-[2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethyl]ethane-1,2-diamine

The solubility of N',N'-diethyl-N-[2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethyl]ethane-1,2-diamine can be influenced by several factors, including its molecular structure and the presence of functional groups. Here are some key points regarding its solubility:

  • Polar vs. Non-Polar Regions: The presence of the ethane-1,2-diamine part, which has polar amine groups, suggests that the compound may have some affinity for polar solvents such as water.
  • Hydrophobic Behavior: The incorporation of a phenyl and pyrazole ring introduces hydrophobic characteristics, indicating that the compound might be less soluble in polar environments.
  • Solvent Interaction: It is likely that the compound will exhibit varying solubility in different solvents; for example, it may dissolve better in organic solvents compared to water.
  • Temperature and pH Dependence: Its solubility may also change based on temperature and pH, as some amines are known to form soluble complexes in acidic conditions.

Due to the complex nature of this compound's structure, it is advisable to conduct empirical tests to precisely determine its solubility profile in various solvents. As noted, “the solubility of a compound often reflects its chemical functionality and environmental interactions.” Thus, exploring its behavior in a laboratory setting will provide a clearer understanding of its solubility characteristics.

Interesting facts

Interesting Facts about N',N'-diethyl-N-[2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethyl]ethane-1,2-diamine

N',N'-diethyl-N-[2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethyl]ethane-1,2-diamine is a fascinating compound that has garnered attention for its unique structural features and potential applications. Here are some intriguing insights:

  • Complex Structure: This compound contains a pyrazole moiety, which is notable for its diverse pharmacological activities. Pyrazole derivatives are often explored in medicinal chemistry for their anti-inflammatory, analgesic, and antitumor properties.
  • Functional Groups: The presence of both ethyl and amino groups suggests that this compound has the potential for various intramolecular interactions, enhancing its reactivity and utility in complex organic synthesis.
  • Pharmacological Potential: Compounds featuring this type of structure are frequently assessed for their ability to inhibit enzymes or modulate biological pathways, making them candidates for drug development in areas such as cancer treatment or neuropharmacology.
  • Molecular Versatility: The incorporation of both hydrophilic (e.g., the diethylamine) and lipophilic (e.g., the aromatic and pyrazole segments) components opens up possibilities for designing molecules that can easily traverse biological membranes, which is critical in drug design.
  • Research Relevance: There is ongoing research into the mechanisms of action of pyrazole-based compounds, with studies indicating that they may play a role in metabolic regulation and cellular signaling.

In conclusion, N',N'-diethyl-N-[2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethyl]ethane-1,2-diamine exemplifies the intersection of structural complexity and potential therapeutic utility, making it a compound worthy of further investigation in various scientific fields.

Synonyms
P-317
BRN 0823064
15083-48-4
ETHYLENEDIAMINE, N,N-DIETHYL-N'-(2-(3-METHYL-1-PHENYL-5-PYRAZOLYLOXY)ETHYL)-
DTXSID10164622
N,N-Diethyl-N'-(2-(3-methyl-1-phenyl-5-pyrazolyloxy)ethyl)ethylenediamine
DTXCID4087113