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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
N',N'-diethyl-N-(4-methyl-3-phenyl-phenyl)hexane-1,6-diamine
State
State

Lidocaine is typically found in a solid state at room temperature as a powder, but it can also exist in solution when formulated for medical use.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
0.9940g/cm3
Appearence

Lidocaine is generally a white or slightly yellow crystalline powder. It is odorless and has a slightly bitter taste. In terms of solubility, it is freely soluble in water and in alcohol, and sparingly soluble in chloroform and in ether.

Comment on solubility

Solubility of N',N'-diethyl-N-(4-methyl-3-phenyl-phenyl)hexane-1,6-diamine

N',N'-diethyl-N-(4-methyl-3-phenyl-phenyl)hexane-1,6-diamine is an organic compound that exhibits interesting solubility characteristics. Due to its molecular structure, the solubility of this compound can be influenced by several factors:

  • Polarity: The presence of amine groups (-NH2) suggests that the compound may be polar, allowing it to dissolve in polar solvents such as water.
  • Hydrophobicity: The long hydrocarbon chains and the phenyl rings contribute to hydrophobic properties, making it more soluble in organic solvents like ethanol, chloroform, or acetone.
  • Hydrogen Bonding: The amine groups can participate in hydrogen bonding, which is favorable for solubility in polar environments, enhancing solubility in alcohols.
  • Temperature Effects: Generally, the solubility can increase with temperature, making it more soluble in warm solvents than in cold ones.

In conclusion, while N',N'-diethyl-N-(4-methyl-3-phenyl-phenyl)hexane-1,6-diamine may have limited solubility in water due to its hydrophobic regions, its capability to dissolve in various organic solvents is significantly enhanced. “Understanding the solubility behavior of compounds is critical for their applications in chemical synthesis and formulation.”

Interesting facts

Interesting Facts about N',N'-diethyl-N-(4-methyl-3-phenyl-phenyl)hexane-1,6-diamine

N',N'-diethyl-N-(4-methyl-3-phenyl-phenyl)hexane-1,6-diamine is a fascinating compound with diverse applications and characteristics that make it worth exploring. Here are some intriguing facts about this compound:

  • Functional Diversity: This compound is a member of the amine family, which is known for its role in organic chemistry. Amines are pivotal in creating a vast range of chemicals, including pharmaceuticals and agrochemicals.
  • Synthetic Importance: Due to its unique structure, which incorporates both aliphatic and aromatic components, it can serve as a crucial intermediate in the synthesis of more complex molecules.
  • Biological Relevance: Compounds with amine functionalities often exhibit biological activity. This particular compound might be investigated for potential applications in medicinal chemistry, where modifications can lead to improved efficacy or reduced toxicity.
  • Structure-Activity Relationship (SAR): The presence of a diethyl group and a phenyl ring contributes to how the molecule interacts with biological targets, offering popular avenues to explore in SAR studies.
  • Emphasis on Asymmetric Synthesis: The presence of multiple functional groups invites researchers to explore asymmetric synthesis techniques, which can yield compounds with distinct optical properties useful in chiral drug development.

In conclusion, N',N'-diethyl-N-(4-methyl-3-phenyl-phenyl)hexane-1,6-diamine is not just a compound with a complex name; it represents an intersection of synthetic chemistry, biological activity, and practical applications. Its unique makeup serves as a springboard for both fundamental research and industrial applications, underscoring the importance of exploring and understanding compounds like this.