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Dimebon

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Identification
Molecular formula
C21H28N2
CAS number
3613-73-8
IUPAC name
N,N-diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine
State
State

At room temperature, Dimebon is a solid.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.00
Boiling point (Celsius)
471.50
Boiling point (Kelvin)
744.65
General information
Molecular weight
310.46g/mol
Molar mass
310.4580g/mol
Density
1.0675g/cm3
Appearence

Dimebon typically appears as a solid crystalline powder. It is typically off-white to yellowish in color.

Comment on solubility

Solubility of N,N-diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine

The solubility characteristics of N,N-diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine (C21H28N2) are influenced by its unique structural features. This compound is comprised of a bulky indan moiety along with two ethyl groups and a phenyl group that can significantly affect its interaction with solvents.

In general, solubility can be analyzed through the following considerations:

  • Polarity: The presence of nitrogen atoms conjugated in the amine functional groups often enhances solubility in polar solvents. However, the overall non-polar characteristics introduced by the large hydrocarbon chains and rings may reduce solubility in water.
  • Solvent Type: N,N-diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine is likely to be more soluble in organic solvents such as ethanol or chloroform compared to aqueous environments.
  • Hydrophobic Effect: The hydrocarbon sections of the molecule increase hydrophobicity, making it less likely to dissolve in water; hence, it can precipitate out of aqueous solutions.

While exact solubility values can vary based on temperature and specific conditions, one can anticipate that N,N-diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine favors solubility in organic solvents more than in polar solvents. Therefore, for practical applications, it is advisable to utilize suitable organic solvents to ensure optimal solubility and reactivity.

Interesting facts

Exploring N,N-Diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine

N,N-Diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine is a fascinating compound that belongs to the family of diamines. This unique molecule is recognized for its multifaceted applications in both scientific research and industrial chemistry.

Key Features and Applications

  • Pharmaceutical Relevance: This compound has garnered attention for its potential use in drug development. The indan moiety may contribute to biological activity, making it an interesting candidate for further pharmacological studies.
  • Ligand Properties: N,N-Diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine can act as a ligand in coordination chemistry, opening avenues for the creation of novel coordination complexes that can have catalytic properties.
  • Research Utilization: It serves as a valuable intermediate in organic synthesis, helping chemists create more complex molecules through various chemical reactions.

Noteworthy Chemical Characteristics

This compound features a symmetrical structure due to its specific arrangement of amine groups and hydrocarbons, which influences its chemical reactivity and interaction with other substances. The presence of two ethyl groups adds to its steric bulk, affecting how it interacts in different environments.

Quote to ponder: "Chemistry is the art of transformation; compounds like N,N-Diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine exemplify the creative possibilities of molecular design."

Conclusion

As a bridge between biological systems and synthetic chemistry, N,N-Diethyl-N'-indan-2-yl-N'-phenyl-propane-1,3-diamine is a compound rich in potential and intrigue. With ongoing research, it is likely that future studies will reveal even more applications, solidifying its importance in the chemical sciences.

Synonyms
APRINDINE
Aprinidine
37640-71-4
Aprindin
Aprindina
Aprindinum [INN-Latin]
Aprindina [INN-Spanish]
Aprindinum
Fibocil
COMPOUND 99170
AC 1802
N,N-Diethyl-N'-2-indanyl-N'-phenyl-1,3-propanediamine
Aprindine [USAN:INN:BAN]
1,3-Propanediamine, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-
N-(3-(Diethylamino)propyl)-N-phenyl-2-indanamine
N'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N'-phenylpropane-1,3-diamine
N-(2,3-Dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-1,3-propanediamine
APRINDINE [INN]
APRINDINE [MI]
APRINDINE [USAN]
Compd 99170
Lilly 99170
5Y48085P9Q
APRINDINE [WHO-DD]
COMPOUND-99170
DTXSID3022615
AC-1802
Aprindinum (INN-Latin)
Aprinidine; Compd 99170; Lilly 99170
Aprindina (INN-Spanish)
{3-[(2,3-dihydro-1H-inden-2-yl)(phenyl)amino]propyl}diethylamine
N/'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N/'-phenylpropane-1,3-diamine
Aprindine (USAN/INN)
(3-((2,3-dihydro-1H-inden-2-yl)(phenyl)amino)propyl)diethylamine
UNII-5Y48085P9Q
SCHEMBL34545
DTXCID702615
CHEMBL1213033
CHEBI:135370
HY-A0236
N,3-propanediamine monohydrochloride
NSC284614
N-(2,3-Dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-1,3-propaned iamine
N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenylpropane-1,3-diamine
DB01429
SDCCGSBI-0633804.P001
NCGC00186042-01
N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)-2-(dimethylamino)propionamide,compound with 4-butyl-1,2-diphenylpyrazolidine-3,5-dione (1:1)
CS-0017583
NS00004164
D02969
Q263612
BRD-K53236343-003-03-7
1, N-(2,3-dihydro-1H-inden-2-yl)-N',N'-diethyl-N-phenyl-, monohydrochloride