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N,N-Diethylacetamide

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Identification
Molecular formula
C6H13NO
CAS number
685-91-6
IUPAC name
N,N-diethylacetamide
State
State

At room temperature, N,N-Diethylacetamide is in a liquid state.

Melting point (Celsius)
-63.00
Melting point (Kelvin)
210.15
Boiling point (Celsius)
185.00
Boiling point (Kelvin)
458.15
General information
Molecular weight
115.17g/mol
Molar mass
115.1730g/mol
Density
0.9224g/cm3
Appearence

N,N-Diethylacetamide is a colorless liquid with a faint amine-like odor.

Comment on solubility

Solubility of N,N-Diethylacetamide

N,N-Diethylacetamide, with the chemical formula C6H13N1O1, exhibits interesting solubility characteristics that are particularly relevant in various chemical processes. This compound is known for its compatibility with a range of solvents, which makes it valuable in many applications.

Key aspects of the solubility of N,N-Diethylacetamide include:

  • Polar Nature: Due to the presence of the carbonyl group (C=O), N,N-diethylacetamide exhibits polar characteristics that enhance its solubility in polar solvents.
  • Solvent Compatibility: It is soluble in water, ethanol, and ether, making it a versatile solvent in organic synthesis.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules contributes to its solubility, enabling better interaction in aqueous environments.

In conclusion, the solubility of N,N-Diethylacetamide can be summarized by its ability to dissolve in both polar and non-polar solvents, which broadens its application scope in various fields, including pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts about N,N-Diethylacetamide

N,N-Diethylacetamide is a fascinating compound in the realm of organic chemistry, particularly known for its unique properties and versatile applications. As a derivative of acetamide, it belongs to the category of amides and features an ethyl group positioned on both nitrogen atoms.

Key Applications

  • Synthetic Intermediary: It serves as a vital building block in the synthesis of various pharmaceuticals and agrochemicals.
  • Solvent: N,N-Diethylacetamide is often utilized as an effective solvent in organic reactions due to its ability to dissolve a range of organic compounds.
  • Reaction Medium: It can act as a reaction medium in numerous chemical processes, particularly in reactions that require a polar, aprotic solvent.

Noteworthy Properties

This compound has intriguing characteristics, making it attractive in various fields:

  • Polarity: The amide functional group imparts considerable polarity, enhancing its solvation capabilities.
  • Thermal Stability: N,N-Diethylacetamide demonstrates commendable stability under a range of temperature conditions.

Chemical Behavior

From a chemical perspective, N,N-diethylacetamide can participate in various reactions:

  • Amidation Reactions: It can readily undergo amidation, forming new amide bonds, which is crucial in synthesizing pharmaceuticals.
  • Hydrolysis: Under certain conditions, it can hydrolyze into acetic acid and diethylamine, showcasing its reactivity.

As a final note, it's essential to highlight the significance of safety precautions while handling N,N-diethylacetamide. Always ensure appropriate protective equipment is used to minimize any risks associated with its use in laboratory settings. Its essential role within organic chemistry underpins the importance of similar compounds in advancing scientific inquiry and developing new technologies.

Synonyms
N,N-DIETHYLACETAMIDE
Acetamide, N,N-diethyl-
N,N-Diaethylacetamid
N,N-Diaethylacetamid [German]
HSDB 5513
NSC 101
Acetic acid, amide, N,N-diethyl
EINECS 211-685-2
UNII-6YO81D7ST6
BRN 1209428
DTXSID9020459
AI3-02182
NSC-101
CH3CON(C2H5)2
DTXCID10459
4-04-00-00349 (Beilstein Handbook Reference)
N,N-DIETHYLACETAMIDE [HSDB]
N,NDiaethylacetamid
Acetamide, N,Ndiethyl
Acetic acid, amide, N,Ndiethyl
2,2-diethylacetamide
ajfdbnqqdylmjn-uhfffaoysa-n
diethylacetamide
inchi=1/c6h13no/c1-4-7(5-2)6(3)8/h4-5h2,1-3h
qvemwygblhqeak-uhfffaoysa-n
685-91-6
N,N-diethyl-acetamide
MFCD00009047
6YO81D7ST6
N-Acetyldiethylamine
Acetic acid diethylamide
n-diethylacetamide
N,N-diethylethanamide
N,N-di ethylacetamide
N.N-Diethyl acetamide
SCHEMBL18738
N,N-Diethylacetamide, 97%
NSC101
CHEMBL3184758
WLN: 2N2&V1
Tox21_200733
AKOS003862095
CS-W009545
DS-3397
NCGC00248816-01
NCGC00258287-01
CAS-685-91-6
SY037752
D0461
NS00036667
EN300-107551
H11276
Q27265731