Skip to main content

N,N-diethylformamide

ADVERTISEMENT
Identification
Molecular formula
C5H11NO
CAS number
617-84-5
IUPAC name
N,N-diethylformamide
State
State

At room temperature, N,N-diethylformamide is a liquid.

Melting point (Celsius)
-60.00
Melting point (Kelvin)
213.20
Boiling point (Celsius)
191.20
Boiling point (Kelvin)
464.30
General information
Molecular weight
101.16g/mol
Molar mass
101.1630g/mol
Density
0.9126g/cm3
Appearence

N,N-Diethylformamide is a colorless liquid. It is typically clear and has a characteristic amine-like odor.

Comment on solubility

Solubility of N,N-Diethylformamide

N,N-Diethylformamide (N,N-C2H5H2O) is a versatile solvent with notable solubility characteristics. Here are some key points regarding its solubility:

  • Solubility in Water: N,N-Diethylformamide is moderately soluble in water, largely due to its polar nature. This allows it to interact with water molecules, enabling a degree of solvation.
  • Solubility in Organic Solvents: It exhibits excellent solubility in many organic solvents such as alcohols, ethers, and carbon tetrachloride, making it a favorable medium for various chemical reactions and processes.
  • Concentration Effects: The solubility of N,N-Diethylformamide can be influenced by concentration levels; as concentration increases, the solvent's ability to dissolve other compounds also improves.
  • Temperature Influence: Increasing temperature generally enhances the solubility of N,N-Diethylformamide in both water and organic solvents, leading to greater molecular mobility and interaction.

In summary, N,N-Diethylformamide is a polar aprotic solvent with moderate water solubility and high compatibility with organic solvents, making it a valuable compound in numerous chemical applications. Its unique solubility profile showcases its flexibility as a solvent.

Interesting facts

Interesting Facts About N,N-Diethylformamide

N,N-diethylformamide (commonly abbreviated as DEFM) is an intriguing compound widely used in organic synthesis and as a solvent in various chemical processes. Here are some interesting points regarding this unique amide:

  • Versatile Solvent: DEFM is known for its excellent ability to dissolve a wide range of polar and non-polar compounds, making it invaluable in laboratories for various reactions, particularly those involving complex organic substrates.
  • Reactivity: This compound exhibits reactivity due to the presence of both an amine and a carbonyl group. It can participate in various chemical reactions, including nucleophilic substitutions and acylations.
  • Industrial Applications: N,N-diethylformamide is utilized in the production of pharmaceuticals, agrochemicals, and polymers, showcasing its importance beyond academic research.
  • Research Interest: Scientists are continuously exploring the potential of DEFM in catalysis and reaction mechanisms, as its behavior can sometimes yield unexpected results during chemical reactions.
  • Safety Considerations: It is crucial to handle DEFM with proper safety protocols, as exposure may lead to irritation and other health hazards. As with any chemical, understanding its properties is key to ensuring a safe laboratory environment.

In summary, N,N-diethylformamide stands out in the realm of organic chemistry, not just for its chemical structure but also for its broad applicability and role in advancing scientific research. As researchers continue to uncover its capabilities, DEFM remains a compound of significant interest in both academic and industrial settings.

Synonyms
N,N-DIETHYLFORMAMIDE
Diethylformamide
Formamide, N,N-diethyl-
Diethyl formamide
Diethylamid kyseliny mravenci
D4BLP8BN9H
NSC 6242
EINECS 210-533-2
Diethylamid kyseliny mravenci [Czech]
formamide, diethyl-
BRN 1209392
DTXSID3020463
AI3-11534
NSC-6242
DTXCID50463
NFormyldiethylamine
Formamide, N,Ndiethyl
4-04-00-00346 (beilstein handbook reference)
inchi=1/c5h11no/c1-3-6(4-2)5-7/h5h,3-4h2,1-2h
suakhgwarzswih-uhfffaoysa-n
617-84-5
N-Formyldiethylamine
Formyldiethylamine
N,N-diethyl-formamide
MFCD00003287
diethyl-formamide
N,N-diethylormamide
n.n-diethylformamide
Formamide,N-diethyl-
N,N-diethyl formamide
UNII-D4BLP8BN9H
SCHEMBL27084
N,N-Diethylformamide, 99%
WLN: VHN2&2
CHEMBL3186600
NSC6242
CHEBI:183296
Tox21_200919
AKOS009156839
CS-W009551
NCGC00248876-01
NCGC00258473-01
AS-17885
CAS-617-84-5
DB-053987
D0506
D4234
NS00019831
EN300-91618
A10832
Q4044797