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N,N-diethylpiperidine-3-carboxamide

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Identification
Molecular formula
C10H20N2O
CAS number
2281-14-3
IUPAC name
N,N-diethylpiperidine-3-carboxamide
State
State

At room temperature, N,N-diethylpiperidine-3-carboxamide is in a liquid state.

Melting point (Celsius)
-31.00
Melting point (Kelvin)
242.15
Boiling point (Celsius)
253.00
Boiling point (Kelvin)
526.15
General information
Molecular weight
184.29g/mol
Molar mass
184.2940g/mol
Density
0.9824g/cm3
Appearence

N,N-diethylpiperidine-3-carboxamide typically appears as a colorless to pale yellow liquid. It may have a mild odor, characteristic of amides.

Comment on solubility

Solubility of N,N-Diethylpiperidine-3-carboxamide

N,N-Diethylpiperidine-3-carboxamide, often referred to as DEPCA, exhibits an interesting solubility profile that is influenced by its molecular structure. This compound is characterized by the presence of both a nitrogen atom and an amide functional group, which play crucial roles in its solubility in various solvents. Generally, the solubility of DEPCA can be summarized as follows:

  • Polar Solvents: This compound shows good solubility in polar solvents such as water, methanol, and ethanol. The amide group can engage in hydrogen bonding with these solvents, facilitating dissolution.
  • Non-Polar Solvents: In contrast, DEPCA has limited solubility in non-polar solvents like hexane or toluene. The lack of polar interactions in these environments hinders the dissolving process.
  • Temperature Dependence: Solubility may also vary with temperature, with higher temperatures generally enhancing the solubility of organic compounds.

As stated, “like dissolves like,” meaning the solubility behavior of N,N-Diethylpiperidine-3-carboxamide aligns well with this principle. The balance of its polar and non-polar characteristics dictates its compatibility with different solvent types, making it essential to consider the solvent's nature when preparing solutions.

In conclusion, understanding the solubility of DEPCA not only aids in practical applications but also deepens our insight into the interactions at the molecular level, shedding light on how the structural features of compounds dictate their behavior in various chemical environments.

Interesting facts

Interesting Facts about N,N-Diethylpiperidine-3-carboxamide

N,N-Diethylpiperidine-3-carboxamide, often referred to as a piperidine derivative, is an intriguing compound that has found diverse applications in various fields such as medicinal chemistry and organic synthesis. Here are some notable points about this compound:

  • Structural Significance: The compound features a piperidine ring, which is a six-membered ring containing one nitrogen atom. This aromatic structure significantly contributes to its biological activities.
  • Pharmacological Properties: Research indicates that analogs of N,N-diethylpiperidine-3-carboxamide exhibit various pharmacological properties, including potential use as analgesics and anti-inflammatory agents.
  • Synthetic Versatility: Due to its adaptable structure, this compound can serve as a building block in the synthesis of more complex molecules, making it valuable in drug development and chemical research.
  • Potential Research Applications: As scientists explore the properties of this compound, it may lead to the discovery of new therapeutic agents for treating chronic pain and other conditions.

In the words of chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This captures the spirit of ongoing research around compounds like N,N-diethylpiperidine-3-carboxamide, where every new finding can lead to significant advancements in pharmacology and medicinal chemistry.

Overall, N,N-diethylpiperidine-3-carboxamide represents the fascinating intersection of synthetic chemistry and pharmacology, continually inviting scientists to explore its potential.

Synonyms
N,N-Diethylpiperidine-3-carboxamide
N,N-Diethyl-3-piperidinecarboxamide
DTXSID40955287
DTXCID701383288
222-136-1
N,N-Diethylnipecotamide
3367-95-1
3-Piperidinecarboxamide, N,N-diethyl-
NIPECOTAMIDE, N,N-DIETHYL-
3-(N,N-Diethylcarbamoyl)piperidine
piperidine-3-carboxylic acid diethylamide
EINECS 222-136-1
BRN 0005401
AI3-36608
N,N-Diethylnipecotamide (tech.)
Diethylnipecotamide
N,N-Diethylnipeotamide
HUA6N8KRA7
SCHEMBL441660
3-(Diethylcarbamoyl)piperidine
N,N-Diethylnipecotamide, 98%
3-(Diethylcarboxamido)piperidine
ALBB-030084
3-[(Diethylamino)carbonyl]piperidine
GEO-01047
MFCD00005990
AKOS000165905
AKOS017343298
CS-W000355
N,N-Diethyl-3-piperidinecarboxamide #
SB41096
Piperidin-3-carboxylic acid diethylamide
NS00049808
EN300-59207
D77620