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5-Nitro-DMT

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Identification
Molecular formula
C11H13N3O2
CAS number
1626-01-7
IUPAC name
N,N-dimethyl-1-(5-nitro-1H-indol-3-yl)methanamine
State
State

At room temperature, 5-Nitro-DMT is a solid. Its crystalline form is stable under standard environmental conditions.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
495.35
Boiling point (Kelvin)
768.50
General information
Molecular weight
233.25g/mol
Molar mass
233.2520g/mol
Density
1.4120g/cm3
Appearence

5-Nitro-DMT typically appears as a crystalline solid. The compound's visual characteristics can vary depending on its state of purity, and may exhibit a range of shades from beige to yellowish. The crystals are often small and may appear as powdery or granular chunks.

Comment on solubility

Solubility of N,N-dimethyl-1-(5-nitro-1H-indol-3-yl)methanamine

N,N-dimethyl-1-(5-nitro-1H-indol-3-yl)methanamine is a compound that presents interesting solubility characteristics. Generally, the solubility of such organic compounds can be influenced by various factors, including:

  • Polarity: The presence of functional groups can increase polarity, affecting its interaction with solvents.
  • Hydrogen bonding: The ability to form hydrogen bonds can enhance solubility in polar solvents.
  • Hydrophobic interactions: Non-polar parts of the molecule might reduce solubility in water but increase it in organic solvents.

In particular, N,N-dimethyl-1-(5-nitro-1H-indol-3-yl)methanamine tends to be sparingly soluble in water due to the presence of a hydrophobic indole structure. However, it shows greater solubility in organic solvents, such as:

  • Dimethyl sulfoxide (DMSO)
  • Ethanol
  • Acetone

This behavior showcases a common trend in many nitro-substituted compounds, where strong polar interactions with the solvent can enhance solvation. Nevertheless, it is essential to consider that solubility can also vary with temperature and pH, meaning that optimal conditions must be determined experimentally.

Understanding the solubility characteristics of this compound is crucial for its applications in various fields, including pharmaceuticals and material sciences, where solvent compatibility plays a significant role.

Interesting facts

Exploring N,N-Dimethyl-1-(5-nitro-1H-indol-3-yl)methanamine

N,N-Dimethyl-1-(5-nitro-1H-indol-3-yl)methanamine is a fascinating compound that bridges the fields of medicinal chemistry and biological research. Known for its role in various studies, this compound holds potential in the realm of therapeutic applications.

Interesting Characteristics:

  • Complex Structure: Its unique structure incorporates both a nitro group and an indole moiety, which are often found in naturally occurring compounds and pharmaceuticals.
  • Biological Relevance: Compounds like this one are frequently investigated for their activity in biological systems, especially in relation to cancer research and neurobiology.
  • Chemical Versatility: The presence of the dimethylamino functional group provides important *nucleophilic* properties, which can facilitate various chemical reactions.
  • Research Applications: It is commonly used as a building block in the synthesis of more complex molecules or as a probe in scientific studies aimed at understanding biological pathways.

Quote from the field: "The nitroindole framework has provided chemists with numerous unique derivatives that exhibit significant biological activities." This statement highlights the importance of the indole structure in medicinal chemistry.

Future research is likely to shed more light on the compound's mechanisms and possible applications, further establishing its significance in science and medicine. As *scientific inquiry* continues, compounds like N,N-dimethyl-1-(5-nitro-1H-indol-3-yl)methanamine remain at the forefront, tantalizing researchers with their potential.

Synonyms
5-Nitrogramine
3414-64-0
N,N-dimethyl-1-(5-nitro-1H-indol-3-yl)methanamine
INDOLE, 3-((DIMETHYLAMINO)METHYL)-5-NITRO-
N,N-dimethyl-5-nitro-1H-indole-3-methanamine
MFCD00544197
MLS002667850
dimethyl[(5-nitro-1H-indol-3-yl)methyl]amine
Indole, 3-[(dimethylamino)methyl]-5-nitro-
1H-Indole-3-methanamine, N,N-dimethyl-5-nitro-
NSC 56889
BRN 0216692
3-((Dimethylamino)methyl)-5-nitroindole
NSC56889
Oprea1_367827
CBDivE_000986
CBDivE_002690
4-22-00-04317 (Beilstein Handbook Reference)
SCHEMBL8538163
CHEMBL1881648
DTXSID10187730
SVNVKGIWGOHXPW-UHFFFAOYSA-N
HMS3089M21
NSC-56889
AKOS005259116
AC-27830
BS-25238
SMR001557607
SY248340
CS-0451345
1H-Indole-3-methanamine,N-dimethyl-5-nitro-
3-(DIMETHYLAMINOMETHYL)-5-NITROINDOLE
3-[(dimethylamino)methyl]-5-nitro-1H-indole
A822097
AH-262/34642020
SR-01000196476
SR-01000196476-1