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Gramine

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Identification
Molecular formula
C11H14N2
CAS number
87-52-5
IUPAC name
N,N-dimethyl-1-(7-methyl-1H-indol-3-yl)methanamine
State
State

At room temperature, Gramine is typically a solid.

Melting point (Celsius)
137.00
Melting point (Kelvin)
410.15
Boiling point (Celsius)
309.00
Boiling point (Kelvin)
582.15
General information
Molecular weight
174.25g/mol
Molar mass
174.2580g/mol
Density
1.1045g/cm3
Appearence

Gramine appears as a white solid. It is typically found in crystalline form but can appear as a powder as well. The solid is odorless or possesses a slightly amine-like odor.

Comment on solubility

Solubility of N,N-dimethyl-1-(7-methyl-1H-indol-3-yl)methanamine

N,N-dimethyl-1-(7-methyl-1H-indol-3-yl)methanamine is an intriguing compound with unique solubility characteristics. Understanding its solubility is crucial for various applications in chemical research and industry. Here are some key points regarding its solubility:

  • Polarity: The compound contains both hydrophobic indole and more polar amine groups, which can influence its solubility in different solvents.
  • Solvent Interaction: It is likely to be soluble in organic solvents such as ethanol and methanol due to its non-polar regions, while exhibiting limited solubility in water.
  • Temperature Dependence: Generally, the solubility of such compounds can increase with temperature, leading to enhanced dissolution rates.
  • pH Variability: The solubility can also be affected by the pH of the solution; at varying pH levels, the ionization of the amine group may improve solubility in certain environments.

In summary, while N,N-dimethyl-1-(7-methyl-1H-indol-3-yl)methanamine demonstrates a preference for non-polar solvents, its solubility may vary significantly depending on temperature and pH. Understanding these relationships is essential for maximizing its usefulness in practical applications.

Interesting facts

Interesting Facts about N,N-dimethyl-1-(7-methyl-1H-indol-3-yl)methanamine

N,N-dimethyl-1-(7-methyl-1H-indol-3-yl)methanamine, often referred to in scientific circles as a complex organic compound, has intrigued researchers due to its unique structure and potential applications. Here are some fascinating points regarding this compound:

  • Structural Uniqueness: The presence of a 7-methyl-1H-indole moiety contributes to its structural complexity, making it a subject of interest in organic chemistry and drug design.
  • Biological Significance: It is often studied in the context of neurotransmitter systems, particularly due to potential interactions with serotonin receptors, and helps in understanding various neurological functions.
  • Research Applications: The compound is being explored for its potential as a pharmaceutical agent, especially in treating conditions related to mood and cognitive disorders.
  • Synthesis Challenges: The synthesis of this compound presents unique challenges due to its complex structure; however, innovative synthetic techniques are continuously being developed to enhance efficiency.
  • Interdisciplinary Studies: Its study integrates areas such as medicinal chemistry, pharmacology, and materials science, showcasing the multifaceted nature of modern chemical research.

The exploration of N,N-dimethyl-1-(7-methyl-1H-indol-3-yl)methanamine exemplifies how organic compounds can offer significant insights into medicinal applications while challenging chemists with their intricate architectures. As research advances, this compound remains at the forefront of studies aimed at discovering effective therapeutic agents.

Synonyms
7-Methylgramine
13712-78-2
N,N-dimethyl-1-(7-methyl-1H-indol-3-yl)methanamine
1H-Indole-3-methanamine, N,N,7-trimethyl-
MFCD00049078
INDOLE, 3-((DIMETHYLAMINO)METHYL)-7-METHYL-
dimethyl[(7-methyl-1H-indol-3-yl)methyl]amine
BRN 0128429
3-(Dimethylaminomethyl)-7-methylindole
SCHEMBL11494193
SCHEMBL31415131
DTXSID70160084
AKOS005259023
FM52356
BS-20811
DB-042376
CS-0210298
G84576