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N,N-Dimethyl-1H-benzimidazol-2-amine

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Identification
Molecular formula
C9H11N3
CAS number
1146-19-4
IUPAC name
N,N-dimethyl-1H-benzimidazol-2-amine
State
State

At room temperature, N,N-Dimethyl-1H-benzimidazol-2-amine is in a solid state. The compound's stability and relatively high melting point make it conducive to maintaining this physical state under typical environmental conditions.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
322.00
Boiling point (Kelvin)
595.15
General information
Molecular weight
175.23g/mol
Molar mass
175.2320g/mol
Density
1.2050g/cm3
Appearence

The compound typically appears as a crystalline solid that can range from colorless to pale yellow in color. It is a stable compound under normal conditions and may exhibit a slight amine-like odor due to its dimethylamino group.

Comment on solubility

Solubility of N,N-dimethyl-1H-benzimidazol-2-amine

N,N-dimethyl-1H-benzimidazol-2-amine, a compound with a complex structure, exhibits interesting solubility properties that are worth discussing.

  • Solvent Dependence: The solubility of this compound can vary significantly depending on the solvent used. Generally, it is more soluble in polar solvents compared to non-polar solvents.
  • Water Solubility: It is moderately soluble in water, which can be attributed to the presence of nitrogen atoms that can engage in hydrogen bonding with water molecules.
  • Organic Solvents: In organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO), the solubility tends to increase, making these solvents preferable for reactions and extractions involving this compound.

As with many organic compounds, factors such as temperature and concentration can also influence solubility. For example, increased temperature often leads to enhanced solubility due to increased molecular motion, allowing for more interaction with the solvent molecules.

In summary, the solubility of N,N-dimethyl-1H-benzimidazol-2-amine is characterized by:

  • Moderate solubility in water
  • Higher solubility in polar organic solvents
  • Temperature-dependent variations

Understanding the solubility of this compound is crucial for its practical applications in various fields, from pharmaceuticals to chemical synthesis.

Interesting facts

Interesting Facts about N,N-dimethyl-1H-benzimidazol-2-amine

N,N-dimethyl-1H-benzimidazol-2-amine is a fascinating compound with a variety of applications and properties. This organic molecule belongs to the class of benzimidazoles, known for their versatility in medicinal chemistry. Here are a few key points that highlight its significance:

  • Medicinal Uses: Compounds like N,N-dimethyl-1H-benzimidazol-2-amine are often investigated for their therapeutic potential. They have shown promise as:
    • Antimicrobial agents
    • Anti-cancer drugs
    • Anti-inflammatory compounds
  • Synthetic Pathways: The synthesis of N,N-dimethyl-1H-benzimidazol-2-amine usually involves:
    • Condensation reactions
    • Methylation processes
    • Multistep synthetic routes for complex derivatives
  • Biological Activity: Studies on benzimidazole derivatives have indicated a variety of biological activities, including:
    • Antiviral properties, offering a potential for treating viral infections
    • Interaction with various enzyme systems
    • Impact on cell signaling pathways, making them crucial in cancer research
  • Environmental Impact: As organic compounds, benzimidazoles like N,N-dimethyl-1H-benzimidazol-2-amine require careful consideration for their environmental impact, particularly in:
    • Agricultural applications, such as fungicides
    • Potential bioaccumulation in ecosystems
    • Regulatory compliance for safety and sustainability

In summary, N,N-dimethyl-1H-benzimidazol-2-amine is not just an interesting chemical entity; it is a bridge between theoretical chemistry and practical applications in medicine, agriculture, and beyond. As research continues, this compound might uncover even more hidden potentials!

Synonyms
2851-13-0
N,N-dimethyl-1H-benzo[d]imidazol-2-amine
1H-Benzimidazol-2-amine, N,N-dimethyl-
N,N-dimethyl-1H-benzimidazol-2-amine
BENZIMIDAZOLE, 2-DIMETHYLAMINO-
2-Dimethylaminobenzimidazole
N,N-DIMETHYL-1H-BENZOIMIDAZOL-2-AMINE
BRN 0124090
MFCD01231011
dimethylaminobenzimidazole
5-25-10-00412 (Beilstein Handbook Reference)
SCHEMBL358399
DTXSID20182731
NMTCCVZABWWGSB-UHFFFAOYSA-N
XH0048
AKOS022871335
DS-19357
DB-265968
N,N-dimethyl-1H-benzo[d]imidazole-2-amine
CS-0160407
A10867
N,N-DIMETHYL-1H-1,3-BENZODIAZOL-2-AMINE
InChI=1/C9H11N3/c1-12(2)9-10-7-5-3-4-6-8(7)11-9/h3-6H,1-2H3,(H,10,11