Skip to main content

Orphenadrine

ADVERTISEMENT
Identification
Molecular formula
C18H23NO
CAS number
83-98-7
IUPAC name
N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine
State
State

At room temperature, Orphenadrine is primarily in a solid state.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
366.10
Boiling point (Kelvin)
639.25
General information
Molecular weight
265.38g/mol
Molar mass
265.3760g/mol
Density
0.9481g/cm3
Appearence

Orphenadrine typically appears as a white crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine

N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine, with the chemical formula C18H23NO, is a compound whose solubility can be influenced by a variety of factors. Understanding its solubility characteristics is essential for applications in both laboratory and pharmacological settings.

Factors Affecting Solubility

Several factors can impact the solubility of this compound:

  • Polarity: The presence of polar functional groups, such as the amine (–NH) and ether (–O–) components, can enhance solubility in polar solvents like water or alcohols.
  • Hydrophobic Regions: The phenyl and pyridyl groups in the compound contribute to hydrophobic interactions, potentially limiting solubility in water, but enhancing it in organic solvents.
  • Temperature: Increasing temperature generally increases solubility for most solid compounds; however, specific behaviors can vary based on the compound structure.

Expected Solubility Behavior

While specific quantitative solubility data may not be readily available, it is likely that:

  • The compound may exhibit moderate solubility in organic solvents (e.g., ethanol, dichloromethane).
  • Its solubility in water is anticipated to be limited due to its relatively large hydrophobic character.
  • Using cosolvents or adjusting pH could potentially enhance its solubility profile.

In conclusion, the solubility of N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine is dictated by a complex interplay of molecular interactions. Therefore, practical experiments are essential for obtaining accurate solubility assessments in various solvents.

Interesting facts

Interesting Facts about N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine

N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine, often referred to as a complex organic compound, holds a fascinating position in the world of medicinal chemistry. Here are some intriguing insights:

  • Pharmacological Potential: This compound is studied for its interactions with various biological targets, offering insight into potential therapeutic applications. Research suggests that it may possess pharmacological activities, including anti-tumor properties.
  • Structurally Unique: The presence of both a phenyl and a pyridyl group contributes to the compound's unique structure. These aromatic systems can enhance its lipophilicity, potentially affecting how it interacts with biological membranes.
  • Research and Development: Compounds like this one often serve as lead compounds in drug discovery. Scientists utilize their structures to modify and create derivatives, leading to compounds with improved efficacy or reduced side effects. Innovation in this field is critical for developing new treatments.
  • Applications in Neuroscience: Compounds with similar structures have been investigated for their effects on neurotransmitter systems, particularly in relation to diseases affecting mental health. This compound’s unique properties could make it valuable in understanding conditions like depression or anxiety.

As research continues, N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine could pave the way for new discoveries in how we approach treatment for various conditions. With its distinctive structure and promising biological activity, the future of this compound is both bright and full of potential.

Synonyms
doxylamine
469-21-6
Dossilamina
Doxylaminum
Doxilminio
doxilamina
(+/-)-Doxylamine
Doxylaminum [INN-Latin]
Doxilminio [INN-Spanish]
N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine
R-Doxylamine
2-Dimethylaminoethoxyphenylmethyl-2-picoline
NCI C60684
N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine
Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether
HSDB 5184
UNII-95QB77JKPL
2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine
EINECS 207-414-2
95QB77JKPL
Doxylamine (INN)
BRN 0230379
Ethanamine, N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-
Doxylaminephenyl-d5
CHEBI:51380
dimethyl({2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethyl})amine
S-Doxylamine
DTXSID1022970
Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-
Dossilamina [DCIT]
EC 207-414-2
Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-
5-21-03-00508 (Beilstein Handbook Reference)
Decapryn (TN)
DOXYLAMINE [INN]
Doxylaminum (INN-Latin)
Doxilminio (INN-Spanish)
Doxylamine [INN:BAN]
N,N-dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine
Pyridine, 2-[.alpha.-[2-(dimethylamino)ethoxy]-.alpha.-methylbenzyl]-
N,N-dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethanamine
()-Doxylamine
PYRIDINE, 2-(.ALPHA.-(2-(DIMETHYLAMINO)ETHOXY)-.ALPHA.-METHYLBENZYL)-
N,N-Dimethyl-2-[(1S)-1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine; (S)-N,N-Dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethanamine
N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine; 2-[alpha-[2-(Dimethylamino)ethoxy]-alpha-methylbenzyl]pyridine; Doxylamine; LS 127;
Spectrum_001014
DOXYLAMINE [MI]
Prestwick0_000027
Prestwick1_000027
Prestwick2_000027
Prestwick3_000027
Spectrum2_000115
Spectrum3_000409
Spectrum4_000528
Spectrum5_000949
DOXYLAMINE [HSDB]
DOXYLAMINE [VANDF]
N,N-DIMETHYL-2-
SCHEMBL4709
CHEMBL1004
DOXYLAMINE [WHO-DD]
Lopac0_000348
BSPBio_000093
BSPBio_001938
KBioGR_001135
KBioSS_001494
DivK1c_000841
SPBio_000130
SPBio_002014
BPBio1_000103
DTXCID102970
GTPL7171
KBio1_000841
KBio2_001494
KBio2_004062
KBio2_006630
KBio3_001158
R06AA09
NINDS_000841
HMS3604L05
BCP09058
N,N-dimethyl-2-[(1-phenyl-1-pyridin-2-ylethyl)oxy]ethanamine
RFC84933
STL018676
AKOS005657227
CCG-204443
DB00366
SDCCGSBI-0050336.P005
IDI1_000841
NCGC00021147-02
NCGC00021147-03
NCGC00021147-04
NCGC00021147-05
NCGC00021147-06
NCGC00021147-08
NCGC00021147-09
NCGC00021147-13
NCGC00021147-21
NCGC00089789-02
NCGC00089789-04
NCGC00089789-05
AC-15949
SBI-0050336.P004
DB-051407
AB00053466
NS00000474
D07878
EN300-123421
AB00053466-18
AB00053466_19
AB00053466_20
.alpha.-Dimethylaminoethoxyphenylmethyl-2-picoline
L001076
Q423390
2-DIMETHYLAMINOETHOXYPHENYL-METHYL-2-PICOLINE
BRD-A44008656-036-05-0
BRD-A44008656-036-15-9
BRD-A44008656-036-24-1
BRD-A44008656-036-25-8
Z2242151271
Phenyl-2-pyridylmethyl-.beta.-N,N-dimethylaminoethyl ether
N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine #
2-(.alpha.-(2-(Dimethylamino)ethoxy)-.alpha.-methylbenzyl)pyridine
2-(alpha(2-(DIMETHYLAMINO)ETHOXY)-alpha-METHYLBENZYL)PYRIDINE
2-(.ALPHA.(2-(DIMETHYLAMINO)ETHOXY)-.ALPHA.-METHYLBENZYL)PYRIDINE
2-(ALPHA-(2-DIMETHYLAMINOETHOXY)-ALPHA-METHYLBENZYL) PYRIDINE
207-414-2