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Desvenlafaxine succinate

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Identification
Molecular formula
C16H25NO2
CAS number
386750-22-7
IUPAC name
N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine;succinic acid
State
State

Desvenlafaxine succinate is in a solid state at room temperature.

Melting point (Celsius)
138.00
Melting point (Kelvin)
411.15
Boiling point (Celsius)
468.10
Boiling point (Kelvin)
741.30
General information
Molecular weight
399.48g/mol
Molar mass
263.3790g/mol
Density
1.2108g/cm3
Appearence

Desvenlafaxine succinate typically appears as a white to off-white crystalline powder. This appearance is common in many pharmaceutical compounds ensuring easy identification and handling.

Comment on solubility

Solubility of N,N-Dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine; Succinic Acid

The solubility of N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine in various solvents is influenced by its molecular structure and functional groups. When paired with succinic acid, the solubility characteristics can change significantly.

Factors Affecting Solubility

  • Polarity: The presence of polar functional groups tends to increase solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents can enhance solubility, particularly in aqueous environments.
  • Molecular Size: Larger molecules may have lower solubility due to steric hindrance and limited interaction with solvent molecules.

Typically, compounds like N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine may exhibit increased solubility in organic solvents, while its interaction with succinic acid could promote a better solubility profile in more polar solvents due to the formation of ion pairs.

General Solubility Insights

As a general rule of thumb, the following applies:

  1. Hydrophobic compounds: are less soluble in water.
  2. Hydrophilic compounds: display higher affinity to dissolve in polar solvents.
  3. Salts: often have enhanced solubility in water due to ionic interactions.

In conclusion, the solubility of N,N-dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine in the presence of succinic acid provides a fascinating area for study, owing to the balance of various forces at play.

Interesting facts

Interesting Facts About N,N-Dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine; Succinic Acid

N,N-Dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine, often referred to as a novel chemical entity, is a compound of great interest due to its potential applications in medicinal chemistry and pharmacology. When paired with succinic acid, a versatile dicarboxylic acid commonly found in various metabolic pathways, the combination creates a compound with unique characteristics.

Key Highlights:

  • Dual Functionality: This compound exhibits both amine and ether functionalities, enhancing its reactivity and interaction with biological systems.
  • Biological Potential: Compounds of this nature have been studied for their potential in drug development, especially in modulating neurological pathways.
  • Succinic Acid Role: Succinic acid plays a crucial role in the TCA (Krebs) cycle, making it an essential component in energy production in cells.
  • Research Applications: Scientists are exploring its application as a pharmacological agent, which could lead to the development of treatments for various psychiatric disorders.

In recent years, there has been increasing interest in compounds containing pyridine rings due to their stability and unique electron-accepting properties. The incorporation of phenyl groups enhances hydrophobic interactions, further increasing the likelihood of creating effective drug candidates. As research continues to unfold, the multifunctionality of this compound could lead to exciting developments in therapeutic strategies.

In conclusion, the combination of N,N-Dimethyl-2-[1-phenyl-1-(2-pyridyl)ethoxy]ethanamine with succinic acid exemplifies the fascinating interplay between different chemical moieties, opening doors for innovation in the field of pharmaceuticals.

Synonyms
Doxylamine succinate
Decapryn
Gittalun
Unisom
Hoggar N
Doxy-sleep-aid
Evigoa D
Decapryn Succinate
Alsadorm
Mereprine
Sedaplus
Doxylamine succinate (1:1)
Alsodorm
Donormyl
Dormidina
Meraprina
Decapryn succinate (1:1)
Topcare sleep aid
CCRIS 4811
EQUALINE SLEEP AID
Doxylamine succinate liquid
UNII-V9BI9B5YI2
EINECS 209-228-7
V9BI9B5YI2
NSC 74772
NSC-74772
DECAMIUM
DTXSID7020552
AI3-23993
2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate (1:1)
Doxylamine succinate (USP)
Doxylamine succinate [USP]
2-Dimethylaminoethoxyphenylmethyl-2-picoline succinate
DTXCID10552
Phenyl2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether succinate
NSC74772
alpha-(2-Dimethylaminoethoxy)-alpha-methyl-alpha-phenyl-2-picoline acid succinate
Ethanamine, N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-, butanedioate (1:1)
BONJESTA COMPONENT DOXYLAMINE SUCCINATE
DICLEGIS COMPONENT DOXYLAMINE SUCCINATE
BENDECTIN COMPONENT DOXYLAMINE SUCCINATE
DICLECTIN COMPONENT DOXYLAMINE SUCCINATE
DOXYLAMINE SUCCINATE (IARC)
DOXYLAMINE SUCCINATE [IARC]
DOXYLAMINE SUCCINATE (MART.)
DOXYLAMINE SUCCINATE [MART.]
DOXYLAMINE SUCCINATE (USP-RS)
DOXYLAMINE SUCCINATE [USP-RS]
DOXYLAMINE SUCCINATE (USP MONOGRAPH)
DOXYLAMINE SUCCINATE [USP MONOGRAPH]
DOXYLAMINE HYDROGEN SUCCINATE (EP IMPURITY)
DOXYLAMINE HYDROGEN SUCCINATE [EP IMPURITY]
DOXYLAMINE HYDROGEN SUCCINATE (EP MONOGRAPH)
DOXYLAMINE HYDROGEN SUCCINATE [EP MONOGRAPH]
Sambrosanight
Sambrosa
sleep aid ultra
Unisom Sleeptabs
Nocto Sleep Aid
Vicks ZzzQuilUltra
Basic Care Sleep Aid
SLEEP AID25mg
WAL SOM
Harris Teeter Sleep Aid
good sense sleep aid ultra
WAL SOMNIGHTTIME SLEEP AID
A-H-Tablets 100 mg, A-H-Tablets 25 mg
DOXYLAMINE SUCCINATE COMPONENT OF BONJESTA
DOXYLAMINE SUCCINATE COMPONENT OF DICLEGIS
DOXYLAMINE SUCCINATE COMPONENT OF BENDECTIN
DIMETHYLAMINOETHOXYMETHYLBENZYLPYRIDINE SUCCINATE
PHENYL 2-PYRIDYLMETHYL-BETA-N,N-DIMETHYLAMINOETHYL ETHER SUCCINATE
N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy) ethanamine, butanedioate(1:1)
209-228-7
Butanedioic Acid, compound with N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine(1:1)
562-10-7
Doxylamine (succinate)
Doxylamine hydrogen succinate
Doxylamine succinate salt
A-H Injection
Donormil
MFCD00056168
butanedioic acid;N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine
MLS000028417
CHEBI:82461
Doxylamine.succinate
SMR000058436
Decapryn (TN)
2-(alpha(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine succinate (1:1)
N,N-dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethanamine succinate
N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine succinate
SR-01000003036
Safetussin
2-[alpha[2-(Dimethylamino)ethoxy]-alpha-methylbenzyl]pyridine succinate (1:1)
NCGC00017028-02
CAS-562-10-7
Prestwick_887
Dimethylaminoethoxy-methyl-benzyl-pyridine succinate
Opera_ID_566
2-(alpha-(2-Dimethylaminoethoxy)-alpha-methylbenzyl)pyridine succinate
Pyridine, succinate (1:1)
MLS000758288
MLS001076141
MLS001424137
MLS002222274
SCHEMBL160443
SPECTRUM1500267
CHEMBL1200392
Doxylamine for system suitability
HMS502K03
DOXYLAMINE SUCCINATE [MI]
KBAUFVUYFNWQFM-UHFFFAOYSA-N
HMS1568E15
HMS1920K04
HMS2051F14
HMS2091B09
HMS2095E15
HMS2231G05
HMS3261E17
HMS3370K04
HMS3393F14
HMS3652H19
HMS3712E15
HMS3885D13
Pharmakon1600-01500267
BCP24067
HY-A0069
DOXYLAMINE SUCCINATE [VANDF]
Tox21_113515
Tox21_202078
Tox21_302861
Tox21_500348
CCG-38929
NSC756752
s4240
DOXYLAMINE SUCCINATE [WHO-DD]
AKOS025310916
Tox21_113515_1
AC-4487
CCG-101033
CS-3232
FD59815
LP00348
NC00283
NSC-756752
Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-, succinate (1:1)
DOXYLAMINE SUCCINATE [GREEN BOOK]
NCGC00016140-02
NCGC00016140-03
NCGC00016140-04
NCGC00021147-11
NCGC00089789-03
NCGC00093785-01
NCGC00093785-02
NCGC00093785-03
NCGC00256517-01
NCGC00259627-01
NCGC00261033-01
AS-13661
DOXYLAMINE SUCCINATE [ORANGE BOOK]
DB-052868
D5583
EU-0100348
NS00080013
SW197008-4
WLN: T6NJ BX1&R&O2N1&1 &OV2VO
C19414
D 3775
D02327
D81886
EN300-123050
SR-01000003036-2
SR-01000003036-6
SR-01000003036-9
(Dimethylamino)ethoxy-methyl-benzyl-pyridine succinate
Doxylamine.succinate, 1mg/ml in Methanol (as free base)
F2173-1155
[[[(2-Dimethylamino)ethoxy]phenyl]methyl]-2-picoline succinate
Doxylamine Hydrogen Succinate 1.0 mg/ml in Methanol (as free base)
Doxylamine succinate, United States Pharmacopeia (USP) Reference Standard
N,N-dimethyl-2-(1-phenyl-1-(pyridin-2-yl)ethoxy)ethanaminesuccinate
N,N-DIMETHYL-2-[1-PHENYL-1-(2-PYRIDINYL)ETHOXY]ETHANAMINE SUCCINATE
Phenyl2-pyridylmethyl-(.beta.-N,N-dimethylamino)ethyl ether succinate
2-[[.alpha.-(2-Dimethylamino)ethoxy]-.alpha.-methylbenzyl]pyridine succinate
Butanedioic acid,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine (1:1)
butanedioic acid; dimethyl({2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethyl})amine
Doxylamine for system suitability, European Pharmacopoeia (EP) Reference Standard
Doxylamine hydrogen succinate, European Pharmacopoeia (EP) Reference Standard
Doxylamine Succinate, Pharmaceutical Secondary Standard; Certified Reference Material
N,N-DIMETHYL-2-((1RS)-1-PHENYL-1-(PYRIDIN-2-YL)ETHOXY(ETHANAMINE HYDROGEN BUTANEDIOATE