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2-(1-Phenyl-2,3-dihydro-1H-inden-1-yl)-N,N-dimethylethanamine

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Identification
Molecular formula
C19H23N
CAS number
1095-90-5
IUPAC name
N,N-dimethyl-2-(1-phenylinden-1-yl)ethanamine
State
State

At room temperature, the compound is typically a liquid. It is not volatile but can be toxic, and care should be taken in its handling and storage.

Melting point (Celsius)
-5.00
Melting point (Kelvin)
268.15
Boiling point (Celsius)
318.50
Boiling point (Kelvin)
591.65
General information
Molecular weight
265.40g/mol
Molar mass
265.4140g/mol
Density
1.0300g/cm3
Appearence

The compound typically appears as a clear to light yellow liquid and can have a viscous consistency due to its molecular structure. It may be prone to oxidizing and changing color when exposed to air over time.

Comment on solubility

Solubility of N,N-dimethyl-2-(1-phenylinden-1-yl)ethanamine

N,N-dimethyl-2-(1-phenylinden-1-yl)ethanamine, often referred to in short as DMPI, has intriguing solubility properties that are worth exploring. The behavior of this compound in various solvents is influenced by its molecular structure, which consists of both hydrophobic and hydrophilic components.

Key Insights on Solubility:

  • Solvent Compatibility: DMPI shows varying solubility in different organic solvents, indicating that it is more soluble in non-polar solvents like hexane or toluene, while its solubility in water is quite limited.
  • Temperature Dependence: The solubility of DMPI may increase with temperature, making it more soluble at elevated temperatures, especially in organic solvents.
  • Effect of pH: The ionization states of the amine group can influence solubility; in acidic conditions, its solubility might increase due to protonation, which enhances interactions with polar solvents.

In conclusion, while DMPI is primarily non-polar and demonstrates limited water solubility, it exhibits greater solubility in a range of organic solvents. Understanding these solubility dynamics is essential for practical applications in organic synthesis and pharmaceuticals.

Interesting facts

Interesting Facts about N,N-Dimethyl-2-(1-phenylinden-1-yl)ethanamine

N,N-dimethyl-2-(1-phenylinden-1-yl)ethanamine is a fascinating chemical compound that belongs to the class of organic nitrogen compounds. It is often of interest in various scientific discussions, especially in the context of medicinal chemistry and organic synthesis.

Key Points of Interest

  • Structural Complexity: The unique structure of this compound, characterized by the presence of both an amine group and an indene moiety, contributes to its interesting chemical properties and potential biological activities.
  • Biological Relevance: Compounds similar to N,N-dimethyl-2-(1-phenylinden-1-yl)ethanamine have been explored for their potential activity in therapeutic applications, including neurological disorders. Their interactions with neurotransmitters can be an area of extensive research.
  • Synthetic Approaches: The synthesis of such compounds often involves intricate organic reactions, showcasing the creativity and precision required in modern synthetic chemistry. Techniques such as amine alkylation and catalytic transformations play a pivotal role in its production.
  • Applications in Research: This compound can serve as a useful tool in pharmacological studies, allowing scientists to probe and understand the mechanisms of action of various drugs and their effects on biological systems.
  • Analytical Techniques: Investigating the characteristics of N,N-dimethyl-2-(1-phenylinden-1-yl)ethanamine involves advanced analytical methods, including mass spectrometry and NMR spectroscopy, which help elucidate its structure and functional groups.

In summary, N,N-dimethyl-2-(1-phenylinden-1-yl)ethanamine exemplifies the intersection of organic chemistry and biological science, highlighting the importance of compound exploration in drug discovery and development. As research continues, the potential impacts of such compounds on medicine and pharmacology remain a captivating area of study.

Synonyms
INDRILINE
7395-90-6
Indriline [INN]
indrilina
UNII-J2LLI1K6QQ
J2LLI1K6QQ
1H-Indene-1-ethanamine, N,N-dimethyl-1-phenyl-
N,N-DIMETHYL-1-PHENYLINDENE-1-ETHYLAMINE
indrilinum
1H-Indene-1-ethanamine, N,N-dimethyl-1-phenyl-(9CI)
(+-)-1H-INDENE-1-ETHANAMINE, N,N-DIMETHYL-1-PHENYL-
N,N-dimethyl-2-(1-phenylinden-1-yl)ethanamine
Indrilene hydrochloride
NSC169093
LU 3-083
SCHEMBL124200
CHEMBL2110854
DTXSID90864052
NS00122755
N,N-Dimethyl-1-phenyl-1H-indene-1-ethanamine
N,N-Dimethyl-2-(1-phenyl-1H-inden-1-yl)ethanamine
N,N-Dimethyl-2-(1-phenyl-1H-inden-1-yl)ethanamine-
Q27281069
N, N-Dimethyl-1-phenylindene-1-ethylamine hydrochloride
{1-[(2-Dimethylamino)ethyl]-1-phenylindene} hydrochloride
N,N-Dimethyl-N-(2-(1-phenyl-1H-inden-1-yl)ethyl)amine
(+/-)-1H-INDENE-1-ETHANAMINE, N,N-DIMETHYL-1-PHENYL-