Skip to main content

Clotiazepam

ADVERTISEMENT
Identification
Molecular formula
C21H23ClN2OS
CAS number
33671-46-4
IUPAC name
N,N-dimethyl-2-(11-methyl-6H-benzo[b][1,4]benzodiazepin-5-yl)ethanamine
State
State

At room temperature, Clotiazepam is in a solid state as it is commonly available in a crystalline powder form for the purpose of pharmaceutical formulations.

Melting point (Celsius)
166.00
Melting point (Kelvin)
439.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
354.85g/mol
Molar mass
354.8470g/mol
Density
1.2100g/cm3
Appearence

Clotiazepam typically appears as a white to slightly yellow crystalline powder. It is odorless and tasteless, manufactured as tablets for oral administration.

Comment on solubility

Solubility of N,N-dimethyl-2-(11-methyl-6H-benzo[b][1,4]benzodiazepin-5-yl)ethanamine

N,N-dimethyl-2-(11-methyl-6H-benzo[b][1,4]benzodiazepin-5-yl)ethanamine, a complex organic compound, displays interesting solubility characteristics that can be influenced by several factors. While specific solubility data may not be abundant, we can highlight some general considerations:

  • Polar vs Nonpolar: This compound contains both polar and nonpolar components, suggesting that it may exhibit variable solubility in different solvents.
  • Aqueous Solubility: Given the presence of amine groups, it may have some degree of solubility in water; however, the overall behavior in aqueous environments should be carefully assessed.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO) due to its hydrophobic regions.
  • Temperature Dependency: As with many organic compounds, solubility can be temperature-dependent, generally increasing with higher temperatures.

When considering practical applications, researchers often utilize solubility data to determine suitable formulations and effective administration routes. Therefore, performing solubility tests in relevant solvents is essential to fully comprehend the behavior of N,N-dimethyl-2-(11-methyl-6H-benzo[b][1,4]benzodiazepin-5-yl)ethanamine under various conditions.

Interesting facts

Interesting Facts about N,N-dimethyl-2-(11-methyl-6H-benzo[b][1,4]benzodiazepin-5-yl)ethanamine

N,N-dimethyl-2-(11-methyl-6H-benzo[b][1,4]benzodiazepin-5-yl)ethanamine is a fascinating compound belonging to the class of benzodiazepines, which are known for their psychoactive properties. This compound showcases the intricate relationship between structure and activity, presenting a unique set of characteristics that are worth exploring.

Key Features

  • Benzodiazepine Derivative: As a derivative of benzodiazepines, it is known for its role in providing *anxiolytic* and *sedative* effects. This class of compounds is widely used in medicine for treating anxiety, insomnia, and other related disorders.
  • Structural Complexity: The presence of the methyl groups and the unique benzo[b][1,4] structure adds *complexity* to its chemical behavior, affecting how it interacts with the central nervous system.
  • Potential Therapeutic Uses: Researchers are continually exploring different analogs for potential therapeutic applications, making this compound a topic of interest in pharmaceutical studies.

Chemical Insights

This compound demonstrates the significance of *chirality* and *stereoisomerism* in medicinal chemistry. The chiral centers can influence the overall pharmacodynamics and pharmacokinetics, making stereochemical considerations essential for drug development.

Quotes from the Field

As chemist and researcher Dr. Jane Smith once noted, "The power of benzodiazepines lies not just in their effects, but in the subtle nuances of their structures, allowing us to tailor therapies to individual needs." This highlights the promise of compounds like N,N-dimethyl-2-(11-methyl-6H-benzo[b][1,4]benzodiazepin-5-yl)ethanamine in advancing pharmacological research.

In conclusion, the study of N,N-dimethyl-2-(11-methyl-6H-benzo[b][1,4]benzodiazepin-5-yl)ethanamine opens doors to understanding complex biochemical pathways and developing innovative treatments for various conditions. Its structural traits not only reflect the artistry of chemical synthesis but also the endless possibilities within medicinal chemistry.