Lidocaine | Solubility of Things

Identification

Molecular formula

C₁₄H₂₂N₂O

CAS number

137-58-6

IUPAC name

N,N-dimethyl-2-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)acetamide

State

At room temperature, lidocaine is typically in a solid state, often encountered as a crystal or powder. When used in medical formulations, it can be found in liquid solutions.

Melting point (Celsius)

68.00

Melting point (Kelvin)

341.15

Boiling point (Celsius)

180.00

Boiling point (Kelvin)

453.15

General information

Molecular weight

234.34g/mol

Molar mass

234.3390g/mol

Density

1.0260g/cm³

Appearence

Lidocaine typically appears as a white crystalline powder. It can also be found in the form of a solution when used in medical applications. In its powder form, it is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of N,N-dimethyl-2-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)acetamide

The solubility of N,N-dimethyl-2-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)acetamide is influenced by its unique structural features and the presence of functional groups. Understanding its solubility is crucial for applications in pharmaceuticals and chemical formulations. Here are some key points to consider:

Polarity: The compound exhibits polar characteristics due to the presence of the acetamide group, which tends to increase solubility in polar solvents like water.
Hydrogen Bonding: The ability to form hydrogen bonds can further enhance solubility, particularly in protic solvents.
Alkyl Groups: The bulky trimethyl groups may impart hydrophobic properties, which can influence overall solubility in organic solvents.
Temperature Influence: As with many organic compounds, solubility may improve with an increase in temperature, promoting greater molecular interaction.

In summary, **solubility** is likely to be moderate in water but can vary significantly in organic solvents, emphasizing the need to examine specific solvent interactions. As one expert put it, "The key to understanding solubility lies in recognizing the balance of polar and nonpolar interactions."

Interesting facts

Interesting Facts about N,N-Dimethyl-2-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)acetamide

N,N-Dimethyl-2-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)acetamide, commonly known for its complex structure and unique properties, is a fascinating compound in the field of organic chemistry. Here are some intriguing insights into this molecule:

Complex Structure: This compound features a bicyclic framework, incorporating a nitrogen atom in its structure, which contributes to its biological activity and physical properties.
Pharmacological Potential: Due to its structural resemblance to various neurotransmitters, it is being studied for potential applications in pharmaceutical chemistry, particularly in developing drugs that target the nervous system.
Chirality: The presence of multiple chiral centers makes this compound a subject of interest for stereochemistry studies, as different stereoisomers can exhibit differing biological activities.
Natural Analogues: Compounds similar to N,N-dimethyl-2-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)acetamide are often found in various natural sources, pointing towards their relevance in medicinal chemistry and drug development.
Research Opportunities: The various functional groups present in its structure give rise to numerous opportunities for synthetic modifications, making it a versatile compound for further research.

As science continues to delve deeper into the complexities of organic compounds like N,N-dimethyl-2-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)acetamide, it opens up avenues for innovation in both industrial applications and therapeutic approaches. The synergy between organic chemistry and pharmacology highlights the importance of such compounds in advancing health sciences.