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Pimavanserin

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Identification
Molecular formula
C25H34N4
CAS number
706769-91-1
IUPAC name
N,N-dimethyl-2-[2-[2-(1-piperidyl)ethyl]benzimidazol-1-yl]propan-1-amine
State
State

At room temperature, pimavanserin is in the form of a solid. It is typically handled as a powder in pharmaceutical applications.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
524.30
Boiling point (Kelvin)
797.35
General information
Molecular weight
427.58g/mol
Molar mass
427.5820g/mol
Density
1.1096g/cm3
Appearence

Pimavanserin typically appears as a white to off-white powder. It is generally odorless and can be difficult to distinguish by appearance alone without proper labeling and container information.

Comment on solubility

Solubility of N,N-dimethyl-2-[2-[2-(1-piperidyl)ethyl]benzimidazol-1-yl]propan-1-amine

N,N-dimethyl-2-[2-[2-(1-piperidyl)ethyl]benzimidazol-1-yl]propan-1-amine, while a complex compound, presents intriguing features when it comes to its solubility. Understanding solubility is crucial in various chemical applications, including pharmacology and material science. Here are some key insights:

  • Polarity: The solubility of compounds often correlates with their polarity. This specific compound contains both amine and benzimidazolyl groups, which can influence its interaction with solvents.
  • Solvent Compatibility: In general, this compound may be expected to demonstrate higher solubility in polar solvents like water or alcohols due to the presence of polar functional groups.
  • Hydrogen Bonding: The ability to form hydrogen bonds greatly enhances solubility. The amine group in the structure facilitates this, potentially increasing its affinity for polar solvents.
  • Structural Considerations: The steric hindrance from the dimethyl and piperidyl groups might affect solubility by limiting interactions with solvent molecules.

It’s essential to note that experimental data would provide the most reliable insight into its actual solubility behavior. Understanding solubility not only assists in predicting the behavior of the compound in various environments but also aids in its practical applications.

Interesting facts

Interesting Facts about N,N-dimethyl-2-[2-[2-(1-piperidyl)ethyl]benzimidazol-1-yl]propan-1-amine

N,N-dimethyl-2-[2-[2-(1-piperidyl)ethyl]benzimidazol-1-yl]propan-1-amine, a complex organic compound, is known for its intriguing properties and applications. Here are some fascinating insights into this compound:

  • Pharmacological Potential: This compound is often studied for its potential therapeutic applications, particularly in the fields of psychiatry and neurology. Its structural motifs are similar to known stimulant and psychoactive substances.
  • Benzimidazole Framework: The benzimidazole structure is significant because compounds with this scaffold have demonstrated a variety of biological activities, including antimicrobial and anticancer properties.
  • Piperidine Influence: The presence of the piperidyl moiety contributes to the compound’s ability to interact with various receptors in the brain, which is crucial for developing drugs that can affect mood and behavior.
  • Synthesis Challenge: Synthesizing such a complex compound involves multi-step reactions, showcasing advanced techniques in organic chemistry. This highlights the importance of innovative methods in modern pharmaceutical research.

Quote: "The beauty of chemistry lies in its ability to bring together small molecules to create larger, impactful solutions." This compound exemplifies that beauty, connecting different chemical elements to potentially address significant health challenges.

In conclusion, N,N-dimethyl-2-[2-[2-(1-piperidyl)ethyl]benzimidazol-1-yl]propan-1-amine stands at the intersection of organic synthesis and medicinal chemistry, representing the fun and complexity inherent in the world of chemical compounds.