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Sertraline

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Identification
Molecular formula
C17H26N4
CAS number
118036-22-1
IUPAC name
N,N-dimethyl-2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propan-1-amine
State
State
Sertraline at room temperature is a solid.
Melting point (Celsius)
246.50
Melting point (Kelvin)
519.70
Boiling point (Celsius)
515.30
Boiling point (Kelvin)
788.50
General information
Molecular weight
306.45g/mol
Molar mass
306.4460g/mol
Density
1.3100g/cm3
Appearence

Sertraline is typically a white crystalline powder. It may sometimes appear as an off-white powder depending on the specific sample and purity.

Comment on solubility

Solubility of N,N-dimethyl-2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propan-1-amine

The solubility of N,N-dimethyl-2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propan-1-amine is a subject of interest due to its structural characteristics. This compound exhibits unique solubility behavior which can be analyzed in relation to its functional groups and molecular structure. Key points regarding its solubility include:

  • Polarity: The presence of nitrogen atoms and an aromatic ring may influence polarity, allowing for solubility in polar solvents like water and alcohols.
  • Hydrophilicity and Hydrophobicity: The molecule contains both hydrophilic (polar) and hydrophobic (non-polar) regions, indicating that it may display different solubility characteristics depending on the solvent used.
  • Temperature Dependence: Solubility may vary significantly with temperature; typically, increased temperature can lead to higher solubility for solids and liquids.
  • Potential Interactions: The formation of hydrogen bonds with solvents, particularly in aqueous solutions, can augment solubility.

In summary, while the exact solubility of N,N-dimethyl-2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propan-1-amine in various solvents may require empirical measurement, it is expected to show moderate to good solubility characteristics due to its balanced structure.

Interesting facts

Interesting Facts about N,N-Dimethyl-2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propan-1-amine

N,N-Dimethyl-2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propan-1-amine is a fascinating compound that has garnered interest in various fields, particularly medicinal chemistry. Here are some key points that highlight its significance:

  • Structural Complexity: This compound features a complex structure that combines a benzimidazole ring, which is known for its biological activity, with a pyrrolidine moiety. The unique interplay of these functional groups can lead to interesting pharmacological properties.
  • Potential Therapeutic Uses: The structural motifs present in this compound make it a potential candidate for drug development. Compounds that contain benzimidazole rings have been studied for their anti-cancer, anti-inflammatory, and antimicrobial properties.
  • Chemical Diversity: This compound exemplifies the trend of designing multifunctional molecules, where one compound can potentially exhibit multiple effects. Chemists are increasingly focusing on such compounds in the hope of creating more effective therapeutic agents.
  • Research Applications: Due to its unique structure, this compound is likely of interest in the field of neuroscience, especially concerning the modulation of neurotransmitter receptors. Research on related compounds has provided insights into behavioral pharmacology.
  • Complex Synthesis: The synthesis of such intricate molecules often involves multiple steps and the use of advanced techniques, such as asymmetric synthesis and the use of protecting groups, reflecting the challenges faced by synthetic chemists.
  • Multidisciplinary Interest: Beyond medicinal applications, compounds of this nature attract attention from fields like material science and nanotechnology, where researchers explore their potential as building blocks for novel materials.

The exploration of N,N-dimethyl-2-[2-(2-pyrrolidin-1-ylethyl)benzimidazol-1-yl]propan-1-amine and similar compounds is a vivid illustration of how chemistry intertwines with biology and medicine, highlighting the importance of interdisciplinary research in addressing complex scientific challenges.