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1-Methylpsilocin

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Identification
Molecular formula
C12H14N2O2
CAS number
2580-04-1
IUPAC name
N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide
State
State

At room temperature, N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide is typically in a solid state.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
419.15
Boiling point (Kelvin)
692.30
General information
Molecular weight
244.29g/mol
Molar mass
244.2800g/mol
Density
1.2000g/cm3
Appearence

N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide

N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide, often abbreviated for convenience, exhibits a unique solubility profile that is of great interest in various chemical applications.

This compound shows moderate solubility in polar solvents, such as:

  • Water: Limited due to hydrophobic indole components.
  • Ethanol: Soluble, enhancing its utility in biochemical applications.
  • Dimethyl sulfoxide (DMSO): Highly soluble, making it suitable for laboratory environments.

In contrast, its solubility in non-polar solvents is significantly less favorable. This can be attributed to the compound's structural characteristics:

  1. The presence of polar functional groups that interact with polar solvents.
  2. The bulky indole ring, which hinders solubility in non-polar environments.

As a result, researchers should consider using polar aprotic solvents for optimal dissolution during experiments. Overall, the solubility characteristics of this compound make it an intriguing subject for further investigation, especially in the fields of medicinal chemistry and drug formulation.

Interesting facts

Exploring N,N-Dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide

N,N-Dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide is a fascinating compound with a variety of potential applications in the field of medicinal chemistry. Here are some noteworthy aspects:

  • Unique Structure: This compound features an indole moiety, which is significant in various natural products and pharmaceuticals. Indole structures are known for their ability to engage in diverse biological activities.
  • Role in Drug Discovery: Compounds with indole frameworks, similar to N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide, have been explored extensively for their antitumor, antimicrobial, and anti-inflammatory properties, showcasing their relevance in drug development.
  • Synthetic Interest: The synthesis of this compound showcases interesting synthetic routes, which can involve reactions such as acylation and alkylation, making it an excellent subject for organic chemistry enthusiasts.
  • Biological Implications: Researchers are investigating the interactions of this compound with biological systems, particularly its potential effects on neurotransmitter systems, which may have implications for neurological disorders.
  • Potential for Further Research: As the scientific community dives deeper into the properties of N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide, its effectiveness and potential side effects remain the focus of ongoing studies, with much to learn about its pharmacological profile.

In summary, N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxo-acetamide is a compound rich in chemical intrigue and biological potential, making it a compelling topic for both research and application in the realm of pharmaceuticals.

Synonyms
1084-47-5
INDOLE-3-GLYOXYLAMIDE, N,N,2-TRIMETHYL-
N,N,2-Trimethylindole-3-glyoxylamide
NSC 70728
BRN 0478988
DTXSID60148533
5-22-06-00325 (Beilstein Handbook Reference)
DTXCID7071024
N,N-dimethyl-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide
1H-Indole-3-acetamide,N,N,2-trimethyl-a-oxo-
NSC70728
NCIOpen2_003223
NSC-70728
AKOS022506691
SR-01000098571
SR-01000098571-1
F0675-0236