Skip to main content

Diphenhydramine

ADVERTISEMENT
Identification
Molecular formula
C17H21NO
CAS number
58-73-1
IUPAC name
N,N-dimethyl-2-(2-phenylethoxy)ethanamine
State
State

At room temperature, diphenhydramine is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
307.10
Boiling point (Kelvin)
580.25
General information
Molecular weight
255.36g/mol
Molar mass
255.3480g/mol
Density
1.0000g/cm3
Appearence

Diphenhydramine appears as a white, crystalline powder that is practically odorless and has a bitter taste.

Comment on solubility

Solubility of N,N-dimethyl-2-(2-phenylethoxy)ethanamine

N,N-dimethyl-2-(2-phenylethoxy)ethanamine, often known for its unique structural properties, exhibits noteworthy solubility characteristics that can influence its applications in various fields. Understanding its solubility is key to manipulating its behavior in chemical reactions and formulations.

General Solubility Profile

This compound is primarily soluble in organic solvents due to its hydrophobic aromatic components and the presence of a dimethylamino group. Here are some insights into its solubility:

  • Solvents: It is notably soluble in nonpolar and polar aprotic solvents like ethanol, methanol, and acetone.
  • Water Solubility: It exhibits limited solubility in water, which is common for compounds featuring large organic moieties.

Factors Influencing Solubility

The solubility of N,N-dimethyl-2-(2-phenylethoxy)ethanamine can be influenced by several factors:

  • Temperature: Generally, an increase in temperature can enhance solubility.
  • pH Level: The solubility can also vary significantly depending on the ionic environment, especially in the presence of acids or bases.
  • Presence of Other Solutes: Co-solvents or solutes can facilitate or hinder solubility through interactions.

In conclusion, while N,N-dimethyl-2-(2-phenylethoxy)ethanamine is not highly soluble in water, its solubility in organic solvents makes it a versatile compound for various applications. Its distinctive structure grants it unique solubility traits that can be harnessed in experimental settings. As the saying goes, "Being aware of solubility dynamics can lead to significant breakthroughs in chemical applications."

Interesting facts

Interesting Facts about N,N-dimethyl-2-(2-phenylethoxy)ethanamine

N,N-dimethyl-2-(2-phenylethoxy)ethanamine is an intriguing compound that merges the realms of organic chemistry with potential applications in pharmacology. Here are some engaging insights about this compound:

  • Pharmacological Interest: This compound is notable for its potential role as a neurotransmitter or as a precursor to biologically active molecules. Understanding its structure can provide insights into how similar compounds influence neurological functions.
  • Structural Versatility: With both a dimethylamine and a phenylethoxy group, this compound exemplifies structural diversity. Such variations can significantly impact a compound's reactivity and interactions, making it a valuable study in structure-activity relationships.
  • Synthesis Challenges: The synthesis of N,N-dimethyl-2-(2-phenylethoxy)ethanamine involves intricate organic reactions, highlighting the challenges chemists face when designing multifunctional molecules. This can inspire students to explore various synthetic pathways and techniques.
  • Research Potential: The compound's distinctive properties can make it an attractive candidate for research in medicinal chemistry, possibly yielding new therapeutic agents or drugs designed to target specific receptor sites in the brain.

As one delves into the study of N,N-dimethyl-2-(2-phenylethoxy)ethanamine, it becomes clear that the compound is more than just a collection of atoms. It represents a bridge between fundamental chemical principles and real-world applications that can drive scientific progress.

Synonyms
BRN 2441701
ETHYLAMINE, N,N-DIMETHYL-2-(PHENETHYLOXY)-
N,N-Dimethyl-2-(phenethyloxy)ethylamine
26281-48-1
DTXSID80180910
RefChem:345202
DTXCID20103401