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Clofazimine

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Identification
Molecular formula
C27H22Cl2N4
CAS number
2030-63-9
IUPAC name
N,N-dimethyl-2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxy-ethanamine
State
State

At room temperature, clofazimine is typically in a solid state, present as a powder which is used in pharmaceutical preparations.

Melting point (Celsius)
212.70
Melting point (Kelvin)
485.85
Boiling point (Celsius)
283.00
Boiling point (Kelvin)
556.15
General information
Molecular weight
473.40g/mol
Molar mass
473.3980g/mol
Density
0.9296g/cm3
Appearence

Clofazimine appears as a red crystalline powder, which can exhibit a red to purple hue. It is often characterized by its distinct color, which can vary slightly depending on the crystallization process.

Comment on solubility

Solubility of N,N-dimethyl-2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxy-ethanamine

The solubility characteristics of the compound N,N-dimethyl-2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxy-ethanamine can be rather complex due to its unique structural features and the presence of multiple functional groups.

Key Factors Affecting Solubility:

  • Polarity: The degree of polarity in the molecule significantly influences its solubility in various solvents. The presence of amino and ether groups often increases polarity, enhancing solubility in polar solvents.
  • Hydrophobic Interactions: The tricyclic structure may impart hydrophobic characteristics, which can limit solubility in aqueous environments.
  • Effect of Substituents: Substituents on the nitrogen atoms and the overall steric bulk can create steric hindrance, which may affect solubility.
  • Temperature and pH: Solubility can vary with temperature changes and the pH of the solution, making it important to consider these factors in practical applications.

In summary, the solubility of this compound is likely to be moderate in polar solvents, while it may exhibit limited solubility in non-polar solvents due to its unique combination of hydrophilic and hydrophobic characteristics. As a result, it is important to conduct experimental solubility tests to determine the solubility profile in specific solvents for practical applications.

Interesting facts

Interesting Facts about N,N-Dimethyl-2-(2-Tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxy-ethanamine

This intriguing compound is a remarkable example of organic chemistry, showcasing both complexity and potential applications in various fields. Here are some fascinating aspects:

  • Unique Structure: The compound features a distinctive tricyclic structure, which adds to its molecular complexity. The tricyclo[9.4.0.03,8] system is particularly interesting due to its intricate connectivity which influences the compound's reactivity and stability.
  • Potential Biological Activity: Compounds with similar structural motifs have been investigated for their biological activities. There is ongoing research into their applications in pharmaceuticals, especially in targeting specific biological pathways.
  • Versatile Functional Group: The presence of the dimethylamine and ether functional groups suggests potential for engaging in a variety of chemical reactions, allowing chemists to modify and optimize the compound for diverse uses.
  • Role in Material Science: The unique properties attributed to such complex structures could drive innovations in materials chemistry, influencing the development of new polymers or composites with notable strength and flexibility.
  • Research and Development: This compound exemplifies the frontier of experimental chemistry where researchers are continually exploring the intricacies of organic compounds, paving the way for advancements in drug design and molecular engineering.

In summary, N,N-dimethyl-2-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylideneamino)oxy-ethanamine not only serves as a testament to the beauty of organic synthesis but also opens avenues for future research and application in various scientific disciplines.