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Venlafaxine

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Identification
Molecular formula
C17H27NO2
CAS number
93413-69-5
IUPAC name
N,N-dimethyl-2-(5-phenylisoxazol-3-yl)ethanamine
State
State

At room temperature, venlafaxine is typically in a solid crystalline state.

Melting point (Celsius)
207.00
Melting point (Kelvin)
480.15
Boiling point (Celsius)
523.30
Boiling point (Kelvin)
796.45
General information
Molecular weight
277.39g/mol
Molar mass
277.3920g/mol
Density
1.1921g/cm3
Appearence

Venlafaxine is typically found as a crystalline solid. It appears as a white to off-white powder that is practically odorless. The powder is also known for its bitter taste.

Comment on solubility

Solubility of N,N-dimethyl-2-(5-phenylisoxazol-3-yl)ethanamine

N,N-dimethyl-2-(5-phenylisoxazol-3-yl)ethanamine is a compound whose solubility can be rather nuanced. Understanding its solubility characteristics is essential when considering its application in various chemical environments. Here’s what you need to know:

  • Polar vs. Non-Polar Solvents: The presence of both a dimethylamine group and a phenylisoxazole structure suggests that this compound may display varying solubility in different solvents. It is likely to be soluble in polar solvents such as water and alcohol due to the polar nature of the amine group.
  • Temperature Effects: As with many organic compounds, solubility can be significantly affected by temperature. An increase in temperature can enhance solubility for many compounds, including this one.
  • pH Dependence: The solubility of amines can be influenced by pH changes. In acidic conditions, the amine group may become protonated, potentially increasing solubility in water.
  • Hydrophobic Effects: The phenyl part of the molecule could create hydrophobic interactions, making it less soluble in water and preferentially soluble in non-polar organic solvents.

In conclusion, the solubility of N,N-dimethyl-2-(5-phenylisoxazol-3-yl)ethanamine is a complex interplay of molecular structure and environmental conditions. It's crucial to consider these factors when looking to utilize this compound in research or industrial applications.

Interesting facts

Interesting Facts about N,N-dimethyl-2-(5-phenylisoxazol-3-yl)ethanamine

N,N-dimethyl-2-(5-phenylisoxazol-3-yl)ethanamine is a fascinating compound that showcases the interplay between organic synthesis and medicinal chemistry. Here are some intriguing insights into this compound:

  • Structural Complexity: This compound features a unique isoxazole ring, which is a five-membered aromatic heterocycle containing both oxygen and nitrogen atoms. Such structures are known for exhibiting interesting diverse biological activities.
  • Pharmacological Potential: Compounds featuring the isoxazole moiety are often studied for their potential as pharmaceuticals, including as antitumor, anti-inflammatory, and analgesic agents. The presence of a phenyl group further enhances its ability to interact with biological targets.
  • Chemical Versatility: The dimethylamine group in the structure contributes to its chemical reactivity, making it versatile in organic reactions. This property allows for a variety of derivatives to be synthesized, which can lead to various functional applications.
  • Research Applications: Researchers are continually exploring compounds like this one, particularly in the realms of neuropharmacology. The ability of such compounds to cross the blood-brain barrier adds to their significance in developing treatments for neurological disorders.
  • Inspiration for Synthesis: The synthesis of this compound often serves as an excellent example for students and chemists alike. It embodies a multi-step synthetic pathway that highlights the importance of functional group transformations in organic chemistry.

As the exploration of such compounds advances, N,N-dimethyl-2-(5-phenylisoxazol-3-yl)ethanamine stands out as a compound of interest, merging the worlds of chemical research and practical medicinal application. The potential it holds illustrates the power of chemistry to innovate and influence human health.