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Desloratadine

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Identification
Molecular formula
C19H19ClN2O
CAS number
100643-71-8
IUPAC name
N,N-dimethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)propan-1-amine
State
State

At room temperature, Desloratadine is usually in a solid state. It is provided as a crystalline powder and is stable under normal conditions when stored properly.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
484.60
Boiling point (Kelvin)
757.80
General information
Molecular weight
310.81g/mol
Molar mass
310.8140g/mol
Density
1.0800g/cm3
Appearence

Desloratadine is a white to off-white crystalline powder. It is typically very fine and may exhibit a slight sheen due to its crystalline nature. The compound is usually packed in opaque or amber containers to protect it from light exposure, which can lead to degradation.

Comment on solubility

Solubility of N,N-dimethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)propan-1-amine

The solubility of N,N-dimethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)propan-1-amine can be intriguing due to its complex structure. This compound features a quinoline moiety that can influence its solubility properties. Here are some key points to consider:

  • Polarity: The presence of an amine functional group typically suggests a degree of polarity, which can enhance solubility in polar solvents such as water or ethanol.
  • Hydrophobic Interactions: The cycloheptane system may introduce hydrophobic characteristics, potentially reducing solubility in aqueous environments while increasing solubility in organic solvents like chloroform or dichloromethane.
  • Temperature Influence: Solubility can be temperature dependent; thus, an increase in temperature may improve solubility in certain solvents due to increased molecular motion.
  • Interactions: Possible hydrogen bonding between the amine group and solvents can further affect solubility, where strong interactions may enhance solubility in specific polar solvents.

In summary, the solubility of this compound is likely to be influenced by a balance between its hydrophilic amine group and the hydrophobic cyclic structure. As a result, a detailed study involving various solvents and conditions would be essential to accurately determine its solubility profile.

Interesting facts

Exploring N,N-Dimethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)propan-1-amine

The compound N,N-dimethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)propan-1-amine is a fascinating member of a class of compounds known for their diverse biological activities. Below are some intriguing facts about this compound:

  • Complex Structure: This compound features a unique bicyclic structure that contributes to its potential biological properties. The presence of the tetrahydro-cycloheptquinoline moiety enhances its structural complexity, allowing for interesting interactions within biological systems.
  • Biological Interest: Compounds of this type may exhibit properties that are useful in medicinal chemistry. Their structure can lead to interactions with various biological targets, making them potential candidates for drug development.
  • Dimethylamine Functionality: The N,N-dimethylamino group can significantly influence the compound's physicochemical properties, including its lipophilicity and ability to cross biological membranes.
  • Potential Applications: Researchers are interested in examining the potential use of this compound in neuropharmacology due to its possible interactions with neurotransmitter systems.
  • Cross-Disciplinary Relevance: This compound exemplifies the intersection of synthetic organic chemistry and pharmacology, providing a rich area for study and experimentation.

In conclusion, N,N-dimethyl-2-(7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yloxy)propan-1-amine is not only an intriguing structure but also holds promise for advancements in drug discovery and development. As scientists continue to explore its properties, we may uncover new therapeutic avenues that could impact the medical field.