Skip to main content

Benzydamine

ADVERTISEMENT
Identification
Molecular formula
C19H23NO
CAS number
642-72-8
IUPAC name
N,N-dimethyl-2-[m-tolyl(phenyl)methoxy]ethanamine
State
State

At room temperature, benzydamine is typically found in a solid state. It is often handled in its salt form, such as benzydamine hydrochloride.

Melting point (Celsius)
164.50
Melting point (Kelvin)
437.70
Boiling point (Celsius)
345.70
Boiling point (Kelvin)
618.90
General information
Molecular weight
309.44g/mol
Molar mass
309.4430g/mol
Density
1.0505g/cm3
Appearence

Benzydamine appears as a white crystalline powder. It is commonly used in its hydrochloride salt form, which can appear with a similar white crystalline appearance.

Comment on solubility

Solubility of N,N-dimethyl-2-[m-tolyl(phenyl)methoxy]ethanamine

N,N-dimethyl-2-[m-tolyl(phenyl)methoxy]ethanamine presents a complex behavior in terms of solubility. It is important to note that the solubility of this compound can be influenced by various factors including the presence of functional groups, temperature, and the type of solvent used.

Key Characteristics of Solubility:

  • Polar and Non-polar Nature: The presence of both polar and non-polar groups in its structure results in a mixed solubility profile. This compound may show appreciable solubility in organic solvents such as toluene or chloroform.
  • Temperature Dependence: Like many organic compounds, solubility may increase with temperature. Therefore, testing solubility at different temperatures can yield varying results.
  • Hydrogen Bonding: The capability of the compound to engage in hydrogen bonding can enhance its solubility in polar solvents like alcohols.

However, when dissolved in aqueous solutions, the compound may exhibit limited solubility due to its hydrophobic aromatic groups. This leads to a general trend where:

  • The compound is likely to be sparingly soluble in water.
  • Its solubility in non-polar organic solvents will be significantly higher.

Overall, the solubility of N,N-dimethyl-2-[m-tolyl(phenyl)methoxy]ethanamine highlights the intricate balance between its structural features and the solvation environment, making it a fascinating subject for further investigation.

Interesting facts

Interesting Facts about N,N-dimethyl-2-[m-tolyl(phenyl)methoxy]ethanamine

N,N-dimethyl-2-[m-tolyl(phenyl)methoxy]ethanamine is a fascinating compound with connections to various fields, including organic synthesis, pharmacology, and materials science. Here are some interesting insights into this compound:

  • Structural Complexity: This compound showcases a complex molecular structure that includes both aromatic and aliphatic components. The presence of the m-tolyl group, a derivative of toluene, adds to its unique properties and potential applications.
  • Biological Activity: Compounds with similar structural motifs have been studied for their pharmacological properties. Researchers often explore how variations in the ethylamine backbone influence biological activity, particularly in areas such as neurology and psycho-pharmacology.
  • Applications in Synthesis: The methoxy group in this compound can act as a functional handle for further chemical modifications. This makes it an important intermediate in the synthesis of more complex molecules, which may have industrial or medicinal applications.
  • Mechanistic Insights: Understanding how this compound interacts with biological systems can provide insights into receptor binding mechanisms. Compounds of this nature often require thorough analysis through techniques such as NMR spectroscopy and mass spectrometry.
  • Research Perspectives: Ongoing research may focus on the **pharmacokinetics** and **toxicology** of this compound, investigating its behavior in living organisms and determining its safety profile for potential therapeutic uses.

As science continues to evolve, compounds like N,N-dimethyl-2-[m-tolyl(phenyl)methoxy]ethanamine present exciting opportunities for discovery and innovation. Whether you're enhancing our understanding of molecular interactions or synthesizing novel materials, the study of such compounds remains a critical aspect of modern chemistry.

Synonyms
O-Demethyl-m-methyl orphenadrine
21945-86-8
Orphenadrine impurity E
3-Methyldiphenhydramine
A40KR91PE2
Orphenadrine meta-methylbenzyl isomer
Orphenadrine citrate impurity E [EP]
(RS)-N,N-Dimethyl-2-((3-methylphenyl)phenylmethoxy)ethanamine
Ethanamine, N,N-dimethyl-2-((3-methylphenyl)phenylmethoxy)-
Orphenadrine citrate specified impurity E [EP]
Ethylamine, N,N-dimethyl-2-((m-methyl-alpha-phenylbenzyl)oxy)-
ORPHENADRINE CITRATE IMPURITY E [EP IMPURITY]
ETHYLAMINE, N,N-DIMETHYL-2-((M-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-
ORPHENADRINE CITRATE IMPURITY E (EP IMPURITY)
Orphenadrine citrate impurity E
Orphenadrine citrate specified impurity E
110-989-1
N,N-dimethyl-2-[(3-methylphenyl)-phenylmethoxy]ethanamine
UNII-A40KR91PE2
AM-814/41091386
WAA94586
Q27273594
N,N-Dimethyl-2-[(3-methylphenyl)phenylmethoxy]ethanamine
N,N-dimethyl-N-{2-[(3-methylphenyl)(phenyl)methoxy]ethyl}amine