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Tamsulosin hydrochloride

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Identification
Molecular formula
C20H28ClNO2S
CAS number
106133-20-4
IUPAC name
N,N-dimethyl-2-[o-tolyl(phenyl)methoxy]ethanamine oxide
State
State

Tamsulosin hydrochloride is in a solid state under room temperature conditions, commonly formulated in tablet or capsule for medicinal use.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
408.98g/mol
Molar mass
408.5030g/mol
Density
1.2022g/cm3
Appearence

Tamsulosin hydrochloride typically appears as a white to off-white crystalline powder. It may exhibit polymorphism depending on the conditions of crystallization and processing.

Comment on solubility

Solubility of N,N-dimethyl-2-[o-tolyl(phenyl)methoxy]ethanamine oxide

The solubility of N,N-dimethyl-2-[o-tolyl(phenyl)methoxy]ethanamine oxide can be influenced by various factors, including its structural properties and the nature of the solvent.

Factors affecting solubility:

  • Polarity: The presence of both hydrophilic and hydrophobic groups in the molecule can lead to varied solubility in different solvents. Compounds with significant hydrophobic character often dissolve well in organic solvents.
  • Temperature: Generally, increasing the temperature can improve solubility, particularly in organic solvents.
  • pH: As an amine oxide, the protonation state of the amine nitrogen can also affect solubility in aqueous environments.
  • Interaction with Solvents: The degree of interaction that the compound has with potential solvents (such as polar versus non-polar solvents) plays a crucial role in determining its solubility.

Potential solubility could be expressed in terms of ranges such as:

  • Very soluble: > 1000 mg/mL
  • Soluble: 100 - 1000 mg/mL
  • Practically insoluble: < 1 mg/mL

In conclusion, while predicting the exact solubility of N,N-dimethyl-2-[o-tolyl(phenyl)methoxy]ethanamine oxide in various solvents can be complex, the combination of its chemical structure and environmental conditions play decisive roles. Therefore, empirical measurement remains essential for accurate solubility data.

Interesting facts

Interesting Facts about N,N-dimethyl-2-[o-tolyl(phenyl)methoxy]ethanamine oxide

N,N-dimethyl-2-[o-tolyl(phenyl)methoxy]ethanamine oxide is a fascinating compound that belongs to a class of chemicals known as amines. Here are some intriguing facts about this compound:

  • Structure and Function: This compound features a complex structure that includes both aromatic (o-tolyl and phenyl) and aliphatic components, making it a versatile molecule in various chemical reactions.
  • Potential Applications: Its unique structure suggests potential applications in pharmaceuticals, agrochemicals, and other industrial sectors where functionality is key. The incorporation of different functional groups can lead to a variety of biological activities.
  • Oxide Formation: The presence of the oxide group makes it an interesting subject for chemists studying electron-donating and electron-withdrawing effects, impacting the overall reactivity and interaction of the compound.
  • Synthesis Challenges: Due to its complex structure, synthesizing N,N-dimethyl-2-[o-tolyl(phenyl)methoxy]ethanamine oxide may require advanced techniques and careful attention to reaction conditions, making it a valuable learning experience for aspiring chemists.
  • Research Potential: With ongoing research into derivatives of amine oxides, this compound could be a stepping stone for new discoveries in drug design and development.

In summary, the study of N,N-dimethyl-2-[o-tolyl(phenyl)methoxy]ethanamine oxide not only expands our understanding of amine oxides but also illustrates the intersection of organic chemistry and real-world applications in a myriad of fields. As a molecular architect, a deep dive into its properties could pave the way for innovative solutions in chemistry.

Synonyms
Orphenadrine N-oxide
29215-00-7
BRN 2538746
N,N-Dimethyl-2-((o-methyl-alpha-phenylbenzyl)oxy)ethylamine N-oxide
ETHYLAMINE, N,N-DIMETHYL-2-((o-METHYL-alpha-PHENYLBENZYL)OXY)-, N-OXIDE
N,N-Dimethyl-2-((o-methyl-.alpha.-phenylbenzyl)oxy)ethylamine N-oxide
Ethylamine, N,N-dimethyl-2-((o-methyl-.alpha.-phenylbenzyl)oxy)-, N-oxide
RefChem:366988
XMSSICJSZNPVFX-UHFFFAOYSA-N
N,N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine oxide
N,N-Dimethyl-2-[(o-methyl-alpha-phenylbenzyl)oxy]ethanamine N-oxide
N,N-Dimethyl-2-[(2-methylphenyl)phenylmethoxy]ethanamine N-Oxide; N,N-Dimethyl-2-[(o-methyl-?-phenylbenzyl)oxy]ethylamine N-Oxide;
N,N-Dimethyl-2-[(2-methylphenyl)phenylmethoxy]ethanamine N-Oxide
DTXSID90951815
NS00114059
Dimethyl(2-[(2-methylphenyl)(phenyl)methoxy]ethyl)amine oxide #
N,N-Dimethyl-2-[(2-methylphenyl)(phenyl)methoxy]ethan-1-amine N-oxide