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Metaxalone

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Identification
Molecular formula
C12H15NO2
CAS number
1665-48-1
IUPAC name
N,N-dimethyl-2-[phenyl(p-tolyl)methoxy]ethanamine
State
State

At room temperature, Metaxalone exists in the form of a solid substance, typically processed into tablet form for medical use.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
343.00
Boiling point (Kelvin)
616.15
General information
Molecular weight
221.33g/mol
Molar mass
221.3280g/mol
Density
1.2180g/cm3
Appearence

Metaxalone is typically a white, crystalline powder. It is practically odorless and has a very slight bitter taste. Once processed into tablet form, it appears as a standard oblong pill, often coated for easier consumption.

Comment on solubility

Solubility of N,N-dimethyl-2-[phenyl(p-tolyl)methoxy]ethanamine

N,N-dimethyl-2-[phenyl(p-tolyl)methoxy]ethanamine, with its complex structure, exhibits interesting solubility characteristics that can be influenced by various factors. This compound is characterized by the presence of both hydrophobic phenyl and tolyl groups alongside the hydrophilic amine functional group, contributing to its solubility profile.

Factors Affecting Solubility

  • Polarity: The balance between polar and non-polar regions within the molecule influences its affinity for polar solvents such as water versus non-polar solvents like organic solvents.
  • Temperature: Variation in temperature can enhance or decrease solubility due to altered molecular interactions.
  • pH Level: The amine group may be protonated in acidic conditions, enhancing its solubility in water.

As a result, N,N-dimethyl-2-[phenyl(p-tolyl)methoxy]ethanamine is generally expected to have improved solubility in organic solvents like dichloromethane and ethanol, while its solubility in water may be limited. It is important to note that common solubility trends dictate that:

  • “Like dissolves like”: polar solvents dissolve polar compounds, and non-polar solvents dissolve non-polar compounds.
  • Hydrogen bonding: Compounds capable of extensive hydrogen bonding often exhibit higher solubility in polar solvents.

To summarize, the solubility of N,N-dimethyl-2-[phenyl(p-tolyl)methoxy]ethanamine is a unique interplay of its molecular structure and external conditions, warranting further investigation for practical applications.

Interesting facts

Interesting Facts about N,N-Dimethyl-2-[phenyl(p-tolyl)methoxy]ethanamine

N,N-Dimethyl-2-[phenyl(p-tolyl)methoxy]ethanamine, commonly referred to as a methoxy-substituted ethanamine, is a fascinating compound frequently studied in the field of organic chemistry due to its intriguing properties and potential applications. Here are some engaging insights:

  • Pharmaceutical Applications: This compound is part of a class of molecules that can exhibit interesting pharmacological activities. Research often explores its interaction with various receptors, contributing to potential therapeutic advancements.
  • Chemical Structure: The presence of both dimethyl groups and the methoxy substituent make this compound a candidate for studies on electron-donating effects, and may influence its reactivity and stability in various chemical environments.
  • Research Potential: A point of great interest is its modification potential. By altering substituents on the aromatic rings, scientists can investigate variations in biological activity, leading to the development of new medicinal compounds.
  • Pharmaceutical Innovation: Due to its structural characteristics, this compound can inspire the design of novel drugs aimed at treating various psychological and neurological disorders.

As noted by chemists, “The interplay of structure and function deepens our understanding of compound interactions in biological systems.” This underscores the importance of compounds like N,N-dimethyl-2-[phenyl(p-tolyl)methoxy]ethanamine in ongoing research endeavors. Its diverse applications highlight the richness of organic compounds in the quest for innovative solutions in medicine and beyond.

Synonyms
Toladryl
19804-27-4
4-Methyldiphenhydramine
p-Methyldiphenhydramine
Neo-benodine
UNII-P9633413CU
N,N-Dimethyl-2-[(4-methylphenyl)phenylmethoxy]ethanamine
EINECS 243-329-7
P9633413CU
ORPHENADRINE IMPURITY F
P-METHYL DIPHENHYDRAMINE
DIMENHYDRINATE IMPURITY G
p-Methylbenzhydryl 2-Dimethylaminoethyl Ether
Diphenhydramine Impurity B
P-METHYLDIPHENHYDRAMINE [MI]
P-METHYL DIPHENHYDRAMINE [WHO-DD]
4-METHYLDIPHEN HYDRAMINE [USP IMPURITY]
DIMENHYDRINATE IMPURITY G [EP IMPURITY]
ORPHENADRINE CITRATE IMPURITY F [EP IMPURITY]
DIPHENHYDRAMINE HYDROCHLORIDE IMPURITY B [EP IMPURITY]
P-METHYLBENZHYDRYL 2-DIMETHYLAMINOETHYL ETHER [WHO-DD]
Ethanamine, 2-[(4-methylphenyl)(phenyl)methoxy]-N,N-dimethyl-
ETHYLAMINE, N,N-DIMETHYL-2-((P-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-
N,N-DIMETHYL-N-(2-(P-METHYL-.ALPHA.-PHENYLBENZYLOXY)ETHYL)AMINE
4-METHYLDIPHEN HYDRAMINE (USP IMPURITY)
DIMENHYDRINATE IMPURITY G (EP IMPURITY)
ORPHENADRINE CITRATE IMPURITY F (EP IMPURITY)
N,N-Dimethyl-2-((4-methylphenyl)phenylmethoxy)ethanamine
DIPHENHYDRAMINE HYDROCHLORIDE IMPURITY B (EP IMPURITY)
Ethanamine, 2-((4-methylphenyl)(phenyl)methoxy)-N,N-dimethyl-
(+-)-4-METHYLDIPHENHYDRAMINE
ETHYLAMINE, N,N-DIMETHYL-2-((P-METHYL-ALPHA-PHENYLBENZYL)OXY)-
N,N-DIMETHYL-N-(2-(P-METHYL-ALPHA-PHENYLBENZYLOXY)ETHYL)AMINE
243-329-7
pjuyqwidniahiz-uhfffaoysa-n
Ethanamine, N,N-dimethyl-2-[(4-methylphenyl)phenylmethoxy]-
N,N-dimethyl-2-[(4-methylphenyl)-phenylmethoxy]ethanamine
N,N-Dimethyl-2-(phenyl(p-tolyl)methoxy)ethanamine
2-((p-Methyl-alpha-phenylbenzyl)oxy)ethyl(dimethyl)amine
Ethanamine, N,N-dimethyl-2-((4-methylphenyl)phenylmethoxy)-
SCHEMBL28837
DTXSID20903322
MFCD00484127
FT28302
(+/-)-4-METHYLDIPHENHYDRAMINE
AS-86143
HY-138110
CS-0145026
NS00047884
G70428
Q4637175
N,N-Dimethyl-2-[(4-methylphenyl)phenylmethoxy]ethanamine;4-Methyldiphenhydramine;p-Methyldiphenhydramine