Tramadol | Solubility of Things

Identification

Molecular formula

C₁₆H₂₅NO

CAS number

27203-92-5

IUPAC name

N,N-dimethyl-2,3,4,7,8,9-hexahydro-1H-benzo[7]annulen-9-amine

State

Tramadol is a solid at room temperature. In its pure form, it is often processed into tablet or capsule form for pharmaceutical use.

Melting point (Celsius)

180.00

Melting point (Kelvin)

453.15

Boiling point (Celsius)

372.70

Boiling point (Kelvin)

645.85

General information

Molecular weight

263.38g/mol

Molar mass

263.3810g/mol

Density

1.1330g/cm³

Appearence

Tramadol appears as a white or off-white crystalline powder. It is typically odorless and has a bitter taste. Commercially, it is often found in the form of its hydrochloride salt for improved solubility.

Comment on solubility

Solubility of N,N-dimethyl-2,3,4,7,8,9-hexahydro-1H-benzo[7]annulen-9-amine

N,N-dimethyl-2,3,4,7,8,9-hexahydro-1H-benzo[7]annulen-9-amine is an interesting compound in terms of solubility due to its complex molecular structure. Understanding its solubility can provide significant insights into its behavior in different environments. Here are some key points regarding its solubility:

Solvent Compatibility: The solubility of this compound typically depends on the nature of the solvent. Non-polar solvents might dissolve it better due to its hydrophobic regions, while polar solvents may struggle.
Temperature Influence: Increasing temperature can enhance solubility for many organic compounds, and this compound is likely to behave similarly, facilitating greater interaction with such solvents.
Concentration Effects: At higher concentrations, this compound may encounter solubility limits, leading to precipitation in certain solvents.
pH Sensitivity: If the benzo[7]annulen-9-amine is protonated, it may display significantly different solubility characteristics, particularly in aqueous environments.

In summary, the solubility of N,N-dimethyl-2,3,4,7,8,9-hexahydro-1H-benzo[7]annulen-9-amine is influenced by a variety of factors, including solvent type, temperature, concentration, and pH. Experimentation is often required to ascertain precise solubility limits in different systems. As quoted, “Understanding a compound’s solubility is crucial for anticipating its interactions and utility in chemical applications.”

Interesting facts

Interesting Facts about N,N-Dimethyl-2,3,4,7,8,9-hexahydro-1H-benzo[7]annulen-9-amine

N,N-Dimethyl-2,3,4,7,8,9-hexahydro-1H-benzo[7]annulen-9-amine, often referred to in research circles as simply "DMTB," is a fascinating compound that exemplifies the intersection of organic chemistry and medicinal applications. Here are some interesting aspects of this intriguing chemical:

Structural Unique: The compound features a complex polycyclic structure that showcases the versatility of amine functionalities within larger frameworks.
Synthetic Pathways: Its synthesis often involves multi-step organic reactions, making it a good example of advanced techniques in synthetic chemistry, including cyclization and amination.
Reactivity: The presence of multiple hydrogens in the cycloalkane rings lends unique properties to the reactivity of the compound, making it a subject of study for chemists interested in hydrogenation and aromaticity.
Potential Applications: Research has indicated that derivatives of this compound may exhibit biological activity, prompting investigation into applications in pharmaceuticals and materials science.
Research Significance: It serves as a model compound for understanding the behavior of larger heterocycles and their potential biological effects, particularly in drug design.

As noted by many in the field, "The study of complex organic molecules like DMTB opens the door to innovative solutions in both chemical synthesis and therapeutic design." The ongoing exploration of this compound reflects the dynamic nature of chemical research, where each structure has the potential to unveil new scientific horizons.