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LY-293284

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Identification
Molecular formula
C18H25N3
CAS number
142235-35-0
IUPAC name
N,N-dimethyl-3-(1-piperidylmethyl)-1H-indol-5-amine
State
State
At room temperature, LY-293284 exists as a solid, often handled and stored in its crystalline form in laboratory settings.
Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
425.00
Boiling point (Kelvin)
698.15
General information
Molecular weight
283.42g/mol
Molar mass
283.4160g/mol
Density
1.1660g/cm3
Appearence

LY-293284 appears as a solid compound, typically forming crystalline structures. It is often a pale to off-white color, depending on the degree of purity and the presence of any impurities.

Comment on solubility

Solubility of N,N-dimethyl-3-(1-piperidylmethyl)-1H-indol-5-amine

N,N-dimethyl-3-(1-piperidylmethyl)-1H-indol-5-amine is a compound with intriguing solubility characteristics. Understanding its solubility can provide valuable insights into its potential applications.

General Solubility Behavior

The solubility of this compound can be influenced by several factors:

  • Polarity: Being an amine, the presence of polar functional groups may enhance solubility in polar solvents, such as water.
  • Temperature: Increased temperature typically increases solubility for many organic compounds, making thermal conditions an important factor.
  • pH Levels: The pH of the environment can affect the ionization of the compound, thus impacting its solubility; for example, in more acidic conditions, the amine might become protonated, increasing solubility in aqueous solutions.

Solvent Interaction

This compound tends to have:

  • High solubility in organic solvents such as ethanol and methanol.
  • Limited solubility in nonpolar solvents due to the presence of polar piperidine and indole structures.

In summary, the solubility of N,N-dimethyl-3-(1-piperidylmethyl)-1H-indol-5-amine can significantly vary based on solvent choice and environmental factors. As always, conducting actual solubility tests under controlled conditions is the best method to obtain precise data.

Interesting facts

N,N-dimethyl-3-(1-piperidylmethyl)-1H-indol-5-amine: An Insight

N,N-dimethyl-3-(1-piperidylmethyl)-1H-indol-5-amine is an intriguing compound known for its significant implications in various fields of research, particularly in medicinal chemistry. This compound belongs to the indole class, which has been recognized for its diverse range of biological activities. Here are some interesting facts about this compound:

  • Structural Features: The structure incorporates both an indole moiety and a piperidine group, offering a unique blend of properties that can influence pharmacological activity.
  • Biological Relevance: Compounds containing indole derivatives have been studied extensively for their roles in neurotransmission and their potential as therapeutic agents in treating a variety of neurological disorders.
  • Research Applications: This compound may serve as a lead compound in the development of new drugs targeting serotonin receptors due to its intricate relationship with the neurotransmitter system.
  • Potential Activities: Preliminary studies suggest that similar compounds may exhibit analgesic, antidepressive, and anxiolytic effects, showcasing the versatility of indole derivatives in pharmacology.
  • Synthesis Considerations: The synthesis of this compound can be a challenge in synthetic organic chemistry, revealing insights into reaction mechanisms and the development of new synthetic pathways.

In conclusion, N,N-dimethyl-3-(1-piperidylmethyl)-1H-indol-5-amine is a compound with promising potential, standing at the intersection of chemistry and pharmacology. Its unique structure invites continued exploration and innovation in drug development.

Synonyms
BRN 0411332
INDOLE, 5-(DIMETHYLAMINO)-3-(PIPERIDINOMETHYL)-
1-(5'-Dimethylamino-3'-indolymethyl)piperidine
6851-68-9
DTXSID20218640
DTXCID70141131
5-22-11-00288 (beilstein handbook reference)