Skip to main content

Agomelatine

ADVERTISEMENT
Identification
Molecular formula
C17H19NO
CAS number
138112-76-2
IUPAC name
N,N-dimethyl-3-(1,2,3,4-tetrahydrocarbazol-9-yl)propan-1-amine
State
State

At room temperature, Agomelatine exists in a solid crystalline form.

Melting point (Celsius)
107.00
Melting point (Kelvin)
380.00
Boiling point (Celsius)
540.40
Boiling point (Kelvin)
813.60
General information
Molecular weight
243.36g/mol
Molar mass
243.3560g/mol
Density
1.1620g/cm3
Appearence

Agomelatine appears as a white to slightly yellow crystalline powder. It is typically odorless and is used in pharmaceutical formulations.

Comment on solubility

Solubility of N,N-Dimethyl-3-(1,2,3,4-tetrahydrocarbazol-9-yl)propan-1-amine

N,N-dimethyl-3-(1,2,3,4-tetrahydrocarbazol-9-yl)propan-1-amine, commonly referred to as a substituted amine, presents unique solubility characteristics that are crucial for its practical applications. Understanding its solubility is fundamental for various fields, particularly in pharmaceuticals and chemistry.

Solubility Characteristics:

  • Polar vs. Nonpolar: This compound exhibits a balance of polar and nonpolar characteristics due to its amine group and hydrophobic carbazole moiety, affecting its dissolution in solvents.
  • Solvent Compatibility: It is generally more soluble in organic solvents such as ethanol, methanol, and chloroform, while demonstrating limited solubility in water.
  • Influence of Temperature: As with many organic compounds, increasing the temperature typically enhances solubility, thereby facilitating its use in reactions at elevated temperatures.

To summarize, the solubility of N,N-dimethyl-3-(1,2,3,4-tetrahydrocarbazol-9-yl)propan-1-amine in appropriate solvents is crucial for its utility in various applications. As a rule of thumb, it is often more soluble in nonpolar solvents and shows lower compatibility with polar solvents like water. This suggests that careful consideration must be taken when preparing solutions for experimental work.

Interesting facts

Interesting Facts about N,N-dimethyl-3-(1,2,3,4-tetrahydrocarbazol-9-yl)propan-1-amine

N,N-dimethyl-3-(1,2,3,4-tetrahydrocarbazol-9-yl)propan-1-amine is a fascinating compound that attracts interest in various fields of study, particularly in medicinal chemistry and pharmacology. Here are some notable points about this intriguing chemical:

  • Structural Complexity: The compound features a complex structure that includes a tetrahydrocarbazole moiety, which contributes to its unique properties and potential biological activities.
  • Biological Relevance: Compounds derived from the carbazole family have been studied for their various pharmacological activities, including antioxidant, anti-inflammatory, and anticancer effects. This opens up avenues for medicinal applications.
  • Dimethylation Impact: The presence of dimethyl groups on the amine function alters the steric and electronic properties of the compound, potentially enhancing its binding affinity to biological targets.
  • Research Potential: Investigating this compound can reveal insights into the mechanisms of action of similar structures, facilitating the design of new drugs aimed at specific receptors or enzymes.

As with many compounds in the field of organic chemistry, understanding the reactivity and interactions of N,N-dimethyl-3-(1,2,3,4-tetrahydrocarbazol-9-yl)propan-1-amine can provide valuable knowledge not just for theoretical studies, but also practical applications in pharmaceutical development. In the words of a leading researcher, "The interplay of structure and function in such compounds is a key to unlocking their full potential."