Mibefradil | Solubility of Things

Identification

Molecular formula

C₂₉H₃₇N₅O₃

CAS number

116666-63-8

IUPAC name

N,N-dimethyl-3-[2-(2-morpholinoethyl)-5-nitro-benzimidazol-1-yl]propan-1-amine

State

Mibefradil is typically in a crystalline solid state at room temperature.

Melting point (Celsius)

177.00

Melting point (Kelvin)

450.15

Boiling point (Celsius)

540.00

Boiling point (Kelvin)

813.15

General information

Molecular weight

495.65g/mol

Molar mass

495.5840g/mol

Density

1.2375g/cm³

Appearence

Mibefradil is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of N,N-dimethyl-3-[2-(2-morpholinoethyl)-5-nitro-benzimidazol-1-yl]propan-1-amine

The solubility of N,N-dimethyl-3-[2-(2-morpholinoethyl)-5-nitro-benzimidazol-1-yl]propan-1-amine can be influenced by several factors, including its molecular structure and the polarity of its functional groups. This compound features a complex structure, which may dictate its solubility characteristics in various solvents.

Key Factors Affecting Solubility:

Polarity: The presence of polar functional groups such as amines and nitro groups often increases interactions with polar solvents, possibly enhancing solubility in water and alcohols.
Molecular Weight: Being a relatively large molecule, its overall size may hinder solubility in very nonpolar solvents.
Hydrogen Bonding: The ability of the compound to form hydrogen bonds can significantly affect solubility; stronger hydrogen bonding with solvent molecules typically results in greater solubility.

In general, this compound is likely to show higher solubility in polar solvents due to its functional groups. However, one must conduct solubility tests to determine the precise solubility profile. As a useful insight, it is often observed that “the rule of thumb is that like dissolves like,” meaning polar compounds tend to dissolve well in polar solvents, while nonpolar compounds do so in nonpolar solvents. Therefore, understand that the solubility of N,N-dimethyl-3-[2-(2-morpholinoethyl)-5-nitro-benzimidazol-1-yl]propan-1-amine will be critical for its practical applications in pharmaceuticals and chemistries.

Interesting facts

Interesting Facts about N,N-dimethyl-3-[2-(2-morpholinoethyl)-5-nitro-benzimidazol-1-yl]propan-1-amine

N,N-dimethyl-3-[2-(2-morpholinoethyl)-5-nitro-benzimidazol-1-yl]propan-1-amine is a fascinating compound with noteworthy characteristics and applications. Here are some intriguing aspects:

Pharmaceutical Relevance: This compound has garnered attention in the pharmaceutical industry, particularly for its potential use in developing therapeutic agents that target various biological systems.
Chemical Structure: The chemical structure features a complex arrangement that combines the properties of benzimidazole and morpholine, which are known for their biological activity.
Mechanism of Action: Compounds like this one often interact with specific biological pathways, and research suggests they may inhibit processes related to cell proliferation or act as antimicrobial agents.
Derivatives and Analogues: The study of derivatives and analogues based on this compound can lead to the discovery of substances with enhanced efficacy or reduced side effects, making it a promising candidate for drug development.
Research Opportunities: The structural elements of this compound provide numerous opportunities for scientists to explore modifications that could improve therapeutic outcomes or create novel mechanisms of action.

In conclusion, N,N-dimethyl-3-[2-(2-morpholinoethyl)-5-nitro-benzimidazol-1-yl]propan-1-amine illustrates the depth of complexity and potential within chemical compounds, highlighting the intersection of chemistry and medicine. As noted by researchers, "The design of innovative compounds is crucial in the ongoing battle against disease." This compound represents just a small yet significant piece of the larger puzzle in drug discovery.