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Cyclizine hydrochloride

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Identification
Molecular formula
C18H22ClN
CAS number
303-25-3
IUPAC name
N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride
State
State

At room temperature, cyclizine hydrochloride is in the form of a solid crystalline powder. It is stable under normal conditions when properly stored.

Melting point (Celsius)
198.50
Melting point (Kelvin)
471.65
Boiling point (Celsius)
254.00
Boiling point (Kelvin)
527.15
General information
Molecular weight
370.95g/mol
Molar mass
370.9510g/mol
Density
1.0190g/cm3
Appearence

Cyclizine hydrochloride appears as a white to off-white crystalline powder. It is hygroscopic in nature, meaning it has a tendency to absorb moisture from the air.

Comment on solubility

Solubility of N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine; hydrochloride

The solubility characteristics of N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine; hydrochloride can be analyzed through various angles, offering insights into its potential applications. It's essential to recognize that:

  • Hydrochloride Form: Being a hydrochloride salt typically enhances the solubility of organic compounds in water compared to their base forms. This solubilization can often result from ionization, which increases the compound's interaction with polar solvents like water.
  • Polarity: The presence of functional groups and the overall molecular structure contribute to the compound's polarity. Generally, compounds with higher polarity exhibit better solubility in polar solvents.
  • Temperature Dependency: Like many salts, the solubility could also depend on temperature. As the temperature increases, solubility typically increases in many cases, making it valuable for certain applications.

To summarize, the solubility of this hydrochloride salt is likely to be favorable in aqueous environments due to:

  1. Enhanced interactions with water.
  2. Potentially high polarity due to its functional groups.
  3. Increased solubility with temperature changes.

In conclusion, the solubility of N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine; hydrochloride presents a favorable profile for utilization in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about N,N-Dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine; Hydrochloride

N,N-Dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine; hydrochloride is a fascinating compound, primarily due to its unique molecular structure and potential applications. Below are some captivating insights:

Unique Structure

  • The compound features a complex tricyclic structure, which enhances its chemical properties and biological activity.
  • Its intricate arrangement allows for fascinating interactions within biological systems, making it a point of interest in pharmaceutical research.

Potential Therapeutic Applications

  • Due to its structural properties, this compound is being investigated for various therapeutic applications, including possible uses in treating neurological disorders.
  • The presence of the tricyclic moiety opens discussions regarding its interactions with neurotransmitter systems.

Chemistry and Research Opportunities

This compound serves as a fertile ground for research, particularly in medicinal chemistry and synthetic organic chemistry. Researchers are exploring:

  • The potential synthesis of similar compounds to increase biological efficacy.
  • Investigating structure-activity relationships that could lead to novel drug discovery.

In summary, N,N-Dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine; hydrochloride is much more than just a chemical formula. Its intricate structure and potential applications render it a captivating subject for ongoing research and exploration in the field of chemistry. As scientists continue to unveil its mysteries, who knows what exciting discoveries lie ahead?

Synonyms
Cyclobenzaprine hydrochloride
6202-23-9
Cyclobenzaprine HCL
Flexeril
Flexiban
3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
Cycloflex
Tensodox
Cloben
Cyben
Novo-Cycloprine
MK 130 hydrochloride
Proheptatriene hydrochloride
Tabradol
Yurelax
Miosan
Multi-Relax
Proheptatriene monohydrochloride
Proheptatrien monohydrochloride
Tonmya
UNII-0VE05JYS2P
EINECS 228-264-4
0VE05JYS2P
NSC 78206
NSC-78206
NSC 169900
NSC 173379
NSC-169900
NSC-173379
10,11delta-Amitriptyline hydrochloride
CHEBI:3997
DTXSID2045105
1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride
TNX-102 SL
DTXCID0025105
5-(3-Dimethylaminopropylidene)-5H-dibenzo-(a,d)cycloheptene hydrochloride
NSC169900
NSC173379
N,N-Dimethyl-5H-dibenzo(a,d)cycloheptene-delta(sup 5,gamma)-propylamine hydrochloride
Cyclobenzaprine hydrochloride [USAN:USP]
NSC78206
5H-Dibenzo(a,d)cycloheptene-delta(sup 5)-gamma-propylamine, N,N-dimethyl-, hydrochloride
5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, N,N-dimethyl-, hydrochloride
N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Delta(5,gamma)-propylamine hydrochloride
Cyclobenzaprine hydrochloride (USAN:USP)
CYCLOBENZAPRINE HYDROCHLORIDE (MART.)
CYCLOBENZAPRINE HYDROCHLORIDE [MART.]
CYCLOBENZAPRINE HYDROCHLORIDE (USP-RS)
CYCLOBENZAPRINE HYDROCHLORIDE [USP-RS]
CYCLOBENZAPRINE HYDROCHLORIDE (USP IMPURITY)
CYCLOBENZAPRINE HYDROCHLORIDE (USP MONOGRAPH)
CYCLOBENZAPRINE HYDROCHLORIDE [USP IMPURITY]
CYCLOBENZAPRINE HYDROCHLORIDE [USP MONOGRAPH]
3-(5H-dibenzo(a,d)(7)annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
CYCLOPHENE
Cyclobenzaprine HCLER
Cyclobenzaprine HCL ER
CYCLOBENZAPRINE HCI
Cyclobenzaprine Hyrochloride
FR2100873
N,N-DIMETHYL-5H-DIBENZO(A,D)CYCLOHEPTENE-(SUP delta5,gamma)-PROPYLAMINE HYDROCHLORIDE
228-264-4
Amrix
Cyclobenzaprine (hydrochloride)
MK130 hydrochloride
TNX-102
5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene hydrochloride
Cyclobenzaprine.HCl
N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride
Flexeril hydrochloride
MK-130 HCl
10,11.delta.-Amitriptyline hydrochloride
3-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine Hydrochloride (Cyclobenzaprine Hydrochloride)
WLN: L C676 BHJ B3N1&1 &GH
5H-Dibenzo[a, N,N-dimethyl-, hydrochloride
SR-01000075761
Cyclobenzaprine hydrochloride [USAN]
CAS-6202-23-9
5H-Dibenzo[a,.gamma.-propylamine, N,N-dimethyl-, hydrochloride
N,d]cycloheptene-.delta.,5.gamma.-propylamine, hydrochloride
1-Propanamine,d]cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride
N,d]cycloheptene-.delta.(sup5,.gamma.)-propylamine hydrochloride
5-[3-(Dimethylamino)propylidene]-5H-dibenzo-[a,d]cycloheptene hydrochloride
Flexeril (TN)
Prestwick_790
MFCD00079039
Cyclobenzaprine HCl?
SCHEMBL41376
MLS002153815
MK-130 HYDROCHLORIDE
SPECTRUM1503207
CHEMBL1200636
HY-B0740R
TNX-105
HMS1569I12
HMS1922I11
Pharmakon1600-01503207
BCP21781
Cyclobenzaprine hydrochloride (USP)
EUR-1002
HY-B0740
Tox21_110040
Tox21_500303
CCG-39312
NSC758414
s4283
3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)propyl(dimethyl)ammonium chloride
AKOS015906329
Tox21_110040_1
AC-1916
BCP9000565
FC64990
LP00303
NSC-758414
SB19022
NCGC00013841-01
NCGC00013841-09
NCGC00093752-01
NCGC00093752-02
NCGC00093752-03
NCGC00093752-04
NCGC00093752-05
NCGC00095017-01
NCGC00095017-02
NCGC00095017-03
NCGC00095017-04
NCGC00260988-01
AS-15745
BC181325
CYCLOBENZAPRINE HYDROCHLORIDE [MI]
SMR000326702
Cyclobenzaprine (hydrochloride) (Standard)
C3157
CYCLOBENZAPRINE HYDROCHLORIDE [VANDF]
EU-0100303
SW196928-3
CYCLOBENZAPRINE HYDROCHLORIDE [WHO-DD]
C 4542
D00772
L10029
CYCLOBENZAPRINE HYDROCHLORIDE [ORANGE BOOK]
SR-01000075761-1
SR-01000075761-6
Q27106282
Cyclobenzaprine.HCl, 1mg/ml in Methanol (as free base)
Z1575278780
Cyclobenzaprine Hydrochloride 1.0 mg/ml in Methanol (as free base)
3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-aminehydrochloride
Cyclobenzaprine hydrochloride, European Pharmacopoeia (EP) Reference Standard
N,N-DIMETHYL-5H-DIBENZO(A,D)CYCLOHEPTENE-(SUP .DELTA.5,.GAMMA.)-PROPYLAMINE HYDROCHLORIDE