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(tofisopam)

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Identification
Molecular formula
C21H25F3N2O
CAS number
3575-80-2
IUPAC name
N,N-dimethyl-3-[[3-(trifluoromethyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl]oxy]propan-1-amine
State
State

This compound is typically a solid at room temperature.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
525.20
Boiling point (Kelvin)
798.30
General information
Molecular weight
352.44g/mol
Molar mass
352.4160g/mol
Density
1.2478g/cm3
Appearence

A pale yellow solid with an appearance that may vary slightly depending on the degree of purity and particle size. It typically appears as a crystalline powder.

Comment on solubility

Solubility of N,N-Dimethyl-3-[[3-(Trifluoromethyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl]oxy]propan-1-amine

The solubility characteristics of N,N-dimethyl-3-[[3-(trifluoromethyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl]oxy]propan-1-amine can present significant interest due to its complex structure. Here are several key points regarding its solubility:

  • Polarity: The presence of both the N,N-dimethyl and trifluoromethyl groups suggests a mixed polarity nature, affecting how this compound interacts with solvents.
  • Solvent Compatibility: It is likely to exhibit reasonable solubility in polar organic solvents such as dimethyl sulfoxide (DMSO) or methanol, while solubility in non-polar solvents may be limited.
  • Hydrogen Bonding: The potential for hydrogen bonding, particularly due to the amino group, can enhance its solubility in polar solvents, promoting interactions with water.
  • Environmental Factors: Factors like temperature can significantly influence solubility, often increasing as temperature rises.

In general, compounds with complex molecular structures often exhibit variable solubility, which may be attributed to various factors such as molecular size, the presence of functional groups, and solvent properties. As with many chemical entities, experimental determination is crucial to ascertain precise solubility values and behaviour in different environments.

Interesting facts

Exploring N,N-Dimethyl-3-[[3-(trifluoromethyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl]oxy]propan-1-amine

This intriguing compound, N,N-dimethyl-3-[[3-(trifluoromethyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl]oxy]propan-1-amine, showcases a fascinating structural complexity that offers rich potential in the field of medicinal chemistry. Here are some notable facts about this compound:

  • Pharmacological Applications: Compounds of this nature are often studied for their potential therapeutic effects, particularly in areas such as neuropharmacology and psychiatry. The unique structural features can impart significant biological activity.
  • Role of Fluorine: The presence of the trifluoromethyl group is particularly noteworthy. Fluorinated compounds can enhance the metabolic stability and lipophilicity, making this compound potentially more effective in drug development.
  • Structural Innovation: The cyclohepta-quinoline core is a captivating motif that can exhibit various reactivity patterns, useful in synthesizing novel derivatives that may have enhanced properties.
  • Complex Interactions: Due to its intricate design, this compound can engage in a range of intermolecular interactions, which can influence its activity in biological systems.
  • Continuing Research: Ongoing studies are critical for understanding the full scope of the biological activities associated with this compound, potentially leading to breakthroughs in therapeutic applications.

As a compound with such intricate structural features, N,N-dimethyl-3-[[3-(trifluoromethyl)-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl]oxy]propan-1-amine is a prime example of how chemistry can bridge the gap between structure and function, paving the way for advancements in medicinal chemistry and drug design.