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Amitriptyline

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Identification
Molecular formula
C19H23NO
CAS number
50-48-6
IUPAC name
N,N-dimethyl-3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine
State
State

Amitriptyline is typically solid at room temperature. It is also available in tablet or capsule form for oral administration.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
277.40g/mol
Molar mass
277.4030g/mol
Density
1.2770g/cm3
Appearence

Amitriptyline is usually found as a white or slightly yellow crystalline powder. It might also come in tablet form for pharmaceutical use. The compound is relatively stable when stored properly.

Comment on solubility

Solubility Characteristics of N,N-dimethyl-3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine

N,N-dimethyl-3-(5-oxo-6H-benzo[1]benzothiepin-11-ylidene)propan-1-amine, a complex organic compound, exhibits unique solubility properties that warrant careful consideration. Understanding its solubility is crucial for applications in pharmaceuticals and organic synthesis.

Key Points on Solubility:

  • Solvent Interaction: Generally, the solubility of this compound is influenced by polarity. It tends to dissolve better in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), or methanol than in water due to its hydrophobic regions.
  • pH Dependence: The solubility may also vary significantly with changes in pH, particularly when the amine group is protonated. This can enhance its solubility in more acidic solutions.
  • Temperature Effects: Like many organic compounds, an increase in temperature generally leads to greater solubility, enabling easier dissolution and processing in various applications.
  • Chemical Structure Influence: The unique structure of the compound, with its benzo[c]benzothiepin framework, contributes to its solubility characteristics. The presence of multiple functional groups can lead to various solvate interactions.

In summary, while N,N-dimethyl-3-(5-oxo-6H-benzo[1]benzothiepin-11-ylidene)propan-1-amine shows limited solubility in water, its compatibility with organic solvents and dependency on environmental factors plays a significant role in its usability. Understanding these aspects can lead to optimized formulations and enhanced utility in scientific applications.

Interesting facts

Interesting Facts about N,N-Dimethyl-3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine

This intriguing compound, often referred to in scientific circles, showcases the complex interplay of various functional groups and structures that define modern organic chemistry.

Key Highlights

  • Diverse Framework: The structure integrates both a dimethyl amine section and a benzothiepin moiety, which contributes to interesting reactivity and interaction patterns typical in pharmaceuticals.
  • Pharmacological Potential: Compounds containing benzothiepin structures are known for their unique therapeutic activities. Research suggests potential applications in treating neurological and psychiatric disorders.
  • Versatile Synthesis: The synthesis of such compounds often involves multi-step processes. This highlights the creativity and innovation that chemists utilize in the laboratory to construct complex molecules.
  • Mechanistic Insights: Understanding the mechanism of action for compounds like this requires a deep dive into molecular interactions, receptor binding, and the resultant biological pathways.

As scientists and students explore the depths of organic chemistry, compounds such as N,N-dimethyl-3-(5-oxo-6H-benzo[c][1]benzothiepin-11-ylidene)propan-1-amine serve as reminders of the vast potential for drug discovery and the underlying principles of chemical interactions. Each structural nuance can influence its properties and applications, making it an exciting area of study.

In the words of a notable chemist, "The beauty of chemistry lies in its complexity and the stories that every compound tells." This compound, rich in structure and application potential, is a perfect example of that complexity.

Synonyms
DTXSID901315633
NS00044851