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N,N-dimethyl-3-(morpholinomethyl)indol-5-amine

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Identification
Molecular formula
C15H21N3O
CAS number
63733-73-1
IUPAC name
N,N-dimethyl-3-(morpholinomethyl)-1H-indol-5-amine
State
State

At room temperature, N,N-dimethyl-3-(morpholinomethyl)indol-5-amine is typically found in a solid state. It is stable under normal conditions but should be stored in a cool, dry place to maintain its stability and prevent decomposition.

Melting point (Celsius)
129.00
Melting point (Kelvin)
402.15
Boiling point (Celsius)
490.00
Boiling point (Kelvin)
763.15
General information
Molecular weight
287.36g/mol
Molar mass
287.3730g/mol
Density
1.2336g/cm3
Appearence

N,N-dimethyl-3-(morpholinomethyl)indol-5-amine typically appears as a solid compound with a crystalline structure. Its color can range from off-white to light beige. The compound's hygroscopic nature means it can absorb moisture from the air.

Comment on solubility

Solubility of N,N-dimethyl-3-(morpholinomethyl)-1H-indol-5-amine

N,N-dimethyl-3-(morpholinomethyl)-1H-indol-5-amine is a fascinating compound known for its diverse applications in medicinal chemistry. When discussing its solubility, several key points emerge:

  • Polar Nature: The presence of functional groups such as a morpholine ring contributes to the compound's polarity, which can enhance its solubility in polar solvents like water and alcohol.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to its nitrogen and oxygen atoms allows for better interaction with solvent molecules, potentially increasing solubility.
  • Solvent Compatibility: This compound shows good solubility in dimethyl sulfoxide (DMSO) and other organic solvents, making it suitable for various chemical reactions and formulations.

However, it is important to note that the actual solubility may vary significantly based on factors such as:

  • Temperature: Increased temperatures often enhance solubility, which is vital for applications that involve higher reaction temperatures.
  • pH Levels: The ionization state of the compound may change with pH, influencing its overall solubility in different environments.

In laboratory settings, a common quote is: "The solubility of a compound is a reflection of its molecular interactions." Understanding these interactions is critical when using N,N-dimethyl-3-(morpholinomethyl)-1H-indol-5-amine in research or industrial applications. Therefore, assessing the specific solubility characteristics is essential for effective utilization in various chemical contexts.

Interesting facts

Interesting Facts About N,N-dimethyl-3-(morpholinomethyl)-1H-indol-5-amine

N,N-dimethyl-3-(morpholinomethyl)-1H-indol-5-amine is a fascinating compound within the realm of medicinal chemistry. It has garnered attention for its potential applications in pharmacology due to its unique structural characteristics.

Key Features

  • Indole Framework: The compound incorporates an indole structure, which is integral to many biological systems, including neurotransmitter activity.
  • Morpholine Ring: The presence of a morpholinomethyl group enhances the compound's interaction with biological targets, making it significant for drug design.
  • Dimethyl Amine Group: The N,N-dimethyl modification can influence the lipophilicity and bioavailability, which are critical for therapeutic efficacy.

Potential Applications

This compound may play a role in:

  • Antidepressant Development: Its unique modifications suggest potential use in treating mood disorders.
  • Anticancer Research: Indole derivatives are known for their biological activity against various cancer cell lines, making this compound a point of interest.
  • Neuropharmacology: Given its structure, it may interact with neurotransmitter systems, which could be beneficial in neurological studies.

Scientific Insights

Chemistry students and scientists alike find this compound intriguing due to its complex interactions. As noted by a prominent researcher, “The intricate balance of structure and function in such compounds reveals the beauty of organic chemistry and the untapped potential in drug development.”

In summary, N,N-dimethyl-3-(morpholinomethyl)-1H-indol-5-amine stands out for its potential in emerging pharmaceutical applications, offering a rich field for research and discovery.

Synonyms
BRN 0998085
INDOLE, 5-(DIMETHYLAMINO)-3-MORPHOLINOMETHYL-
5-Dimethylamino-3-morpholinomethyl indole
7010-82-4
DTXSID20220384
DTXCID20142875