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N,N-Dimethylacetoacetamide

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Identification
Molecular formula
C6H11NO2
CAS number
2044-64-6
IUPAC name
N,N-dimethyl-3-oxo-butanamide
State
State
N,N-Dimethylacetoacetamide is typically found in the liquid state at room temperature.
Melting point (Celsius)
7.00
Melting point (Kelvin)
280.15
Boiling point (Celsius)
197.00
Boiling point (Kelvin)
470.15
General information
Molecular weight
115.14g/mol
Molar mass
115.1440g/mol
Density
0.9767g/cm3
Appearence

N,N-Dimethylacetoacetamide is a colorless to pale yellow liquid. It is usually clear and has a faint characteristic odor.

Comment on solubility

Solubility of N,N-dimethyl-3-oxo-butanamide

N,N-dimethyl-3-oxo-butanamide, with the chemical formula C5H9NO2, exhibits interesting solubility characteristics that can be attributed to its molecular structure.

Generally, this compound is:

  • Moderately soluble in polar solvents like water due to the presence of the amide group, which can engage in hydrogen bonding.
  • Soluble in organic solvents such as ethanol and methanol, enhancing its versatility in different chemical environments.
  • Less soluble in non-polar solvents, highlighting its polar nature.

It’s important to note that solubility can be influenced by factors such as temperature and pH. For example:

  • An increase in temperature often leads to improved solubility for many organic compounds.
  • Changing the pH can alter the ionic state of the compound, affecting its solubility in aqueous solutions.

In conclusion, the solubility of N,N-dimethyl-3-oxo-butanamide underscores the importance of molecular interactions in determining how well compounds dissolve in various solvents. Understanding these properties is crucial for applications in chemical synthesis and formulation.

Interesting facts

Interesting Facts about N,N-dimethyl-3-oxo-butanamide

N,N-dimethyl-3-oxo-butanamide is an intriguing compound that lies at the intersection of organic chemistry and medicinal applications. As a member of the amide functional group, this compound exhibits unique characteristics that make it a subject of study in various fields.

Key Features

  • Reactivity: The presence of the carbonyl group (C=O) in the molecule provides notable reactivity, allowing it to participate in various chemical reactions such as nucleophilic additions.
  • Applications: This compound has potential applications in the realm of pharmaceuticals, where it may be utilized as a building block for synthesizing larger, more complex molecules.
  • Biological Relevance: Given its structure, it could be investigated for its biological activity, with the hope of finding novel therapeutic agents.

In the Lab

When working with N,N-dimethyl-3-oxo-butanamide in a laboratory setting, chemists often focus on:

  • Synthesis Techniques: Exploring various synthetic routes that can lead to this compound, often requiring specific conditions and catalysts.
  • Characterization Methods: Employing techniques such as NMR spectroscopy and mass spectrometry to confirm the structure and purity of the compound.

Quote from the Field

As one researcher put it: "Understanding the chemistry of amides like N,N-dimethyl-3-oxo-butanamide opens doors to innovative drug design and development."

In summary, N,N-dimethyl-3-oxo-butanamide serves as an important compound in organic synthesis, presenting both challenges and opportunities for scientists devoted to advancing chemical knowledge and drug discovery. Its unique structural attributes make it a persistent point of interest in ongoing research efforts.

Synonyms
N,N-Dimethylacetoacetamide
N,N-Dimethyl-3-oxobutanamide
Butanamide, N,N-dimethyl-3-oxo-
N,N-Dimethyl-3-oxobutyramide
ACETOACETAMIDE, N,N-DIMETHYL-
Acetylacetamide, N,N-dimethyl-
dimethylacetoacetamide
Dimethylamid kyseliny acetoctove
UNII-7E2L0OAA4K
EINECS 218-059-8
7E2L0OAA4K
NSC 524755
BRN 1755038
Dimethylamid kyseliny acetoctove [Czech]
DTXSID8027454
NSC-524755
DTXCID607454
YPEWWOUWRRQBAX-UHFFFAOYSA-
EC 218-059-8
4-04-00-00260 (Beilstein Handbook Reference)
N,N-DIMETHYL-2-ACETOACETAMIDE
DMAAm cpd
inchi=1/c6h11no2/c1-5(8)4-6(9)7(2)3/h4h2,1-3h3
ypewwouwrrqbax-uhfffaoysa-n
2044-64-6
N-Acetoacetyldimethylamine
MFCD00038243
CAS-2044-64-6
dimethyl acetoacetamide
NN-Dimethylacetoacetamide
N,N-DIMETHYL ACETOACETAMIDE
N.N-Dimethylacetoacetamide
Acetoacetamide,N-dimethyl-
Acetylacetamide,N-dimethyl-
SCHEMBL56374
acetoacetic acid dimethylamide
Butanamide,N-dimethyl-3-oxo-
N,N-dimethyl-3-oxo-butyramide
CHEMBL3185062
N,N-Dimethyl-3-oxobutanamide #
Tox21_201898
Tox21_303265
NSC524755
STL183263
AKOS000120991
NCGC00249133-01
NCGC00257209-01
NCGC00259447-01
SY008180
DB-080755
CS-0155066
D0642
NS00009956
EN300-17523
E75883
Q27268134
Z56948269
F0001-0723